登録情報 | データベース: PDB / ID: 3dbq |
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タイトル | Crystal structure of TTK kinase domain |
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要素 | Dual specificity protein kinase TTK |
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キーワード | TRANSFERASE / Mps1 structure / Kinase activation / Phosphorylation / ATP-binding / Kinase / Nucleotide-binding / Phosphoprotein / Polymorphism / Serine/threonine-protein kinase / Tyrosine-protein kinase |
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機能・相同性 | 機能・相同性情報
protein localization to meiotic spindle midzone / meiotic spindle assembly checkpoint signaling / kinetochore binding / female meiosis chromosome segregation / protein localization to kinetochore / dual-specificity kinase / spindle organization / mitotic spindle assembly checkpoint signaling / protein serine/threonine/tyrosine kinase activity / mitotic spindle organization ...protein localization to meiotic spindle midzone / meiotic spindle assembly checkpoint signaling / kinetochore binding / female meiosis chromosome segregation / protein localization to kinetochore / dual-specificity kinase / spindle organization / mitotic spindle assembly checkpoint signaling / protein serine/threonine/tyrosine kinase activity / mitotic spindle organization / chromosome segregation / kinetochore / spindle / protein tyrosine kinase activity / protein serine kinase activity / protein serine/threonine kinase activity / positive regulation of cell population proliferation / ATP binding / identical protein binding / membrane / nucleus / cytoplasm類似検索 - 分子機能 Protein kinase Mps1 family / Tetratricopeptide-like helical domain superfamily / Transferase(Phosphotransferase) domain 1 / Transferase(Phosphotransferase); domain 1 / Phosphorylase Kinase; domain 1 / Phosphorylase Kinase; domain 1 / Serine/threonine-protein kinase, active site / Serine/Threonine protein kinases active-site signature. / Protein kinase domain / Serine/Threonine protein kinases, catalytic domain ...Protein kinase Mps1 family / Tetratricopeptide-like helical domain superfamily / Transferase(Phosphotransferase) domain 1 / Transferase(Phosphotransferase); domain 1 / Phosphorylase Kinase; domain 1 / Phosphorylase Kinase; domain 1 / Serine/threonine-protein kinase, active site / Serine/Threonine protein kinases active-site signature. / Protein kinase domain / Serine/Threonine protein kinases, catalytic domain / Protein kinase, ATP binding site / Protein kinases ATP-binding region signature. / Protein kinase domain profile. / Protein kinase domain / Protein kinase-like domain superfamily / 2-Layer Sandwich / Orthogonal Bundle / Mainly Alpha / Alpha Beta類似検索 - ドメイン・相同性 |
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生物種 | Homo sapiens (ヒト) |
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手法 | X線回折 / シンクロトロン / 多波長異常分散 / 解像度: 2.7 Å |
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データ登録者 | Wang, W. / Yang, Y.T. / Gao, Y.F. / Zhu, S.C. / Wang, F. / Old, W. / Xu, Q.B. / Resing, K. / Ahn, N. / Lei, M. / Liu, X.D. |
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引用 | ジャーナル: J.CELL.MOL.MED. / 年: 2008 タイトル: Structural and Mechanistic Insights into Mps1 Kinase Activation 著者: Wang, W. / Yang, Y.T. / Gao, Y.F. / Xu, Q.B. / Wang, F. / Zhu, S.C. / Old, W. / Resing, K. / Ahn, N. / Lei, M. / Liu, X.D. |
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履歴 | 登録 | 2008年6月2日 | 登録サイト: RCSB / 処理サイト: PDBJ |
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改定 1.0 | 2009年2月10日 | Provider: repository / タイプ: Initial release |
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改定 1.1 | 2011年7月13日 | Group: Version format compliance |
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