登録情報 | データベース: PDB / ID: 3dwb |
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タイトル | structure of human ECE-1 complexed with phosphoramidon |
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要素 | Endothelin-converting enzyme 1 |
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キーワード | HYDROLASE / protein / Disease mutation / Glycoprotein / Hirschsprung disease / Membrane / Metal-binding / Metalloprotease / Phosphoprotein / Protease / Signal-anchor / Transmembrane / MCH_ECE_H_25A1_LT1.PDB |
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機能・相同性 | 機能・相同性情報
endothelin-converting enzyme 1 / calcitonin catabolic process / : / endothelin maturation / Weibel-Palade body / substance P catabolic process / ear development / hormone catabolic process / bradykinin catabolic process / pharyngeal system development ...endothelin-converting enzyme 1 / calcitonin catabolic process / : / endothelin maturation / Weibel-Palade body / substance P catabolic process / ear development / hormone catabolic process / bradykinin catabolic process / pharyngeal system development / regulation of systemic arterial blood pressure by endothelin / peptide hormone processing / embryonic digit morphogenesis / positive regulation of receptor recycling / peptide hormone binding / regulation of vasoconstriction / Peptide ligand-binding receptors / protein processing / metalloendopeptidase activity / heart development / endopeptidase activity / vesicle / membrane => GO:0016020 / early endosome / endosome / lysosomal membrane / external side of plasma membrane / perinuclear region of cytoplasm / protein homodimerization activity / zinc ion binding / extracellular exosome / membrane / plasma membrane類似検索 - 分子機能 Endothelin-converting enzyme 1 / Neutral endopeptidase; domain 2 / Neutral endopeptidase , domain2 / Neprilysin-like (M13) protease domain profile. / Peptidase M13 / Peptidase M13, N-terminal domain / Peptidase M13, C-terminal domain / Peptidase M13, domain 2 / Peptidase family M13 / Peptidase family M13 ...Endothelin-converting enzyme 1 / Neutral endopeptidase; domain 2 / Neutral endopeptidase , domain2 / Neprilysin-like (M13) protease domain profile. / Peptidase M13 / Peptidase M13, N-terminal domain / Peptidase M13, C-terminal domain / Peptidase M13, domain 2 / Peptidase family M13 / Peptidase family M13 / Collagenase (Catalytic Domain) / Collagenase (Catalytic Domain) / Metallopeptidase, catalytic domain superfamily / Neutral zinc metallopeptidases, zinc-binding region signature. / Orthogonal Bundle / 3-Layer(aba) Sandwich / Mainly Alpha / Alpha Beta類似検索 - ドメイン・相同性 PHOSPHORAMIDON / 5-(2-hydroxyethyl)nonane-1,9-diol / Chem-RDF / Endothelin-converting enzyme 1類似検索 - 構成要素 |
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生物種 | Homo sapiens (ヒト) |
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手法 | X線回折 / 分子置換 / 解像度: 2.38 Å |
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データ登録者 | Oefner, C. |
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引用 | ジャーナル: J.Mol.Biol. / 年: 2009 タイトル: Structure of human endothelin-converting enzyme I complexed with phosphoramidon 著者: Schulz, H. / Dale, G.E. / Karimi-Nejad, Y. / Oefner, C. |
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履歴 | 登録 | 2008年7月22日 | 登録サイト: RCSB / 処理サイト: PDBJ |
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改定 1.0 | 2008年11月25日 | Provider: repository / タイプ: Initial release |
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改定 1.1 | 2011年7月13日 | Group: Advisory / Version format compliance |
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改定 1.2 | 2012年12月12日 | Group: Other |
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改定 1.3 | 2021年11月10日 | Group: Database references / Derived calculations / カテゴリ: database_2 / struct_ref_seq_dif / struct_site Item: _database_2.pdbx_DOI / _database_2.pdbx_database_accession ..._database_2.pdbx_DOI / _database_2.pdbx_database_accession / _struct_ref_seq_dif.details / _struct_site.pdbx_auth_asym_id / _struct_site.pdbx_auth_comp_id / _struct_site.pdbx_auth_seq_id |
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改定 1.4 | 2023年11月1日 | Group: Data collection / Refinement description カテゴリ: chem_comp_atom / chem_comp_bond / pdbx_initial_refinement_model |
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改定 1.5 | 2024年3月20日 | Group: Source and taxonomy / カテゴリ: pdbx_entity_src_syn |
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