登録情報 データベース : PDB / ID : 5iuq 構造の表示 ダウンロードとリンクタイトル Galectin-3c in complex with Bisamido-thiogalactoside derivative 4 要素Galectin-3 詳細 キーワード SUGAR BINDING PROTEIN / Gal3C / CRD機能・相同性 機能・相同性情報分子機能 ドメイン・相同性 構成要素
: / negative regulation of immunological synapse formation / disaccharide binding / negative regulation of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell / RUNX2 regulates genes involved in differentiation of myeloid cells / regulation of T cell apoptotic process / mononuclear cell migration / positive regulation of mononuclear cell migration / negative regulation of endocytosis / IgE binding ... : / negative regulation of immunological synapse formation / disaccharide binding / negative regulation of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell / RUNX2 regulates genes involved in differentiation of myeloid cells / regulation of T cell apoptotic process / mononuclear cell migration / positive regulation of mononuclear cell migration / negative regulation of endocytosis / IgE binding / eosinophil chemotaxis / regulation of extrinsic apoptotic signaling pathway via death domain receptors / RUNX1 regulates transcription of genes involved in differentiation of myeloid cells / protein phosphatase inhibitor activity / negative regulation of T cell receptor signaling pathway / regulation of T cell proliferation / positive chemotaxis / macrophage chemotaxis / positive regulation of calcium ion import / chemoattractant activity / monocyte chemotaxis / Advanced glycosylation endproduct receptor signaling / ficolin-1-rich granule membrane / immunological synapse / laminin binding / epithelial cell differentiation / neutrophil chemotaxis / RNA splicing / secretory granule membrane / molecular condensate scaffold activity / negative regulation of extrinsic apoptotic signaling pathway / positive regulation of protein localization to plasma membrane / spliceosomal complex / positive regulation of protein-containing complex assembly / mRNA processing / carbohydrate binding / protein phosphatase binding / collagen-containing extracellular matrix / mitochondrial inner membrane / innate immune response / Neutrophil degranulation / cell surface / RNA binding / extracellular space / extracellular exosome / extracellular region / nucleoplasm / membrane / nucleus / plasma membrane / cytosol / cytoplasm 類似検索 - 分子機能 Galectin-like / Galactoside-binding lectin / Galectin / Galectin, carbohydrate recognition domain / Galactoside-binding lectin / Galactoside-binding lectin (galectin) domain profile. / Jelly Rolls - #200 / Concanavalin A-like lectin/glucanase domain superfamily / Jelly Rolls / Sandwich / Mainly Beta 類似検索 - ドメイン・相同性生物種 Homo sapiens (ヒト)手法 X線回折 / シンクロトロン / 分子置換 / 解像度 : 1.121 Å 詳細データ登録者 Noresson, A.-L. / Aurelius, O. / Oberg, C.T. / Engstrom, O. / Sundin, A.P. / Hakansson, M. / Logan, D.T. / Leffler, H. / Nilsson, U.J. 資金援助 スウェーデン, 5件 詳細 詳細を隠す組織 認可番号 国 Swedish Research Council 621-2009-5326 スウェーデン Swedish Research Council 621-2012-2978 スウェーデン Olle Engkvist Byggmastare foundation スウェーデン Royal Physiographic Society スウェーデン European Community's Seventh Framework Program (FP7-2007-2013) HEALTH F2-2011-256986 project acronym PANACREAS
引用ジャーナル : To Be Published タイトル : Controlling protein:ligand complex conformation through tuning of arginine-arene interactions: Synthetic and structural studies with 3-benzamido-2-sulfo-galactosides as galectin-3 ligands著者 : Noresson, A.-L. / Aurelius, O. / Oberg, C.T. / Engstrom, O. / Sundin, A.P. / Hakansson, M. / Logan, D. / Leffler, H. / Nilsson, U.J. 履歴 登録 2016年3月18日 登録サイト : RCSB / 処理サイト : PDBE改定 1.0 2017年3月29日 Provider : repository / タイプ : Initial release改定 1.1 2018年1月17日 Group : Data collection / カテゴリ : diffrn_source / Item : _diffrn_source.pdbx_synchrotron_site改定 1.2 2024年1月10日 Group : Data collection / Database references / Refinement descriptionカテゴリ : chem_comp_atom / chem_comp_bond ... chem_comp_atom / chem_comp_bond / database_2 / pdbx_initial_refinement_model Item : _database_2.pdbx_DOI / _database_2.pdbx_database_accession
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