登録情報 | データベース: PDB / ID: 4hsc |
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タイトル | Crystal structure of a cholesterol dependent cytolysin |
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要素 | Streptolysin O |
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キーワード | TOXIN / cholesterol-dependent cytolysins / membrane insertion / membrane pore / pore-forming toxins / pore-forming toxin |
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機能・相同性 | 機能・相同性情報
hemolysis in another organism / cholesterol binding / : / toxin activity / membrane => GO:0016020 / host cell plasma membrane / extracellular region類似検索 - 分子機能 Carboxypeptidase Inhibitor; Chain A - #20 / Perfringolysin / HIV-1 Reverse Transcriptase; Chain A, domain 3 / Thiol-activated cytolysin superfamily/Thiol-activated cytolysin, alpha-beta domain / Perfringolysin, domain 4 / Carboxypeptidase Inhibitor; Chain A / Thiol-activated cytolysins signature. / Thiol-activated cytolysin C-terminal / Thiol-activated cytolysin, C-terminal domain superfamily / Thiol-activated cytolysin beta sandwich domain ...Carboxypeptidase Inhibitor; Chain A - #20 / Perfringolysin / HIV-1 Reverse Transcriptase; Chain A, domain 3 / Thiol-activated cytolysin superfamily/Thiol-activated cytolysin, alpha-beta domain / Perfringolysin, domain 4 / Carboxypeptidase Inhibitor; Chain A / Thiol-activated cytolysins signature. / Thiol-activated cytolysin C-terminal / Thiol-activated cytolysin, C-terminal domain superfamily / Thiol-activated cytolysin beta sandwich domain / Thiol-activated cytolysin / Thiol-activated cytolysin superfamily / Thiol-activated cytolysin, alpha-beta domain superfamily / Thiol-activated cytolysin / Glutaredoxin / Alpha-Beta Complex / Immunoglobulin-like / Sandwich / 2-Layer Sandwich / 3-Layer(aba) Sandwich / Mainly Beta / Alpha Beta類似検索 - ドメイン・相同性 |
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生物種 | Streptococcus pyogenes (化膿レンサ球菌) |
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手法 | X線回折 / 分子置換 / 解像度: 2.1 Å |
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データ登録者 | Feil, S.C. / Parker, M.W. |
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引用 | ジャーナル: J.Mol.Biol. / 年: 2014 タイトル: Structural studies of Streptococcus pyogenes streptolysin O provide insights into the early steps of membrane penetration. 著者: Feil, S.C. / Ascher, D.B. / Kuiper, M.J. / Tweten, R.K. / Parker, M.W. |
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履歴 | 登録 | 2012年10月29日 | 登録サイト: RCSB / 処理サイト: RCSB |
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改定 1.0 | 2013年10月30日 | Provider: repository / タイプ: Initial release |
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改定 1.1 | 2019年10月30日 | Group: Data collection / Database references / Derived calculations カテゴリ: citation / citation_author ...citation / citation_author / pdbx_struct_sheet_hbond / struct_sheet / struct_sheet_order / struct_sheet_range Item: _citation.country / _citation.journal_abbrev ..._citation.country / _citation.journal_abbrev / _citation.journal_id_ASTM / _citation.journal_id_CSD / _citation.journal_id_ISSN / _citation.journal_volume / _citation.page_first / _citation.page_last / _citation.pdbx_database_id_DOI / _citation.pdbx_database_id_PubMed / _citation.title / _citation.year / _citation_author.name |
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改定 1.2 | 2023年9月20日 | Group: Data collection / Database references / Refinement description カテゴリ: chem_comp_atom / chem_comp_bond ...chem_comp_atom / chem_comp_bond / database_2 / pdbx_initial_refinement_model Item: _database_2.pdbx_DOI / _database_2.pdbx_database_accession |
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