Entry | Database: PDB / ID: 4rwt |
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Title | Structure of actin-Lmod complex |
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Components | |
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Keywords | STRUCTURAL PROTEIN / leucine rich region / actin nucleation / actin |
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Function / homology | Function and homology information
Gap junction degradation / Formation of annular gap junctions / EPHB-mediated forward signaling / EPH-ephrin mediated repulsion of cells / VEGFA-VEGFR2 Pathway / Cell-extracellular matrix interactions / RHOBTB2 GTPase cycle / RHOF GTPase cycle / pointed-end actin filament capping / MAP2K and MAPK activation ...Gap junction degradation / Formation of annular gap junctions / EPHB-mediated forward signaling / EPH-ephrin mediated repulsion of cells / VEGFA-VEGFR2 Pathway / Cell-extracellular matrix interactions / RHOBTB2 GTPase cycle / RHOF GTPase cycle / pointed-end actin filament capping / MAP2K and MAPK activation / Platelet degranulation / RHO GTPases Activate WASPs and WAVEs / Regulation of actin dynamics for phagocytic cup formation / DNA Damage Recognition in GG-NER / Clathrin-mediated endocytosis / myofibril assembly / UCH proteinases / sperm individualization / actin nucleation / maintenance of protein location in cell / brahma complex / Ino80 complex / tube formation / M band / sarcomere organization / myofibril / positive regulation of actin filament polymerization / tropomyosin binding / striated muscle thin filament / mitotic cytokinesis / actin monomer binding / muscle contraction / actin filament polymerization / sarcomere / actin filament organization / actin filament / Hydrolases; Acting on acid anhydrides; Acting on acid anhydrides to facilitate cellular and subcellular movement / actin binding / chromatin remodeling / cytoskeleton / hydrolase activity / ATP binding / cytoplasmSimilarity search - Function Tropomodulin / Tropomodulin / WH2 domain / WH2 domain profile. / Leucine-rich repeat, LRR (right-handed beta-alpha superhelix) / Ribonuclease Inhibitor / ATPase, substrate binding domain, subdomain 4 / Actin; Chain A, domain 4 / Alpha-Beta Horseshoe / ATPase, nucleotide binding domain ...Tropomodulin / Tropomodulin / WH2 domain / WH2 domain profile. / Leucine-rich repeat, LRR (right-handed beta-alpha superhelix) / Ribonuclease Inhibitor / ATPase, substrate binding domain, subdomain 4 / Actin; Chain A, domain 4 / Alpha-Beta Horseshoe / ATPase, nucleotide binding domain / Actins signature 1. / Actin, conserved site / Actins signature 2. / Actin/actin-like conserved site / Actins and actin-related proteins signature. / Actin / Actin family / Actin / Leucine-rich repeat domain superfamily / ATPase, nucleotide binding domain / Nucleotidyltransferase; domain 5 / Alpha-Beta Complex / 2-Layer Sandwich / Alpha BetaSimilarity search - Domain/homology |
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Biological species | Drosophila melanogaster (fruit fly) Homo sapiens (human) |
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Method | X-RAY DIFFRACTION / SYNCHROTRON / MOLECULAR REPLACEMENT / Resolution: 2.98 Å |
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Authors | Chen, X. / Ni, F. / Wang, Q. |
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Citation | Journal: Proc.Natl.Acad.Sci.USA / Year: 2015 Title: Mechanisms of leiomodin 2-mediated regulation of actin filament in muscle cells. Authors: Chen, X. / Ni, F. / Kondrashkina, E. / Ma, J. / Wang, Q. |
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History | Deposition | Dec 5, 2014 | Deposition site: RCSB / Processing site: RCSB |
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Revision 1.0 | Oct 14, 2015 | Provider: repository / Type: Initial release |
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Revision 1.1 | Oct 28, 2015 | Group: Database references |
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Revision 1.2 | Feb 28, 2024 | Group: Data collection / Database references / Derived calculations Category: chem_comp_atom / chem_comp_bond ...chem_comp_atom / chem_comp_bond / database_2 / pdbx_struct_conn_angle / struct_conn / struct_ref_seq_dif / struct_site Item: _database_2.pdbx_DOI / _database_2.pdbx_database_accession ..._database_2.pdbx_DOI / _database_2.pdbx_database_accession / _pdbx_struct_conn_angle.ptnr1_auth_asym_id / _pdbx_struct_conn_angle.ptnr1_auth_comp_id / _pdbx_struct_conn_angle.ptnr1_auth_seq_id / _pdbx_struct_conn_angle.ptnr1_label_asym_id / _pdbx_struct_conn_angle.ptnr1_label_atom_id / _pdbx_struct_conn_angle.ptnr1_label_comp_id / _pdbx_struct_conn_angle.ptnr1_label_seq_id / _pdbx_struct_conn_angle.ptnr2_auth_asym_id / _pdbx_struct_conn_angle.ptnr2_label_asym_id / _pdbx_struct_conn_angle.ptnr3_auth_asym_id / _pdbx_struct_conn_angle.ptnr3_auth_comp_id / _pdbx_struct_conn_angle.ptnr3_auth_seq_id / _pdbx_struct_conn_angle.ptnr3_label_asym_id / _pdbx_struct_conn_angle.ptnr3_label_atom_id / _pdbx_struct_conn_angle.ptnr3_label_comp_id / _pdbx_struct_conn_angle.ptnr3_label_seq_id / _pdbx_struct_conn_angle.value / _struct_conn.pdbx_dist_value / _struct_conn.ptnr1_auth_asym_id / _struct_conn.ptnr1_auth_comp_id / _struct_conn.ptnr1_auth_seq_id / _struct_conn.ptnr1_label_asym_id / _struct_conn.ptnr1_label_atom_id / _struct_conn.ptnr1_label_comp_id / _struct_conn.ptnr1_label_seq_id / _struct_conn.ptnr2_auth_asym_id / _struct_conn.ptnr2_label_asym_id / _struct_ref_seq_dif.details / _struct_site.pdbx_auth_asym_id / _struct_site.pdbx_auth_comp_id / _struct_site.pdbx_auth_seq_id |
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