登録情報 | データベース: PDB / ID: 4ajv |
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タイトル | Structure of mouse ZP-C domain of TGF-Beta-Receptor-3 |
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要素 | TRANSFORMING GROWTH FACTOR BETA RECEPTOR TYPE 3 |
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キーワード | SIGNALING PROTEIN |
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機能・相同性 | 機能・相同性情報
epicardial cell to mesenchymal cell transition / negative regulation of apoptotic process involved in morphogenesis / : / response to luteinizing hormone / epicardium-derived cardiac fibroblast cell development / transforming growth factor beta receptor activity, type III / transforming growth factor beta receptor complex assembly / : / inhibin-betaglycan-ActRII complex / muscular septum morphogenesis ...epicardial cell to mesenchymal cell transition / negative regulation of apoptotic process involved in morphogenesis / : / response to luteinizing hormone / epicardium-derived cardiac fibroblast cell development / transforming growth factor beta receptor activity, type III / transforming growth factor beta receptor complex assembly / : / inhibin-betaglycan-ActRII complex / muscular septum morphogenesis / definitive erythrocyte differentiation / response to follicle-stimulating hormone / coronary vasculature morphogenesis / visceral serous pericardium development / response to prostaglandin E / vasculogenesis involved in coronary vascular morphogenesis / transforming growth factor beta receptor activity / secondary palate development / ventricular compact myocardium morphogenesis / regulation of transforming growth factor beta receptor signaling pathway / negative regulation of epithelial cell migration / regulation of protein binding / collagen metabolic process / cardiac epithelial to mesenchymal transition / transforming growth factor beta receptor binding / type II transforming growth factor beta receptor binding / activin binding / heart trabecula morphogenesis / coronary vasculature development / heart trabecula formation / positive regulation of BMP signaling pathway / glycosaminoglycan binding / transforming growth factor beta binding / negative regulation of epithelial to mesenchymal transition / definitive hemopoiesis / cardiac muscle cell proliferation / ventricular cardiac muscle tissue morphogenesis / ventricular septum morphogenesis / roof of mouth development / BMP signaling pathway / blood vessel development / fibroblast growth factor binding / positive regulation of transforming growth factor beta receptor signaling pathway / outflow tract morphogenesis / plasma membrane => GO:0005886 / SMAD binding / blastocyst development / epithelial to mesenchymal transition / blood vessel remodeling / vasculogenesis / coreceptor activity / positive regulation of cardiac muscle cell proliferation / blood vessel diameter maintenance / extracellular matrix / transforming growth factor beta receptor signaling pathway / negative regulation of transforming growth factor beta receptor signaling pathway / liver development / PDZ domain binding / osteoblast differentiation / negative regulation of epithelial cell proliferation / cell migration / positive regulation of NF-kappaB transcription factor activity / heparin binding / protein-containing complex assembly / angiogenesis / in utero embryonic development / receptor complex / membrane => GO:0016020 / intracellular signal transduction / immune response / external side of plasma membrane / negative regulation of gene expression / positive regulation of cell population proliferation / cell surface / endoplasmic reticulum / extracellular space / cytoplasm類似検索 - 分子機能 Zona pellucida, ZP-C domain / Zona pellucida domain, conserved site / ZP domain signature. / Zona pellucida-like domain / Zona pellucida (ZP) domain / ZP domain profile. / Zona pellucida domain / Immunoglobulin-like / Sandwich / Mainly Beta類似検索 - ドメイン・相同性 Transforming growth factor beta receptor type 3類似検索 - 構成要素 |
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生物種 | MUS MUSCULUS (ハツカネズミ) |
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手法 | X線回折 / シンクロトロン / 分子置換 / 解像度: 2.7 Å |
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データ登録者 | Diestel, U. / Resch, M. / Meinhardt, K. / Weiler, S. / Hellmann, T.V. / Nickel, J. / Eichler, J. / Muller, Y.A. |
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引用 | ジャーナル: Plos One / 年: 2013 タイトル: Identification of a Novel Tgf-Beta-Binding Site in the Zona Pellucida C-Terminal (Zp-C) Domain of Tgf-Beta-Receptor-3 (Tgfr-3). 著者: Diestel, U. / Resch, M. / Meinhardt, K. / Weiler, S. / Hellmann, T.V. / Mueller, T.D. / Nickel, J. / Eichler, J. / Muller, Y.A. |
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履歴 | 登録 | 2012年2月20日 | 登録サイト: PDBE / 処理サイト: PDBE |
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改定 1.0 | 2013年2月27日 | Provider: repository / タイプ: Initial release |
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改定 1.1 | 2013年7月17日 | Group: Database references |
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改定 1.2 | 2023年12月20日 | Group: Data collection / Database references ...Data collection / Database references / Other / Refinement description カテゴリ: chem_comp_atom / chem_comp_bond ...chem_comp_atom / chem_comp_bond / database_2 / pdbx_database_status / pdbx_initial_refinement_model Item: _database_2.pdbx_DOI / _database_2.pdbx_database_accession / _pdbx_database_status.status_code_sf |
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