TBK1 recruitment to cytosol-invading Salmonella induces anti- bacterial autophagy
Components
OPTINEURIN
Keywords
PROTEIN BINDING
Function / homology
Function and homology information
parkin-mediated stimulation of mitophagy in response to mitochondrial depolarization / cell death / negative regulation of receptor recycling / Golgi ribbon formation / protein localization to Golgi apparatus / positive regulation of xenophagy / Golgi to plasma membrane protein transport / TBC/RABGAPs / regulation of canonical NF-kappaB signal transduction / TNFR1-induced proapoptotic signaling ...parkin-mediated stimulation of mitophagy in response to mitochondrial depolarization / cell death / negative regulation of receptor recycling / Golgi ribbon formation / protein localization to Golgi apparatus / positive regulation of xenophagy / Golgi to plasma membrane protein transport / TBC/RABGAPs / regulation of canonical NF-kappaB signal transduction / TNFR1-induced proapoptotic signaling / K63-linked polyubiquitin modification-dependent protein binding / Golgi organization / autophagosome / polyubiquitin modification-dependent protein binding / cellular response to unfolded protein / positive regulation of autophagy / negative regulation of canonical NF-kappaB signal transduction / Regulation of TBK1, IKKε (IKBKE)-mediated activation of IRF3, IRF7 / Regulation of TBK1, IKKε-mediated activation of IRF3, IRF7 upon TLR3 ligation / TICAM1-dependent activation of IRF3/IRF7 / Activation of IRF3, IRF7 mediated by TBK1, IKKε (IKBKE) / TNFR1-induced NF-kappa-B signaling pathway / Regulation of TNFR1 signaling / trans-Golgi network / autophagy / recycling endosome membrane / Regulation of PLK1 Activity at G2/M Transition / protein-macromolecule adaptor activity / defense response to Gram-negative bacterium / Golgi membrane / innate immune response / perinuclear region of cytoplasm / Golgi apparatus / signal transduction / nucleoplasm / identical protein binding / nucleus / metal ion binding / cytoplasm / cytosol Similarity search - Function
OPTINEURIN / E3-14.7K-INTERACTING PROTEIN / FIP-2 / HUNTINGTIN YEAST PARTNER L / HUNTINGTIN-INTERACTING PROTEIN ...E3-14.7K-INTERACTING PROTEIN / FIP-2 / HUNTINGTIN YEAST PARTNER L / HUNTINGTIN-INTERACTING PROTEIN 7 / HIP-7 / HUNTINGTIN-INTERACTING PROTEIN L / NEMO-RELATED PROTEIN / OPTIC NEUROPATHY-INDUCING PROTEIN / TRANSCRIPTION FACTOR IIIA-INTERACTING PROTEIN / TFIIIA-INTP
Mass: 3522.147 Da / Num. of mol.: 1 / Fragment: RESIDES 548-577 Source method: isolated from a genetically manipulated source Source: (gene. exp.) HOMO SAPIENS (human) / Plasmid: HLTV PLASMID / Production host: ESCHERICHIA COLI (E. coli) / Strain (production host): BL21(DE3) / Variant (production host): C41 / References: UniProt: Q96CV9
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