Entry | Database: PDB / ID: 5c98 |
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Title | 1.45A resolution structure of SRPN18 from Anopheles gambiae |
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Components | AGAP007691-PB |
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Keywords | UNKNOWN FUNCTION / serpin / serine protease / insect immunity / enzyme inhibitor |
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Function / homology | Function and homology information
negative regulation of endopeptidase activity / serine-type endopeptidase inhibitor activity / extracellular spaceSimilarity search - Function Leukocyte elastase inhibitor (serpin B1) / Antithrombin; Chain I, domain 2 / Antithrombin, subunit I, domain 2 / Alpha-1-antitrypsin; domain 1 / Alpha-1-antitrypsin, domain 1 / Serpin, conserved site / Serpins signature. / Serpin superfamily, domain 2 / Serpin family / Serpin domain ...Leukocyte elastase inhibitor (serpin B1) / Antithrombin; Chain I, domain 2 / Antithrombin, subunit I, domain 2 / Alpha-1-antitrypsin; domain 1 / Alpha-1-antitrypsin, domain 1 / Serpin, conserved site / Serpins signature. / Serpin superfamily, domain 2 / Serpin family / Serpin domain / Serpin superfamily / Serpin superfamily, domain 1 / Serpin (serine protease inhibitor) / SERine Proteinase INhibitors / Roll / 2-Layer Sandwich / Mainly Beta / Alpha BetaSimilarity search - Domain/homology |
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Biological species | Anopheles gambiae (African malaria mosquito) |
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Method | X-RAY DIFFRACTION / SYNCHROTRON / MOLECULAR REPLACEMENT / molecular replacement / Resolution: 1.45 Å |
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Authors | Lovell, S. / Battaile, K.P. / Gulley, M. / Zhang, X. / Meekins, D.A. / Gao, F.P. / Michel, K. |
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Funding support | United States, 1items Organization | Grant number | Country |
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National Institutes of Health/National Institute Of Allergy and Infectious Diseases (NIH/NIAID) | 5R01AI095842 | United States |
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Citation | Journal: Acta Crystallogr F Struct Biol Commun / Year: 2016 Title: 1.45 angstrom resolution structure of SRPN18 from the malaria vector Anopheles gambiae. Authors: Meekins, D.A. / Zhang, X. / Battaile, K.P. / Lovell, S. / Michel, K. |
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History | Deposition | Jun 26, 2015 | Deposition site: RCSB / Processing site: RCSB |
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Revision 1.0 | Sep 14, 2016 | Provider: repository / Type: Initial release |
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Revision 1.1 | Dec 14, 2016 | Group: Database references |
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Revision 1.2 | Sep 13, 2017 | Group: Author supporting evidence / Category: pdbx_audit_support / Item: _pdbx_audit_support.funding_organization |
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Revision 1.3 | Dec 11, 2019 | Group: Author supporting evidence / Category: pdbx_audit_support / Item: _pdbx_audit_support.funding_organization |
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Revision 1.4 | Sep 27, 2023 | Group: Data collection / Database references / Refinement description Category: chem_comp_atom / chem_comp_bond ...chem_comp_atom / chem_comp_bond / database_2 / pdbx_initial_refinement_model Item: _database_2.pdbx_DOI / _database_2.pdbx_database_accession |
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