Entry Database : PDB / ID : 4d07 Structure visualization Downloads & linksTitle DYNLL2 dynein light chain binds to an extended, unstructured linear motif of myosin 5a tail ComponentsDYNEIN LIGHT CHAIN 2, CYTOPLASMIC MYOSIN VA VARIANT DetailsKeywords MOTOR PROTEIN / INSTRINSICALLY DISORDERED DOMAIN / HUB PROTEINFunction / homology Function and homology informationFunction Domain/homology Component
myosin V complex / Activation of BMF and translocation to mitochondria / 9+0 non-motile cilium / post-Golgi vesicle-mediated transport / insulin-responsive compartment / melanosome transport / actin filament-based movement / ciliary tip / filopodium tip / Intraflagellar transport ... myosin V complex / Activation of BMF and translocation to mitochondria / 9+0 non-motile cilium / post-Golgi vesicle-mediated transport / insulin-responsive compartment / melanosome transport / actin filament-based movement / ciliary tip / filopodium tip / Intraflagellar transport / COPI-independent Golgi-to-ER retrograde traffic / cytoplasmic dynein complex / vesicle transport along actin filament / myosin complex / microfilament motor activity / Macroautophagy / dynein intermediate chain binding / Insulin processing / cytoskeletal motor activity / Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal / microtubule-based process / COPI-mediated anterograde transport / Mitotic Prometaphase / EML4 and NUDC in mitotic spindle formation / vesicle-mediated transport / ruffle / Resolution of Sister Chromatid Cohesion / HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand / MHC class II antigen presentation / actin filament organization / RHO GTPases Activate Formins / Translocation of SLC2A4 (GLUT4) to the plasma membrane / protein localization to plasma membrane / FCGR3A-mediated phagocytosis / cilium / Regulation of actin dynamics for phagocytic cup formation / small GTPase binding / Aggrephagy / HCMV Early Events / cellular response to insulin stimulus / Separation of Sister Chromatids / melanosome / actin filament binding / actin cytoskeleton / protein transport / actin binding / growth cone / postsynapse / microtubule / cytoskeleton / calmodulin binding / neuron projection / centrosome / glutamatergic synapse / RNA binding / extracellular exosome / ATP binding / membrane / nucleus / plasma membrane / cytosol / cytoplasm Similarity search - Function Protein Inhibitor Of Neuronal Nitric Oxide Synthase / Protein Inhibitor Of Neuronal Nitric Oxide Synthase; / Dynein light chain, type 1/2, conserved site / Dynein light chain type 1 signature. / Myosin 5a, cargo-binding domain / Dynein light chain type 1 / Dynein light chain, type 1/2 / Dynein light chain superfamily / Dynein light chain type 1 / Class V myosin, motor domain ... Protein Inhibitor Of Neuronal Nitric Oxide Synthase / Protein Inhibitor Of Neuronal Nitric Oxide Synthase; / Dynein light chain, type 1/2, conserved site / Dynein light chain type 1 signature. / Myosin 5a, cargo-binding domain / Dynein light chain type 1 / Dynein light chain, type 1/2 / Dynein light chain superfamily / Dynein light chain type 1 / Class V myosin, motor domain / Dilute domain / DIL domain / Dilute domain profile. / DIL / IQ calmodulin-binding motif / Myosin, N-terminal, SH3-like / Myosin N-terminal SH3-like domain profile. / Short calmodulin-binding motif containing conserved Ile and Gln residues. / Myosin head, motor domain / Myosin head (motor domain) / Myosin motor domain profile. / Myosin. Large ATPases. / IQ motif profile. / IQ motif, EF-hand binding site / Kinesin motor domain superfamily / P-loop containing nucleoside triphosphate hydrolase / 2-Layer Sandwich / Alpha Beta Similarity search - Domain/homologyBiological species HOMO SAPIENS (human)Method X-RAY DIFFRACTION / SYNCHROTRON / MOLECULAR REPLACEMENT / Resolution : 1.85 Å DetailsAuthors Bodor, A. / Radnai, L. / Hetenyi, C. / Rapali, P. / Lang, A. / Kover, K.E. / Perczel, A. / Wahlgren, W.Y. / Katona, G. / Nyitray, L. CitationJournal : Biochemistry / Year : 2014Title : Dynll2 Dynein Light Chain Binds to an Extended Linear Motif of Myosin 5A Tail that Has Structural Plasticity.Authors : Bodor, A. / Radnai, L. / Hetenyi, C. / Rapali, P. / Lang, A. / Kover, K.E. / Perczel, A. / Wahlgren, W.Y. / Katona, G. / Nyitray, L. History Deposition Apr 24, 2014 Deposition site : PDBE / Processing site : PDBERevision 1.0 Oct 22, 2014 Provider : repository / Type : Initial releaseRevision 1.1 Oct 29, 2014 Group : Database referencesRevision 1.2 Dec 3, 2014 Group : Database referencesRevision 1.3 Dec 20, 2023 Group : Data collection / Database references ... Data collection / Database references / Derived calculations / Other / Refinement description Category : chem_comp_atom / chem_comp_bond ... chem_comp_atom / chem_comp_bond / database_2 / pdbx_database_status / pdbx_initial_refinement_model / pdbx_struct_conn_angle / struct_conn / struct_site Item : _database_2.pdbx_DOI / _database_2.pdbx_database_accession ... _database_2.pdbx_DOI / _database_2.pdbx_database_accession / _pdbx_database_status.status_code_sf / _pdbx_struct_conn_angle.ptnr1_auth_comp_id / _pdbx_struct_conn_angle.ptnr1_auth_seq_id / _pdbx_struct_conn_angle.ptnr1_label_atom_id / _pdbx_struct_conn_angle.ptnr1_label_comp_id / _pdbx_struct_conn_angle.ptnr1_label_seq_id / _pdbx_struct_conn_angle.ptnr3_auth_comp_id / _pdbx_struct_conn_angle.ptnr3_auth_seq_id / _pdbx_struct_conn_angle.ptnr3_label_atom_id / _pdbx_struct_conn_angle.ptnr3_label_comp_id / _pdbx_struct_conn_angle.ptnr3_label_seq_id / _pdbx_struct_conn_angle.value / _struct_conn.pdbx_dist_value / _struct_conn.ptnr1_auth_comp_id / _struct_conn.ptnr1_auth_seq_id / _struct_conn.ptnr1_label_asym_id / _struct_conn.ptnr1_label_atom_id / _struct_conn.ptnr1_label_comp_id / _struct_conn.ptnr1_label_seq_id / _struct_conn.ptnr2_auth_comp_id / _struct_conn.ptnr2_auth_seq_id / _struct_conn.ptnr2_label_asym_id / _struct_conn.ptnr2_label_atom_id / _struct_conn.ptnr2_label_comp_id / _struct_conn.ptnr2_label_seq_id / _struct_site.pdbx_auth_asym_id / _struct_site.pdbx_auth_comp_id / _struct_site.pdbx_auth_seq_id
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