登録情報 | データベース: PDB / ID: 5zva |
---|
タイトル | APOBEC3F Chimeric Catalytic Domain in Complex with DNA(dC9) |
---|
要素 | - APEBEC3F/ssDNA-C9
- DNA (5'-D(*AP*TP*TP*TP*TP*CP*AP*AP*CP*T)-3')
|
---|
キーワード | STRUCTURAL PROTEIN/DNA / APOBEC3F / HIV-1 / deamination / STRUCTURAL PROTEIN-DNA complex |
---|
機能・相同性 | 機能・相同性情報
apolipoprotein B mRNA editing enzyme complex / dCTP deaminase activity / cytidine deamination / base conversion or substitution editing / single-stranded DNA cytosine deaminase / DNA cytosine deamination / : / cytidine to uridine editing / cytidine deaminase activity / clearance of foreign intracellular DNA ...apolipoprotein B mRNA editing enzyme complex / dCTP deaminase activity / cytidine deamination / base conversion or substitution editing / single-stranded DNA cytosine deaminase / DNA cytosine deamination / : / cytidine to uridine editing / cytidine deaminase activity / clearance of foreign intracellular DNA / negative regulation of viral process / negative regulation of single stranded viral RNA replication via double stranded DNA intermediate / : / positive regulation of gene expression via chromosomal CpG island demethylation / retrotransposon silencing / negative regulation of viral genome replication / APOBEC3G mediated resistance to HIV-1 infection / positive regulation of defense response to virus by host / Vif-mediated degradation of APOBEC3G / P-body / defense response to virus / ribonucleoprotein complex / innate immune response / RNA binding / zinc ion binding / identical protein binding / nucleus / cytoplasm / cytosol類似検索 - 分子機能 Novel AID APOBEC clade 2 / APOBEC/CMP deaminase, zinc-binding / Cytidine and deoxycytidylate deaminases zinc-binding region signature. / Cytidine and deoxycytidylate deaminase domain / Cytidine and deoxycytidylate deaminases domain profile. / Cytidine deaminase-like類似検索 - ドメイン・相同性 CACODYLATE ION / DNA / DNA dC->dU-editing enzyme APOBEC-3F / DNA dC->dU-editing enzyme APOBEC-3G類似検索 - 構成要素 |
---|
生物種 | Homo sapiens (ヒト) DNA-binding vector pODB80 (その他) |
---|
手法 | X線回折 / シンクロトロン / 単波長異常分散 / 解像度: 2.3 Å |
---|
データ登録者 | Cheng, C. / Zhang, T.L. / Wang, C.X. / Lan, W.X. / Ding, J.P. / Cao, C.Y. |
---|
資金援助 | 中国, 1件 組織 | 認可番号 | 国 |
---|
National Science Foundation (China) | 91753119, 21778065 and 21472229 | 中国 |
|
---|
引用 | ジャーナル: Chin.J.Chem. / 年: 2018 タイトル: Crystal Structure of Cytidine Deaminase Human APOBEC3F Chimeric Catalytic Domain in Complex with DNA 著者: Cheng, C. / Zhang, T. / Wang, C. / Lan, W. / Ding, J. / Cao, C. |
---|
履歴 | 登録 | 2018年5月9日 | 登録サイト: PDBJ / 処理サイト: PDBJ |
---|
改定 1.0 | 2018年11月21日 | Provider: repository / タイプ: Initial release |
---|
改定 1.1 | 2018年11月28日 | Group: Data collection / Database references / Structure summary カテゴリ: citation / entity / struct Item: _citation.journal_volume / _citation.pdbx_database_id_DOI ..._citation.journal_volume / _citation.pdbx_database_id_DOI / _citation.title / _entity.pdbx_description / _struct.pdbx_descriptor / _struct.title |
---|
|
---|