- PDB-6jli: Crystal structure of CTLD7 domain of human PLA2R -
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Basic information
Entry
Database: PDB / ID: 6jli
Title
Crystal structure of CTLD7 domain of human PLA2R
Components
Secretory phospholipase A2 receptor
Keywords
IMMUNE SYSTEM / IMN / Epitope / PLA2R / CTLD7
Function / homology
Function and homology information
negative regulation of arachidonate secretion / negative regulation of phospholipase A2 activity / Acyl chain remodelling of PG / Acyl chain remodelling of PC / Acyl chain remodelling of PI / positive regulation of DNA damage response, signal transduction by p53 class mediator / Acyl chain remodelling of PS / Acyl chain remodelling of PE / Synthesis of PA / positive regulation of podocyte apoptotic process ...negative regulation of arachidonate secretion / negative regulation of phospholipase A2 activity / Acyl chain remodelling of PG / Acyl chain remodelling of PC / Acyl chain remodelling of PI / positive regulation of DNA damage response, signal transduction by p53 class mediator / Acyl chain remodelling of PS / Acyl chain remodelling of PE / Synthesis of PA / positive regulation of podocyte apoptotic process / positive regulation of arachidonate secretion / oxidative stress-induced premature senescence / phospholipase binding / replicative senescence / reactive oxygen species metabolic process / receptor-mediated endocytosis / positive regulation of cytokine production / signaling receptor activity / carbohydrate binding / receptor complex / cell surface / extracellular region / plasma membrane Similarity search - Function
Fibronectin type II domain / Fibronectin type II domain superfamily / Fibronectin type II domain / Fibronectin type-II collagen-binding domain signature. / Fibronectin type-II collagen-binding domain profile. / Fibronectin type 2 domain / C-type lectin, conserved site / C-type lectin domain signature. / Ricin-type beta-trefoil / Lectin domain of ricin B chain profile. ...Fibronectin type II domain / Fibronectin type II domain superfamily / Fibronectin type II domain / Fibronectin type-II collagen-binding domain signature. / Fibronectin type-II collagen-binding domain profile. / Fibronectin type 2 domain / C-type lectin, conserved site / C-type lectin domain signature. / Ricin-type beta-trefoil / Lectin domain of ricin B chain profile. / Ricin B, lectin domain / Ricin B-like lectins / C-type lectin domain profile. / C-type lectin-like / C-type lectin (CTL) or carbohydrate-recognition domain (CRD) / Lectin C-type domain / C-type lectin-like/link domain superfamily / C-type lectin fold Similarity search - Domain/homology
Mass: 15319.075 Da / Num. of mol.: 1 Source method: isolated from a genetically manipulated source Details: containing a a conserved N linked Glycosylation site at N1132. Source: (gene. exp.) Homo sapiens (human) / Gene: PLA2R1 / Production host: Trichoplusia ni (cabbage looper) / References: UniProt: Q13018
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