- PDB-5itt: Crystal Structure of Human NEIL1 bound to duplex DNA containing THF -
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基本情報
登録情報
データベース: PDB / ID: 5itt
タイトル
Crystal Structure of Human NEIL1 bound to duplex DNA containing THF
要素
(DNA (26-MER)) x 2
Endonuclease 8-like 1
キーワード
DNA BINDING PROTEIN/DNA / NEIL1 DNA Glycosylase base excision repair Fpg Nei / DNA BINDING PROTEIN-DNA complex
機能・相同性
機能・相同性情報
negative regulation of nuclease activity / Defective Base Excision Repair Associated with NEIL1 / depyrimidination / DNA N-glycosylase activity / hydrolase activity, acting on glycosyl bonds / 加水分解酵素; 糖加水分解酵素; N-グリコシル化合物加水分解酵素 / APEX1-Independent Resolution of AP Sites via the Single Nucleotide Replacement Pathway / Recognition and association of DNA glycosylase with site containing an affected pyrimidine / Cleavage of the damaged pyrimidine / DNA-(apurinic or apyrimidinic site) endonuclease activity ...negative regulation of nuclease activity / Defective Base Excision Repair Associated with NEIL1 / depyrimidination / DNA N-glycosylase activity / hydrolase activity, acting on glycosyl bonds / 加水分解酵素; 糖加水分解酵素; N-グリコシル化合物加水分解酵素 / APEX1-Independent Resolution of AP Sites via the Single Nucleotide Replacement Pathway / Recognition and association of DNA glycosylase with site containing an affected pyrimidine / Cleavage of the damaged pyrimidine / DNA-(apurinic or apyrimidinic site) endonuclease activity / class I DNA-(apurinic or apyrimidinic site) endonuclease activity / DNA-(apurinic or apyrimidinic site) lyase / base-excision repair, gap-filling / base-excision repair / chromosome / response to oxidative stress / damaged DNA binding / centrosome / zinc ion binding / nucleoplasm / nucleus / cytoplasm / cytosol 類似検索 - 分子機能