登録情報 | データベース: PDB / ID: 4tq1 |
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タイトル | Crystal structure of human ATG5-TECAIR |
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要素 | - Autophagy protein 5
- Tectonin beta-propeller repeat-containing protein 1
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キーワード | PROTEIN BINDING / autophagy protein complex |
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機能・相同性 | 機能・相同性情報
otolith development / regulation of autophagosome maturation / positive regulation of viral translation / response to fluoride / regulation of cytokine production involved in immune response / Atg8-family ligase activity / Atg12-Atg5-Atg16 complex / antigen processing and presentation of endogenous antigen / phagophore / negative regulation of defense response to virus ...otolith development / regulation of autophagosome maturation / positive regulation of viral translation / response to fluoride / regulation of cytokine production involved in immune response / Atg8-family ligase activity / Atg12-Atg5-Atg16 complex / antigen processing and presentation of endogenous antigen / phagophore / negative regulation of defense response to virus / cellular response to nitrosative stress / ventricular cardiac muscle cell development / positive regulation of stress granule assembly / negative regulation of autophagic cell death / regulation of cilium assembly / mitochondria-associated endoplasmic reticulum membrane contact site / aggrephagy / mucus secretion / response to fungus / transferase complex / negative thymic T cell selection / phagophore assembly site membrane / piecemeal microautophagy of the nucleus / cellular response to nitrogen starvation / regulation of release of sequestered calcium ion into cytosol / phosphatidylinositol-3-phosphate binding / negative stranded viral RNA replication / response to iron(II) ion / negative regulation of phagocytosis / positive regulation of mucus secretion / negative regulation of type I interferon production / negative regulation of cardiac muscle cell apoptotic process / chaperone-mediated autophagy / Macroautophagy / Receptor Mediated Mitophagy / heart contraction / axoneme / autophagosome membrane / mitophagy / autophagosome maturation / autophagosome assembly / autophagosome / negative regulation of reactive oxygen species metabolic process / blood vessel remodeling / negative regulation of protein ubiquitination / cardiac muscle cell apoptotic process / PINK1-PRKN Mediated Mitophagy / negative regulation of innate immune response / post-translational protein modification / establishment of localization in cell / Negative regulators of DDX58/IFIH1 signaling / macroautophagy / autophagy / vasodilation / phagocytic vesicle membrane / chromatin organization / cytoplasmic vesicle / protein ubiquitination / response to xenobiotic stimulus / lysosomal membrane / axon / intracellular membrane-bounded organelle / protein-containing complex / nucleoplasm / membrane / cytoplasm / cytosol類似検索 - 分子機能 Peroxin domain / Integral peroxisomal membrane peroxin / Propeller / Tectonin domain / Autophagy protein Apg5, helix rich domain / Ubiquitin-like (UB roll) - #620 / Peroxin/Ferlin domain / : / : / : ...Peroxin domain / Integral peroxisomal membrane peroxin / Propeller / Tectonin domain / Autophagy protein Apg5, helix rich domain / Ubiquitin-like (UB roll) - #620 / Peroxin/Ferlin domain / : / : / : / Autophagy protein ATG5, alpha-helical bundle region / Autophagy protein ATG5, UblA domain / Dysferlin domain, N-terminal region. / Dysferlin domain, C-terminal region. / Autophagy-related protein 5 / Autophagy protein Atg5, helix rich domain / Autophagy protein Atg5, UblA domain / Autophagy protein ATG5, UblB domain / Beta-propeller repeat TECPR / Beta propeller repeats in Physarum polycephalum tectonins, Limulus lectin L-6 and animal hypothetical proteins. / Serum Albumin; Chain A, Domain 1 / Phosphatidylinositol 3-kinase Catalytic Subunit; Chain A, domain 1 / Ubiquitin-like (UB roll) / PH-like domain superfamily / Roll / Orthogonal Bundle / Mainly Alpha / Alpha Beta類似検索 - ドメイン・相同性 Tectonin beta-propeller repeat-containing protein 1 / Autophagy protein 5類似検索 - 構成要素 |
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生物種 | Homo sapiens (ヒト) |
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手法 | X線回折 / シンクロトロン / 解像度: 1.802 Å |
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データ登録者 | Kim, J.H. / Hong, S.B. / Song, H.K. |
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引用 | ジャーナル: Autophagy / 年: 2015 タイトル: Insights into autophagosome maturation revealed by the structures of ATG5 with its interacting partners 著者: Kim, J.H. / Hong, S.B. / Lee, J.K. / Han, S. / Roh, K.H. / Lee, K.E. / Kim, Y.K. / Choi, E.J. / Song, H.K. |
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履歴 | 登録 | 2014年6月10日 | 登録サイト: RCSB / 処理サイト: PDBJ |
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改定 1.0 | 2015年3月11日 | Provider: repository / タイプ: Initial release |
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改定 1.1 | 2020年1月29日 | Group: Data collection / Derived calculations / Source and taxonomy カテゴリ: diffrn_source / entity_src_gen ...diffrn_source / entity_src_gen / pdbx_struct_assembly / pdbx_struct_assembly_gen / pdbx_struct_assembly_prop / pdbx_struct_oper_list Item: _diffrn_source.pdbx_synchrotron_site / _entity_src_gen.pdbx_alt_source_flag ..._diffrn_source.pdbx_synchrotron_site / _entity_src_gen.pdbx_alt_source_flag / _pdbx_struct_assembly.oligomeric_details / _pdbx_struct_assembly_gen.asym_id_list / _pdbx_struct_assembly_prop.type / _pdbx_struct_assembly_prop.value / _pdbx_struct_oper_list.symmetry_operation |
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改定 1.2 | 2024年3月20日 | Group: Data collection / Database references / カテゴリ: chem_comp_atom / chem_comp_bond / database_2 Item: _database_2.pdbx_DOI / _database_2.pdbx_database_accession |
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