- PDB-2yrc: Solution structure of the zf-Sec23_Sec24 from human Sec23A -
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Basic information
Entry
Database: PDB / ID: 2yrc
Title
Solution structure of the zf-Sec23_Sec24 from human Sec23A
Components
Protein transport protein Sec23AProtein targeting
Keywords
PROTEIN TRANSPORT / zinc binding / COPII / coat protein complex-II / endoplasmic reticulum / Golgi / Structural Genomics / NPPSFA / National Project on Protein Structural and Functional Analyses / RIKEN Structural Genomics/Proteomics Initiative / RSGI
Function / homology
Function and homology information
COPII-coated vesicle cargo loading / COPII vesicle coat / Regulation of cholesterol biosynthesis by SREBP (SREBF) / Cargo concentration in the ER / COPII-mediated vesicle transport / endoplasmic reticulum exit site / MHC class II antigen presentation / GTPase activator activity / protein localization to plasma membrane / Antigen Presentation: Folding, assembly and peptide loading of class I MHC ...COPII-coated vesicle cargo loading / COPII vesicle coat / Regulation of cholesterol biosynthesis by SREBP (SREBF) / Cargo concentration in the ER / COPII-mediated vesicle transport / endoplasmic reticulum exit site / MHC class II antigen presentation / GTPase activator activity / protein localization to plasma membrane / Antigen Presentation: Folding, assembly and peptide loading of class I MHC / intracellular protein transport / ER to Golgi transport vesicle membrane / Golgi membrane / endoplasmic reticulum membrane / SARS-CoV-2 activates/modulates innate and adaptive immune responses / perinuclear region of cytoplasm / zinc ion binding / cytosol Similarity search - Function
Conformer selection criteria: structures with the least restraint violations, target function Conformers calculated total number: 100 / Conformers submitted total number: 20
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