- PDB-5crv: Crystal structure of the Bro domain of HD-PTP in a complex with t... -
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基本情報
登録情報
データベース: PDB / ID: 5crv
タイトル
Crystal structure of the Bro domain of HD-PTP in a complex with the core region of STAM2
要素
Signal transducing adapter molecule 2
Tyrosine-protein phosphatase non-receptor type 23
キーワード
PROTEIN TRANSPORT / HD-PTP / Bro domain / STAM2 / ESCRT-0 / EGFR
機能・相同性
機能・相同性情報
positive regulation of homophilic cell adhesion / positive regulation of adherens junction organization / ESCRT-0 complex / positive regulation of Wnt protein secretion / positive regulation of early endosome to late endosome transport / negative regulation of epithelial cell migration / protein transport to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway / membrane fission / early endosome to late endosome transport / ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway ...positive regulation of homophilic cell adhesion / positive regulation of adherens junction organization / ESCRT-0 complex / positive regulation of Wnt protein secretion / positive regulation of early endosome to late endosome transport / negative regulation of epithelial cell migration / protein transport to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway / membrane fission / early endosome to late endosome transport / ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway / multivesicular body assembly / endocytic recycling / Interleukin-37 signaling / RHOU GTPase cycle / endocytic vesicle / cilium assembly / dephosphorylation / Endosomal Sorting Complex Required For Transport (ESCRT) / phosphatidylinositol binding / protein-tyrosine-phosphatase / InlB-mediated entry of Listeria monocytogenes into host cell / ciliary basal body / ubiquitin binding / protein tyrosine phosphatase activity / macroautophagy / EGFR downregulation / Negative regulation of MET activity / Cargo recognition for clathrin-mediated endocytosis / Clathrin-mediated endocytosis / early endosome membrane / early endosome / nuclear body / Ub-specific processing proteases / endosome / intracellular membrane-bounded organelle / protein kinase binding / signal transduction / extracellular exosome / nucleoplasm / nucleus / cytoplasm / cytosol 類似検索 - 分子機能
: / STAM2, SH3 domain / alix/aip1 like domains / Vacuolar protein-sorting protein Bro1-like / ALIX V-shaped domain / ALIX V-shaped domain binding to HIV / BRO1 domain / BRO1 domain superfamily / BRO1-like domain / BRO1 domain profile. ...: / STAM2, SH3 domain / alix/aip1 like domains / Vacuolar protein-sorting protein Bro1-like / ALIX V-shaped domain / ALIX V-shaped domain binding to HIV / BRO1 domain / BRO1 domain superfamily / BRO1-like domain / BRO1 domain profile. / BRO1-like domain / VHS domain / VHS domain / VHS domain profile. / Domain present in VPS-27, Hrs and STAM / Ubiquitin interaction motif / ENTH/VHS / Ubiquitin-interacting motif. / Ubiquitin interacting motif / Ubiquitin-interacting motif (UIM) domain profile. / Protein tyrosine phosphatase, catalytic domain / PTP type protein phosphatase domain profile. / Protein-tyrosine phosphatase / Tyrosine-specific protein phosphatase, PTPase domain / Protein-tyrosine phosphatase, catalytic / Protein tyrosine phosphatase, catalytic domain motif / Tyrosine specific protein phosphatases active site. / Protein-tyrosine phosphatase, active site / Tyrosine-specific protein phosphatases domain / Tyrosine specific protein phosphatases domain profile. / Protein-tyrosine phosphatase-like / SH3 domain / Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat / Src homology 3 domains / SH3-like domain superfamily / Src homology 3 (SH3) domain profile. / SH3 domain / Alpha Horseshoe / Mainly Alpha 類似検索 - ドメイン・相同性
Signal transducing adapter molecule 2 / Tyrosine-protein phosphatase non-receptor type 23 類似検索 - 構成要素