登録情報 データベース : PDB / ID : 6tjt 構造の表示 ダウンロードとリンクタイトル Neuropilin2-b1 domain in a complex with the C-terminal VEGFC peptide 要素Neuropilin-2 VEGFC C terminal peptide 詳細キーワード SIGNALING PROTEIN / VEGF-binding / NRP2 / angiogenesis / immunomodulation機能・相同性 機能・相同性情報分子機能 ドメイン・相同性 構成要素
vascular endothelial growth factor receptor 3 binding / substrate-dependent cell migration / regulation of vascular endothelial growth factor receptor signaling pathway / vestibulocochlear nerve structural organization / dorsal root ganglion morphogenesis / ventral trunk neural crest cell migration / sympathetic neuron projection guidance / facioacoustic ganglion development / trigeminal ganglion development / positive regulation of lymphangiogenesis ... vascular endothelial growth factor receptor 3 binding / substrate-dependent cell migration / regulation of vascular endothelial growth factor receptor signaling pathway / vestibulocochlear nerve structural organization / dorsal root ganglion morphogenesis / ventral trunk neural crest cell migration / sympathetic neuron projection guidance / facioacoustic ganglion development / trigeminal ganglion development / positive regulation of lymphangiogenesis / trigeminal nerve structural organization / sensory neuron axon guidance / facial nerve structural organization / gonadotrophin-releasing hormone neuronal migration to the hypothalamus / branchiomotor neuron axon guidance / VEGF ligand-receptor interactions / positive regulation of mast cell chemotaxis / axon extension involved in axon guidance / positive regulation of mesenchymal stem cell proliferation / morphogenesis of embryonic epithelium / sympathetic neuron projection extension / NrCAM interactions / Neurophilin interactions with VEGF and VEGFR / VEGF binds to VEGFR leading to receptor dimerization / sympathetic ganglion development / neural crest cell migration involved in autonomic nervous system development / vascular endothelial growth factor receptor activity / nerve development / induction of positive chemotaxis / outflow tract septum morphogenesis / semaphorin receptor activity / semaphorin receptor complex / sprouting angiogenesis / vascular endothelial growth factor signaling pathway / regulation of postsynapse organization / negative chemotaxis / positive regulation of neuroblast proliferation / cytokine binding / chemoattractant activity / growth factor binding / semaphorin-plexin signaling pathway / positive regulation of cell division / positive regulation of blood vessel endothelial cell migration / negative regulation of osteoblast differentiation / glial cell proliferation / vascular endothelial growth factor receptor signaling pathway / positive regulation of glial cell proliferation / positive regulation of protein autophosphorylation / positive regulation of endothelial cell proliferation / negative regulation of blood pressure / positive regulation of endothelial cell migration / platelet alpha granule lumen / cellular response to leukemia inhibitory factor / positive regulation of protein secretion / animal organ morphogenesis / axon guidance / growth factor activity / positive regulation of angiogenesis / Platelet degranulation / signaling receptor activity / heparin binding / postsynaptic membrane / angiogenesis / response to hypoxia / cell adhesion / response to xenobiotic stimulus / positive regulation of protein phosphorylation / axon / glutamatergic synapse / positive regulation of cell population proliferation / signal transduction / extracellular space / extracellular region / identical protein binding / membrane / metal ion binding / plasma membrane 類似検索 - 分子機能 CXCXC repeat / CXCXC repeat / Neuropilin / Neuropilin, C-terminal / C-terminal domain of neuropilin glycoprotein / PDGF/VEGF domain / Platelet-derived growth factor, conserved site / PDGF/VEGF domain / Platelet-derived growth factor (PDGF) family signature. / Platelet-derived growth factor (PDGF) family profile. ... CXCXC repeat / CXCXC repeat / Neuropilin / Neuropilin, C-terminal / C-terminal domain of neuropilin glycoprotein / PDGF/VEGF domain / Platelet-derived growth factor, conserved site / PDGF/VEGF domain / Platelet-derived growth factor (PDGF) family signature. / Platelet-derived growth factor (PDGF) family profile. / Platelet-derived and vascular endothelial growth factors (PDGF, VEGF) family / Domain in meprin, A5, receptor protein tyrosine phosphatase mu (and others) / MAM domain, meprin/A5/mu / MAM domain / MAM domain profile. / Coagulation factors 5/8 type C domain (FA58C) signature 2. / Coagulation factors 5/8 type C domain (FA58C) signature 1. / CUB domain / Domain first found in C1r, C1s, uEGF, and bone morphogenetic protein. / CUB domain / CUB domain profile. / Spermadhesin, CUB domain superfamily / Coagulation factor 5/8 C-terminal domain, discoidin domain / Coagulation factors 5/8 type C domain (FA58C) profile. / Cystine-knot cytokine / F5/8 type C domain / Coagulation factor 5/8 C-terminal domain / Galactose-binding-like domain superfamily / Concanavalin A-like lectin/glucanase domain superfamily 類似検索 - ドメイン・相同性 Neuropilin-2 / Vascular endothelial growth factor C 類似検索 - 構成要素生物種 Homo sapiens (ヒト)手法 X線回折 / シンクロトロン / 分子置換 / 解像度 : 1.31 Å 詳細データ登録者 Eldrid, C. / Yu, L. / Yelland, T. / Fotinou, C. / Djordjevic, S. 引用ジャーナル : To Be Published タイトル : NRP2-b1 domain in a complex with the C-terminal VEGFC peptide著者 : Eldrid, C. / Yu, L. / Yelland, T. / Fotinou, C. / Djordjevic, S. 履歴 登録 2019年11月26日 登録サイト : PDBE / 処理サイト : PDBE改定 1.0 2020年12月16日 Provider : repository / タイプ : Initial release改定 1.1 2024年1月24日 Group : Data collection / Database references / Refinement descriptionカテゴリ : chem_comp_atom / chem_comp_bond ... chem_comp_atom / chem_comp_bond / database_2 / pdbx_initial_refinement_model Item : _database_2.pdbx_DOI / _database_2.pdbx_database_accession
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