登録情報 | データベース: PDB / ID: 6uck |
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タイトル | proIAPP in DPC Micelles - Two-Conformer Ensemble Refinement, Bent Conformer |
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要素 | Islet amyloid polypeptide |
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キーワード | HORMONE / membrane-binding / IDP / amyloid |
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機能・相同性 | 機能・相同性情報
: / amylin receptor signaling pathway / Calcitonin-like ligand receptors / negative regulation of amyloid fibril formation / negative regulation of bone resorption / eating behavior / negative regulation of osteoclast differentiation / positive regulation of protein kinase A signaling / Regulation of gene expression in beta cells / negative regulation of protein-containing complex assembly ...: / amylin receptor signaling pathway / Calcitonin-like ligand receptors / negative regulation of amyloid fibril formation / negative regulation of bone resorption / eating behavior / negative regulation of osteoclast differentiation / positive regulation of protein kinase A signaling / Regulation of gene expression in beta cells / negative regulation of protein-containing complex assembly / positive regulation of calcium-mediated signaling / bone resorption / sensory perception of pain / osteoclast differentiation / hormone activity / cell-cell signaling / amyloid-beta binding / G alpha (s) signalling events / positive regulation of MAPK cascade / receptor ligand activity / positive regulation of apoptotic process / Amyloid fiber formation / signaling receptor binding / lipid binding / apoptotic process / signal transduction / extracellular space / extracellular region / identical protein binding類似検索 - 分子機能 Islet amyloid polypeptide / Calcitonin-like / Calcitonin peptide-like / Calcitonin, conserved site / Calcitonin / CGRP / IAPP family signature. / calcitonin / Calcitonin/adrenomedullin / Calcitonin / CGRP / IAPP family類似検索 - ドメイン・相同性 |
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生物種 | Homo sapiens (ヒト) |
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手法 | 溶液NMR / simulated annealing |
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データ登録者 | DeLisle, C.F. / Malooley, A.L. / Banerjee, I. / Lorieau, J.L. |
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資金援助 | 米国, 1件 組織 | 認可番号 | 国 |
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National Science Foundation (NSF, United States) | MCB1651598 | 米国 |
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引用 | ジャーナル: Febs J. / 年: 2020 タイトル: Pro-islet amyloid polypeptide in micelles contains a helical prohormone segment. 著者: DeLisle, C.F. / Malooley, A.L. / Banerjee, I. / Lorieau, J.L. |
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履歴 | 登録 | 2019年9月16日 | 登録サイト: RCSB / 処理サイト: RCSB |
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改定 1.0 | 2020年2月26日 | Provider: repository / タイプ: Initial release |
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改定 1.1 | 2020年3月4日 | Group: Database references / カテゴリ: citation / citation_author Item: _citation.pdbx_database_id_PubMed / _citation.title / _citation_author.identifier_ORCID |
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改定 1.2 | 2020年10月28日 | Group: Database references / カテゴリ: citation / citation_author Item: _citation.journal_volume / _citation.page_first ..._citation.journal_volume / _citation.page_first / _citation.page_last / _citation.title / _citation_author.identifier_ORCID |
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改定 1.3 | 2023年6月14日 | Group: Database references / Other / カテゴリ: database_2 / pdbx_database_status Item: _database_2.pdbx_DOI / _database_2.pdbx_database_accession / _pdbx_database_status.status_code_nmr_data |
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