- PDB-5b8c: High resolution structure of the human PD-1 in complex with pembr... -
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IDまたはキーワード:
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基本情報
登録情報
データベース: PDB / ID: 5b8c
タイトル
High resolution structure of the human PD-1 in complex with pembrolizumab Fv
要素
Pembrolizumab heavy chain variable region (PemVH)
Pembrolizumab light chain variable region (PemVL)
Programmed cell death protein 1
キーワード
IMMUNE SYSTEM / antibody
機能・相同性
機能・相同性情報
negative regulation of tolerance induction / regulatory T cell apoptotic process / negative regulation of immune response / negative regulation of T cell mediated immune response to tumor cell / negative regulation of T cell activation / positive regulation of T cell apoptotic process / B cell apoptotic process / negative regulation of B cell apoptotic process / humoral immune response / Co-inhibition by PD-1 ...negative regulation of tolerance induction / regulatory T cell apoptotic process / negative regulation of immune response / negative regulation of T cell mediated immune response to tumor cell / negative regulation of T cell activation / positive regulation of T cell apoptotic process / B cell apoptotic process / negative regulation of B cell apoptotic process / humoral immune response / Co-inhibition by PD-1 / regulation of immune response / signaling receptor activity / adaptive immune response / Potential therapeutics for SARS / external side of plasma membrane / apoptotic process / plasma membrane 類似検索 - 分子機能
A: Pembrolizumab light chain variable region (PemVL) B: Pembrolizumab heavy chain variable region (PemVH) C: Programmed cell death protein 1 D: Pembrolizumab light chain variable region (PemVL) E: Pembrolizumab heavy chain variable region (PemVH) F: Programmed cell death protein 1 G: Pembrolizumab light chain variable region (PemVL) H: Pembrolizumab heavy chain variable region (PemVH) I: Programmed cell death protein 1 J: Pembrolizumab light chain variable region (PemVL) K: Pembrolizumab heavy chain variable region (PemVH) L: Programmed cell death protein 1