登録情報 | データベース: PDB / ID: 5ykp |
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タイトル | Human methionine aminopeptidase type 1b (F309M mutant) in complex with ovalicin |
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要素 | Methionine aminopeptidase 1 |
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キーワード | METAL BINDING PROTEIN / selective inhibition / Streptococcal pneumoniae / Enterococcus feacalis |
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機能・相同性 | 機能・相同性情報
N-terminal protein amino acid modification / peptidyl-methionine modification / initiator methionyl aminopeptidase activity / methionyl aminopeptidase / metalloexopeptidase activity / metalloaminopeptidase activity / protein maturation / aminopeptidase activity / platelet aggregation / Inactivation, recovery and regulation of the phototransduction cascade ...N-terminal protein amino acid modification / peptidyl-methionine modification / initiator methionyl aminopeptidase activity / methionyl aminopeptidase / metalloexopeptidase activity / metalloaminopeptidase activity / protein maturation / aminopeptidase activity / platelet aggregation / Inactivation, recovery and regulation of the phototransduction cascade / regulation of translation / proteolysis / metal ion binding / cytosol / cytoplasm類似検索 - 分子機能 Zinc finger C6H2-type profile. / MYND-like zinc finger / zf-MYND-like zinc finger, mRNA-binding / Methionine aminopeptidase subfamily 1 signature. / Peptidase M24A, methionine aminopeptidase, subfamily 1 / Peptidase M24, methionine aminopeptidase / Creatine Amidinohydrolase / Creatinase/methionine aminopeptidase superfamily / Peptidase M24 / Metallopeptidase family M24 ...Zinc finger C6H2-type profile. / MYND-like zinc finger / zf-MYND-like zinc finger, mRNA-binding / Methionine aminopeptidase subfamily 1 signature. / Peptidase M24A, methionine aminopeptidase, subfamily 1 / Peptidase M24, methionine aminopeptidase / Creatine Amidinohydrolase / Creatinase/methionine aminopeptidase superfamily / Peptidase M24 / Metallopeptidase family M24 / Creatinase/aminopeptidase-like / Alpha-Beta Complex / Alpha Beta類似検索 - ドメイン・相同性 : / : / Chem-OVA / Methionine aminopeptidase 1類似検索 - 構成要素 |
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生物種 | Homo sapiens (ヒト) |
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手法 | X線回折 / 分子置換 / 解像度: 1.68 Å |
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データ登録者 | Arya, T. / Pillalamarri, V. / Addlagatta, A. |
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資金援助 | インド, 1件 組織 | 認可番号 | 国 |
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Department of Science and Technology | EMR/2015/000461 | インド |
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引用 | ジャーナル: Biochem. J. / 年: 2019 タイトル: Discovery of natural product ovalicin sensitive type 1 methionine aminopeptidases: molecular and structural basis. 著者: Pillalamarri, V. / Arya, T. / Haque, N. / Bala, S.C. / Marapaka, A.K. / Addlagatta, A. |
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履歴 | 登録 | 2017年10月15日 | 登録サイト: PDBJ / 処理サイト: PDBJ |
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改定 1.0 | 2018年10月17日 | Provider: repository / タイプ: Initial release |
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改定 1.1 | 2019年3月20日 | Group: Advisory / Data collection ...Advisory / Data collection / Database references / Derived calculations カテゴリ: citation / citation_author ...citation / citation_author / pdbx_validate_close_contact / struct_conn / struct_conn_type Item: _citation.country / _citation.journal_abbrev ..._citation.country / _citation.journal_abbrev / _citation.journal_id_ASTM / _citation.journal_id_CSD / _citation.journal_id_ISSN / _citation.pdbx_database_id_DOI / _citation.pdbx_database_id_PubMed / _citation.title / _citation.year |
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改定 1.2 | 2019年4月3日 | Group: Data collection / Database references / カテゴリ: citation / citation_author Item: _citation.journal_volume / _citation.page_first ..._citation.journal_volume / _citation.page_first / _citation.page_last / _citation.title / _citation_author.identifier_ORCID |
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改定 1.3 | 2023年11月22日 | Group: Data collection / Database references ...Data collection / Database references / Derived calculations / Refinement description カテゴリ: chem_comp_atom / chem_comp_bond ...chem_comp_atom / chem_comp_bond / database_2 / pdbx_initial_refinement_model / struct_conn Item: _database_2.pdbx_DOI / _database_2.pdbx_database_accession ..._database_2.pdbx_DOI / _database_2.pdbx_database_accession / _struct_conn.pdbx_dist_value / _struct_conn.ptnr1_label_atom_id / _struct_conn.ptnr2_auth_seq_id / _struct_conn.ptnr2_label_asym_id |
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