Entry Database : PDB / ID : 6kmb Structure visualization Downloads & linksTitle Crystal structure of Sth1 bromodomain ComponentsNuclear protein STH1/NPS1 Details Keywords GENE REGULATION / Chromatin remodeling / histone acetylation / RSC complex / Sth1 / bromodomainFunction / homology Function and homology informationFunction Domain/homology Component
chromatin remodeling at centromere / DNA translocase activity / RSC-type complex / nucleosome disassembly / ATP-dependent chromatin remodeler activity / chromosome, centromeric region / ATP-dependent activity, acting on DNA / cytoskeleton organization / meiotic cell cycle / helicase activity ... chromatin remodeling at centromere / DNA translocase activity / RSC-type complex / nucleosome disassembly / ATP-dependent chromatin remodeler activity / chromosome, centromeric region / ATP-dependent activity, acting on DNA / cytoskeleton organization / meiotic cell cycle / helicase activity / chromosome segregation / transcription elongation by RNA polymerase II / lysine-acetylated histone binding / base-excision repair / double-strand break repair / DNA helicase / chromatin remodeling / regulation of DNA-templated transcription / chromatin / positive regulation of transcription by RNA polymerase II / ATP hydrolysis activity / DNA binding / ATP binding / nucleus Similarity search - Function Snf2, ATP coupling domain / Snf2-ATP coupling, chromatin remodelling complex / Snf2-ATP coupling, chromatin remodelling complex / HSA domain / Helicase/SANT-associated domain / HSA domain profile. / : / SNF2-like, N-terminal domain superfamily / SNF2, N-terminal / SNF2-related domain ... Snf2, ATP coupling domain / Snf2-ATP coupling, chromatin remodelling complex / Snf2-ATP coupling, chromatin remodelling complex / HSA domain / Helicase/SANT-associated domain / HSA domain profile. / : / SNF2-like, N-terminal domain superfamily / SNF2, N-terminal / SNF2-related domain / Bromodomain-like / Helicase conserved C-terminal domain / Histone Acetyltransferase; Chain A / Bromodomain, conserved site / Bromodomain signature. / Bromodomain / Bromodomain profile. / bromo domain / Bromodomain / Bromodomain-like superfamily / helicase superfamily c-terminal domain / Superfamilies 1 and 2 helicase C-terminal domain profile. / Superfamilies 1 and 2 helicase ATP-binding type-1 domain profile. / DEAD-like helicases superfamily / Helicase, C-terminal / Helicase superfamily 1/2, ATP-binding domain / Up-down Bundle / P-loop containing nucleoside triphosphate hydrolase / Mainly Alpha Similarity search - Domain/homologyBiological species Saccharomyces cerevisiae (brewer's yeast)Method X-RAY DIFFRACTION / SYNCHROTRON / MOLECULAR REPLACEMENT / Resolution : 2.4 Å DetailsAuthors Chen, G. / Li, W. / Yan, F. / Wang, D. / Chen, Y. Funding support China, 1items Details Hide detailsOrganization Grant number Country National Natural Science Foundation of China 31670748 China
CitationJournal : Structure / Year : 2020Title : The Structural Basis for Specific Recognition of H3K14 Acetylation by Sth1 in the RSC Chromatin Remodeling Complex.Authors : Chen, G. / Li, W. / Yan, F. / Wang, D. / Chen, Y. History Deposition Jul 31, 2019 Deposition site : PDBJ / Processing site : PDBJRevision 1.0 Oct 30, 2019 Provider : repository / Type : Initial releaseRevision 1.1 Nov 27, 2019 Group : Database references / Category : citationItem : _citation.pdbx_database_id_DOI / _citation.pdbx_database_id_PubMed / _citation.titleRevision 1.2 Jan 22, 2020 Group : Database references / Category : citationItem : _citation.journal_volume / _citation.page_first / _citation.yearRevision 1.3 Nov 22, 2023 Group : Data collection / Database references / Refinement descriptionCategory : chem_comp_atom / chem_comp_bond ... chem_comp_atom / chem_comp_bond / database_2 / pdbx_initial_refinement_model Item : _database_2.pdbx_DOI / _database_2.pdbx_database_accession
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