登録情報 | データベース: PDB / ID: 4o8h |
---|
タイトル | 0.85A resolution structure of PEG 400 Bound Cyclophilin D |
---|
要素 | Peptidyl-prolyl cis-trans isomerase F, mitochondrial |
---|
キーワード | ISOMERASE |
---|
機能・相同性 | 機能・相同性情報
regulation of proton-transporting ATPase activity, rotational mechanism / negative regulation of oxidative phosphorylation uncoupler activity / mitochondrial outer membrane permeabilization involved in programmed cell death / regulation of mitochondrial membrane permeability involved in programmed necrotic cell death / skeletal muscle fiber differentiation / mitochondrial permeability transition pore complex / mitochondrial depolarization / cellular response to arsenic-containing substance / negative regulation of ATP-dependent activity / negative regulation of oxidative phosphorylation ...regulation of proton-transporting ATPase activity, rotational mechanism / negative regulation of oxidative phosphorylation uncoupler activity / mitochondrial outer membrane permeabilization involved in programmed cell death / regulation of mitochondrial membrane permeability involved in programmed necrotic cell death / skeletal muscle fiber differentiation / mitochondrial permeability transition pore complex / mitochondrial depolarization / cellular response to arsenic-containing substance / negative regulation of ATP-dependent activity / negative regulation of oxidative phosphorylation / regulation of mitochondrial membrane permeability / cyclosporin A binding / negative regulation of release of cytochrome c from mitochondria / necroptotic process / apoptotic mitochondrial changes / protein peptidyl-prolyl isomerization / negative regulation of intrinsic apoptotic signaling pathway / cellular response to calcium ion / peptide binding / peptidylprolyl isomerase / peptidyl-prolyl cis-trans isomerase activity / response to ischemia / cellular response to hydrogen peroxide / protein folding / mitochondrial inner membrane / mitochondrial matrix / negative regulation of apoptotic process / mitochondrion / membrane / cytoplasm類似検索 - 分子機能 Cyclophilin-like / Cyclophilin / Cyclophilin-type peptidyl-prolyl cis-trans isomerase, conserved site / Cyclophilin-type peptidyl-prolyl cis-trans isomerase signature. / Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain profile. / Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain / Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD / Cyclophilin-like domain superfamily / Beta Barrel / Mainly Beta類似検索 - ドメイン・相同性 DI(HYDROXYETHYL)ETHER / Peptidyl-prolyl cis-trans isomerase F, mitochondrial類似検索 - 構成要素 |
---|
生物種 | Homo sapiens (ヒト) |
---|
手法 | X線回折 / シンクロトロン / 分子置換 / 解像度: 0.85 Å |
---|
データ登録者 | Lovell, S. / Valasani, K.R. / Battaile, K.P. / Wang, C. / Yan, S.S. |
---|
引用 | ジャーナル: Acta Crystallogr F Struct Biol Commun / 年: 2014 タイトル: High-resolution crystal structures of two crystal forms of human cyclophilin D in complex with PEG 400 molecules. 著者: Valasani, K.R. / Carlson, E.A. / Battaile, K.P. / Bisson, A. / Wang, C. / Lovell, S. / ShiDu Yan, S. |
---|
履歴 | 登録 | 2013年12月27日 | 登録サイト: RCSB / 処理サイト: RCSB |
---|
改定 1.0 | 2014年6月11日 | Provider: repository / タイプ: Initial release |
---|
改定 1.1 | 2014年9月24日 | Group: Database references |
---|
改定 1.2 | 2017年11月22日 | Group: Refinement description / カテゴリ: software / Item: _software.name |
---|
改定 1.3 | 2023年9月20日 | Group: Data collection / Database references ...Data collection / Database references / Derived calculations / Refinement description カテゴリ: chem_comp_atom / chem_comp_bond ...chem_comp_atom / chem_comp_bond / database_2 / pdbx_initial_refinement_model / struct_ref_seq_dif / struct_site Item: _database_2.pdbx_DOI / _database_2.pdbx_database_accession ..._database_2.pdbx_DOI / _database_2.pdbx_database_accession / _struct_ref_seq_dif.details / _struct_site.pdbx_auth_asym_id / _struct_site.pdbx_auth_comp_id / _struct_site.pdbx_auth_seq_id |
---|
|
---|