登録情報 | データベース: PDB / ID: 4wqn |
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タイトル | Crystal structure of N6-methyladenosine RNA reader YTHDF2 |
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要素 | YTH domain-containing family protein 2 |
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キーワード | RNA BINDING PROTEIN / N6-methyladenosine RNA reader |
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機能・相同性 | 機能・相同性情報
C5-methylcytidine-containing RNA reader activity / organelle assembly / spermatogonial cell division / regulation of meiotic cell cycle process involved in oocyte maturation / regulation of rRNA processing / positive regulation of cap-independent translational initiation / endothelial to hematopoietic transition / gamete generation / embryonic morphogenesis / N6-methyladenosine-containing RNA reader activity ...C5-methylcytidine-containing RNA reader activity / organelle assembly / spermatogonial cell division / regulation of meiotic cell cycle process involved in oocyte maturation / regulation of rRNA processing / positive regulation of cap-independent translational initiation / endothelial to hematopoietic transition / gamete generation / embryonic morphogenesis / N6-methyladenosine-containing RNA reader activity / negative regulation of stem cell differentiation / regulation of hematopoietic stem cell differentiation / oocyte maturation / hematopoietic stem cell proliferation / negative regulation of type I interferon-mediated signaling pathway / mRNA destabilization / negative regulation of Notch signaling pathway / mRNA catabolic process / humoral immune response / centriolar satellite / regulation of neurogenesis / regulation of cell adhesion / stress granule assembly / regulation of mRNA stability / P-body / cytoplasmic stress granule / cytoplasmic ribonucleoprotein granule / innate immune response / mRNA binding / RNA binding / nucleus / cytosol / cytoplasm類似検索 - 分子機能 ph1033 like fold / ph1033 like domains / YTH domain containing protein / YTH domain / YT521-B-like domain / YTH domain profile. / Roll / Alpha Beta類似検索 - ドメイン・相同性 |
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生物種 | Homo sapiens (ヒト) |
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手法 | X線回折 / シンクロトロン / 分子置換 / 解像度: 2.121 Å |
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データ登録者 | Zhu, T. / Roundtree, I.A. / Wang, P. / Wang, X. / Wang, L. / Sun, C. / Tian, Y. / Li, J. / He, C. / Xu, Y. |
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引用 | ジャーナル: Cell Res. / 年: 2014 タイトル: Crystal structure of the YTH domain of YTHDF2 reveals mechanism for recognition of N6-methyladenosine. 著者: Zhu, T. / Roundtree, I.A. / Wang, P. / Wang, X. / Wang, L. / Sun, C. / Tian, Y. / Li, J. / He, C. / Xu, Y. |
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履歴 | 登録 | 2014年10月22日 | 登録サイト: RCSB / 処理サイト: PDBJ |
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改定 1.0 | 2014年11月19日 | Provider: repository / タイプ: Initial release |
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改定 1.1 | 2014年12月10日 | Group: Database references |
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改定 1.2 | 2023年11月8日 | Group: Data collection / Database references ...Data collection / Database references / Derived calculations / Other / Refinement description / Source and taxonomy カテゴリ: chem_comp_atom / chem_comp_bond ...chem_comp_atom / chem_comp_bond / database_2 / entity_src_gen / pdbx_database_status / pdbx_initial_refinement_model / pdbx_struct_oper_list Item: _database_2.pdbx_DOI / _database_2.pdbx_database_accession ..._database_2.pdbx_DOI / _database_2.pdbx_database_accession / _entity_src_gen.pdbx_alt_source_flag / _pdbx_database_status.pdb_format_compatible / _pdbx_struct_oper_list.symmetry_operation |
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