登録情報 | データベース: PDB / ID: 6tiu |
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タイトル | DROSOPHILA GTP-TUBULIN Y222F MUTANT |
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要素 | - Stathmin-4
- Tubulin alpha-1 chain
- Tubulin beta-1 chain
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キーワード | CELL CYCLE / MICROTUBULE / MICROTUBULE DYNAMICS / MICROTULE NUCLEATION |
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機能・相同性 | 機能・相同性情報
HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand / COPI-mediated anterograde transport / COPI-independent Golgi-to-ER retrograde traffic / COPI-dependent Golgi-to-ER retrograde traffic / Kinesins / astral microtubule / Neutrophil degranulation / lysosome localization / microtubule depolymerization / regulation of microtubule polymerization or depolymerization ...HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand / COPI-mediated anterograde transport / COPI-independent Golgi-to-ER retrograde traffic / COPI-dependent Golgi-to-ER retrograde traffic / Kinesins / astral microtubule / Neutrophil degranulation / lysosome localization / microtubule depolymerization / regulation of microtubule polymerization or depolymerization / tubulin binding / 加水分解酵素; 酸無水物に作用; GTPに作用・細胞または細胞小器官の運動に関与 / structural constituent of cytoskeleton / microtubule cytoskeleton organization / spindle / neuron projection development / mitotic cell cycle / growth cone / microtubule / hydrolase activity / neuron projection / GTPase activity / centrosome / GTP binding / perinuclear region of cytoplasm / Golgi apparatus / nucleus / metal ion binding / cytoplasm類似検索 - 分子機能 Stathmin family / Stathmin, conserved site / Stathmin superfamily / Stathmin family / Stathmin family signature 1. / Stathmin family signature 2. / Stathmin-like (SLD) domain profile. / Alpha tubulin / Tubulin-beta mRNA autoregulation signal. / Beta tubulin, autoregulation binding site ...Stathmin family / Stathmin, conserved site / Stathmin superfamily / Stathmin family / Stathmin family signature 1. / Stathmin family signature 2. / Stathmin-like (SLD) domain profile. / Alpha tubulin / Tubulin-beta mRNA autoregulation signal. / Beta tubulin, autoregulation binding site / Beta tubulin / Tubulin / Tubulin, C-terminal / Tubulin C-terminal domain / Tubulin, conserved site / Tubulin subunits alpha, beta, and gamma signature. / Tubulin/FtsZ family, C-terminal domain / Tubulin/FtsZ-like, C-terminal domain / Tubulin/FtsZ, C-terminal / Tubulin/FtsZ, 2-layer sandwich domain / Tubulin/FtsZ family, GTPase domain / Tubulin/FtsZ family, GTPase domain / Tubulin/FtsZ, GTPase domain / Tubulin/FtsZ, GTPase domain superfamily類似検索 - ドメイン・相同性 GUANOSINE-5'-DIPHOSPHATE / GUANOSINE-5'-TRIPHOSPHATE / Tubulin alpha-1 chain / Stathmin-4 / Tubulin beta-1 chain類似検索 - 構成要素 |
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生物種 | ![](img/tx_arthropod.gif) Drosophila melanogaster (キイロショウジョウバエ)
![](img/tx_mammal.gif) Rattus norvegicus (ドブネズミ) |
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手法 | X線回折 / シンクロトロン / フーリエ合成 / 解像度: 3.571 Å |
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データ登録者 | Gigant, B. |
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引用 | ジャーナル: J.Cell Biol. / 年: 2021 タイトル: GTP-dependent formation of straight tubulin oligomers leads to microtubule nucleation. 著者: Ayukawa, R. / Iwata, S. / Imai, H. / Kamimura, S. / Hayashi, M. / Ngo, K.X. / Minoura, I. / Uchimura, S. / Makino, T. / Shirouzu, M. / Shigematsu, H. / Sekimoto, K. / Gigant, B. / Muto, E. |
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履歴 | 登録 | 2019年11月22日 | 登録サイト: PDBE / 処理サイト: PDBE |
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改定 1.0 | 2021年1月27日 | Provider: repository / タイプ: Initial release |
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改定 1.1 | 2021年2月17日 | Group: Database references / カテゴリ: citation Item: _citation.journal_volume / _citation.pdbx_database_id_PubMed / _citation.title |
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改定 1.2 | 2024年1月24日 | Group: Data collection / Database references / Refinement description カテゴリ: chem_comp_atom / chem_comp_bond ...chem_comp_atom / chem_comp_bond / database_2 / pdbx_initial_refinement_model Item: _database_2.pdbx_DOI / _database_2.pdbx_database_accession |
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