登録情報 データベース : PDB / ID : 4ccz 構造の表示 ダウンロードとリンクタイトル Crystal structure of human 5-methyltetrahydrofolate-homocysteine methyltransferase, the homocysteine and folate binding domains 要素METHIONINE SYNTHASE 詳細 キーワード TRANSFERASE機能・相同性 機能・相同性情報分子機能 ドメイン・相同性 構成要素
Defective MTRR causes HMAE / Defective MTR causes HMAG / Sulfur amino acid metabolism / cobalamin metabolic process / Cobalamin (Cbl) metabolism / methionine synthase / methionine synthase activity / homocysteine metabolic process / Methylation / methionine biosynthetic process ... Defective MTRR causes HMAE / Defective MTR causes HMAG / Sulfur amino acid metabolism / cobalamin metabolic process / Cobalamin (Cbl) metabolism / methionine synthase / methionine synthase activity / homocysteine metabolic process / Methylation / methionine biosynthetic process / cobalamin binding / tetrahydrofolate metabolic process / axon regeneration / RHOH GTPase cycle / cellular response to nitric oxide / response to axon injury / nervous system development / methylation / zinc ion binding / cytosol 類似検索 - 分子機能 Homocysteine-binding-like domain / Vitamin B12-dependent methionine synthase, activation domain / Vitamin B12 dependent methionine synthase, activation domain / AdoMet activation domain profile. / Cobalamin-dependent methionine synthase / Methionine synthase, B12-binding domain / Vitamin B12-dependent methionine synthase, activation domain superfamily / B12-binding N-terminal domain profile. / B12 binding domain / Homocysteine-binding domain ... Homocysteine-binding-like domain / Vitamin B12-dependent methionine synthase, activation domain / Vitamin B12 dependent methionine synthase, activation domain / AdoMet activation domain profile. / Cobalamin-dependent methionine synthase / Methionine synthase, B12-binding domain / Vitamin B12-dependent methionine synthase, activation domain superfamily / B12-binding N-terminal domain profile. / B12 binding domain / Homocysteine-binding domain / Homocysteine-binding domain superfamily / : / Homocysteine S-methyltransferase / Homocysteine-binding domain profile. / Cobalamin (vitamin B12)-binding module, cap domain / B12 binding domain / Methionine synthase domain / B12 binding domain / Cobalamin-binding domain superfamily / B12-binding domain profile. / Cobalamin (vitamin B12)-binding domain / Dihydropteroate synthase-like / Pterin-binding domain / Pterin binding enzyme / Pterin-binding domain profile. / Dihydropteroate synthase-like / TIM Barrel / Alpha-Beta Barrel / Alpha Beta 類似検索 - ドメイン・相同性 (6S)-5,6,7,8-TETRAHYDROFOLATE / Methionine synthase 類似検索 - 構成要素生物種 HOMO SAPIENS (ヒト)手法 X線回折 / シンクロトロン / 分子置換 / 解像度 : 2.7 Å 詳細データ登録者 Vollmar, M. / Kiyani, W. / Krojer, T. / Goubin, S. / Burgess-Brown, N. / von Delft, F. / Oppermann, U. / Edwards, A. / Arrowsmith, C. / Bountra, C. / Yue, W.W. 引用ジャーナル : To be Published タイトル : Crystal Structure of Human 5-Methyltetrahydrofolate-Homocysteine Methyltransferase, the Homocysteine and Folate Binding Domains著者 : Vollmar, M. / Kiyani, W. / Krojer, T. / Goubin, S. / Burgess-Brown, N. / von Delft, F. / Oppermann, U. / Edwards, A. / Arrowsmith, C. / Bountra, C. / Yue, W.W. 履歴 登録 2013年10月29日 登録サイト : PDBE / 処理サイト : PDBE改定 1.0 2013年11月27日 Provider : repository / タイプ : Initial release改定 1.1 2018年1月24日 Group : Database references / カテゴリ : citation_author / Item : _citation_author.name改定 1.2 2023年12月20日 Group : Data collection / Database references ... Data collection / Database references / Derived calculations / Other / Refinement description カテゴリ : chem_comp_atom / chem_comp_bond ... chem_comp_atom / chem_comp_bond / database_2 / pdbx_database_status / pdbx_initial_refinement_model / struct_site Item : _database_2.pdbx_DOI / _database_2.pdbx_database_accession ... _database_2.pdbx_DOI / _database_2.pdbx_database_accession / _pdbx_database_status.status_code_sf / _struct_site.pdbx_auth_asym_id / _struct_site.pdbx_auth_comp_id / _struct_site.pdbx_auth_seq_id
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