登録情報 データベース : PDB / ID : 5lmg 構造の表示 ダウンロードとリンクタイトル Structure of C-terminal domain from S. cerevisiae Pat1 decapping activator bound to Dcp2 HLM10 peptide (region 954-970) 要素DNA topoisomerase 2-associated protein PAT1 mRNA decapping protein 2 詳細キーワード RNA BINDING PROTEIN / Protein peptide complex / ISOMERASE機能・相同性 機能・相同性情報分子機能 ドメイン・相同性 構成要素
RNA decapping complex / Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA / Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA / deadenylation-independent decapping of nuclear-transcribed mRNA / mRNA 5'-diphosphatase activity / mRNA decay by 5' to 3' exoribonuclease / 5'-(N7-methylguanosine 5'-triphospho)-[mRNA] hydrolase / Lsm1-7-Pat1 complex / 5'-(N(7)-methylguanosine 5'-triphospho)-[mRNA] hydrolase activity / cytoplasmic side of membrane ... RNA decapping complex / Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA / Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA / deadenylation-independent decapping of nuclear-transcribed mRNA / mRNA 5'-diphosphatase activity / mRNA decay by 5' to 3' exoribonuclease / 5'-(N7-methylguanosine 5'-triphospho)-[mRNA] hydrolase / Lsm1-7-Pat1 complex / 5'-(N(7)-methylguanosine 5'-triphospho)-[mRNA] hydrolase activity / cytoplasmic side of membrane / deadenylation-dependent decapping of nuclear-transcribed mRNA / formation of translation preinitiation complex / P-body assembly / regulation of translational initiation / nuclear-transcribed mRNA catabolic process, nonsense-mediated decay / positive regulation of transcription initiation by RNA polymerase II / cellular response to glucose starvation / stress granule assembly / negative regulation of translational initiation / P-body / kinetochore / cytoplasmic stress granule / mRNA processing / manganese ion binding / cytosolic small ribosomal subunit / hydrolase activity / cell division / mRNA binding / chromatin binding / RNA binding / nucleus / cytoplasm 類似検索 - 分子機能 mRNA decay factor PAT1 domain / Pat1-like / Topoisomerase II-associated protein PAT1 / mRNA decapping protein 2, Box A domain / mRNA decapping protein 2, Box A domain superfamily / mRNA decapping enzyme 2 , NUDIX hydrolase domain / Dcp2, box A domain / Dcp2, box A domain / NUDIX hydrolase, conserved site / Nudix box signature. ... mRNA decay factor PAT1 domain / Pat1-like / Topoisomerase II-associated protein PAT1 / mRNA decapping protein 2, Box A domain / mRNA decapping protein 2, Box A domain superfamily / mRNA decapping enzyme 2 , NUDIX hydrolase domain / Dcp2, box A domain / Dcp2, box A domain / NUDIX hydrolase, conserved site / Nudix box signature. / NUDIX domain / Nudix hydrolase domain profile. / NUDIX hydrolase domain / NUDIX hydrolase-like domain superfamily 類似検索 - ドメイン・相同性 mRNA decapping protein 2 / Deadenylation-dependent mRNA-decapping factor PAT1 / m7GpppN-mRNA hydrolase 類似検索 - 構成要素生物種 Saccharomyces cerevisiae (パン酵母)手法 X線回折 / シンクロトロン / 分子置換 / 解像度 : 1.89 Å 詳細データ登録者 Charenton, C. / Gaudon-Plesse, C. / Fourati, Z. / Taverniti, V. / Back, R. / Kolesnikova, O. / Seraphin, B. / Graille, M. 引用ジャーナル : Proc. Natl. Acad. Sci. U.S.A. / 年 : 2017タイトル : A unique surface on Pat1 C-terminal domain directly interacts with Dcp2 decapping enzyme and Xrn1 5'-3' mRNA exonuclease in yeast.著者 : Charenton, C. / Gaudon-Plesse, C. / Fourati, Z. / Taverniti, V. / Back, R. / Kolesnikova, O. / Seraphin, B. / Graille, M. 履歴 登録 2016年7月30日 登録サイト : PDBE / 処理サイト : PDBE改定 1.0 2017年8月16日 Provider : repository / タイプ : Initial release改定 1.1 2017年11月1日 Group : Database references / カテゴリ : citation / Item : _citation.title改定 1.2 2017年11月8日 Group : Database references / カテゴリ : citationItem : _citation.journal_abbrev / _citation.pdbx_database_id_PubMed改定 1.3 2017年11月15日 Group : Database references / カテゴリ : citationItem : _citation.journal_volume / _citation.page_first / _citation.page_last改定 1.4 2018年9月26日 Group : Data collection / Structure summary / カテゴリ : struct / Item : _struct.title改定 1.5 2024年1月10日 Group : Data collection / Database references ... Data collection / Database references / Derived calculations / Refinement description カテゴリ : chem_comp_atom / chem_comp_bond ... chem_comp_atom / chem_comp_bond / database_2 / pdbx_initial_refinement_model / pdbx_struct_conn_angle / struct_conn Item : _database_2.pdbx_DOI / _database_2.pdbx_database_accession ... _database_2.pdbx_DOI / _database_2.pdbx_database_accession / _pdbx_struct_conn_angle.ptnr1_auth_comp_id / _pdbx_struct_conn_angle.ptnr1_auth_seq_id / _pdbx_struct_conn_angle.ptnr1_label_asym_id / _pdbx_struct_conn_angle.ptnr1_label_atom_id / _pdbx_struct_conn_angle.ptnr1_label_comp_id / _pdbx_struct_conn_angle.ptnr1_label_seq_id / _pdbx_struct_conn_angle.ptnr1_symmetry / _pdbx_struct_conn_angle.ptnr3_auth_comp_id / _pdbx_struct_conn_angle.ptnr3_auth_seq_id / _pdbx_struct_conn_angle.ptnr3_label_asym_id / _pdbx_struct_conn_angle.ptnr3_label_atom_id / _pdbx_struct_conn_angle.ptnr3_label_comp_id / _pdbx_struct_conn_angle.ptnr3_label_seq_id / _pdbx_struct_conn_angle.ptnr3_symmetry / _pdbx_struct_conn_angle.value / _struct_conn.pdbx_dist_value / _struct_conn.ptnr1_auth_comp_id / _struct_conn.ptnr1_auth_seq_id / _struct_conn.ptnr1_label_asym_id / _struct_conn.ptnr1_label_atom_id / _struct_conn.ptnr1_label_comp_id / _struct_conn.ptnr1_label_seq_id / _struct_conn.ptnr2_auth_comp_id / _struct_conn.ptnr2_auth_seq_id / _struct_conn.ptnr2_label_asym_id / _struct_conn.ptnr2_label_atom_id / _struct_conn.ptnr2_label_comp_id / _struct_conn.ptnr2_symmetry
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