登録情報 | データベース: PDB / ID: 6fql |
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タイトル | Crystal structure of Danio rerio Lin41 filamin-NHL domains in complex with mab-10 3'UTR 13mer RNA |
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要素 | - E3 ubiquitin-protein ligase TRIM71
- RNA (5'-R(*UP*GP*CP*AP*UP*UP*UP*AP*AP*UP*GP*CP*A)-3')
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キーワード | RNA BINDING PROTEIN / post-transcriptional regulation |
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機能・相同性 | 機能・相同性情報
Antigen processing: Ubiquitination & Proteasome degradation / regulation of neural precursor cell proliferation / miRNA-mediated gene silencing by inhibition of translation / neural tube development / miRNA binding / fibroblast growth factor receptor signaling pathway / protein autoubiquitination / stem cell proliferation / P-body / RING-type E3 ubiquitin transferase ...Antigen processing: Ubiquitination & Proteasome degradation / regulation of neural precursor cell proliferation / miRNA-mediated gene silencing by inhibition of translation / neural tube development / miRNA binding / fibroblast growth factor receptor signaling pathway / protein autoubiquitination / stem cell proliferation / P-body / RING-type E3 ubiquitin transferase / G1/S transition of mitotic cell cycle / protein polyubiquitination / ubiquitin-protein transferase activity / ubiquitin protein ligase activity / proteasome-mediated ubiquitin-dependent protein catabolic process / zinc ion binding類似検索 - 分子機能 NHL repeat profile. / NHL repeat / NHL repeat / Filamin/ABP280 repeat / Filamin-type immunoglobulin domains / Filamin/ABP280 repeat / Filamin/ABP280 repeat profile. / Filamin/ABP280 repeat-like / B-box zinc finger / B-Box-type zinc finger ...NHL repeat profile. / NHL repeat / NHL repeat / Filamin/ABP280 repeat / Filamin-type immunoglobulin domains / Filamin/ABP280 repeat / Filamin/ABP280 repeat profile. / Filamin/ABP280 repeat-like / B-box zinc finger / B-Box-type zinc finger / B-box-type zinc finger / Zinc finger B-box type profile. / Six-bladed beta-propeller, TolB-like / Zinc finger, RING-type, conserved site / Zinc finger RING-type signature. / Ring finger / Zinc finger RING-type profile. / Zinc finger, RING-type / Immunoglobulin E-set / Zinc finger, RING/FYVE/PHD-type / Immunoglobulin-like fold類似検索 - ドメイン・相同性 RNA / RNA (> 10) / E3 ubiquitin-protein ligase TRIM71類似検索 - 構成要素 |
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生物種 | ![](img/tx_fish.gif) Danio rerio (ゼブラフィッシュ)
![](img/tx_invertebrata.gif) Caenorhabditis elegans (センチュウ) |
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手法 | X線回折 / シンクロトロン / 分子置換 / 解像度: 2.349 Å |
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データ登録者 | Kumari, P. / Aeschimann, F. / Gaidatzis, D. / Keusch, J.J. / Ghosh, P. / Neagu, A. / Pachulska-Wieczorek, K. / Bujnicki, J.M. / Gut, H. / Grosshans, H. / Ciosk, R. |
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引用 | ジャーナル: Nat Commun / 年: 2018 タイトル: Evolutionary plasticity of the NHL domain underlies distinct solutions to RNA recognition. 著者: Kumari, P. / Aeschimann, F. / Gaidatzis, D. / Keusch, J.J. / Ghosh, P. / Neagu, A. / Pachulska-Wieczorek, K. / Bujnicki, J.M. / Gut, H. / Grosshans, H. / Ciosk, R. |
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履歴 | 登録 | 2018年2月14日 | 登録サイト: PDBE / 処理サイト: PDBE |
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改定 1.0 | 2018年5月9日 | Provider: repository / タイプ: Initial release |
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改定 1.1 | 2024年1月17日 | Group: Data collection / Database references / Refinement description カテゴリ: chem_comp_atom / chem_comp_bond ...chem_comp_atom / chem_comp_bond / database_2 / pdbx_initial_refinement_model Item: _database_2.pdbx_DOI / _database_2.pdbx_database_accession |
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