- PDB-2xpi: Crystal structure of APC/C hetero-tetramer Cut9-Hcn1 -
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Database: PDB / ID: 2xpi
Title
Crystal structure of APC/C hetero-tetramer Cut9-Hcn1
Components
ANAPHASE-PROMOTING COMPLEX SUBUNIT CUT9
ANAPHASE-PROMOTING COMPLEX SUBUNIT HCN1 HCN1/CDC26,20S CYCLOSOME/APC COMPLEX PROTEIN HCN1, CHAPERONE-LIKE PROTEIN HCN1, HIGH COPY SUPPRESSOR OF CUT9 PROTEIN 1
: / Inactivation of APC/C via direct inhibition of the APC/C complex / : / : / Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase / : / Separation of Sister Chromatids / Regulation of APC/C activators between G1/S and early anaphase / : / pericentric heterochromatin => GO:0005721 ...: / Inactivation of APC/C via direct inhibition of the APC/C complex / : / : / Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase / : / Separation of Sister Chromatids / Regulation of APC/C activators between G1/S and early anaphase / : / pericentric heterochromatin => GO:0005721 / positive regulation of exit from mitosis / Antigen processing: Ubiquitination & Proteasome degradation / anaphase-promoting complex / metaphase/anaphase transition of mitotic cell cycle / anaphase-promoting complex-dependent catabolic process / positive regulation of mitotic metaphase/anaphase transition / regulation of mitotic metaphase/anaphase transition / protein ubiquitination / cell division / nucleus / cytoplasm / cytosol Similarity search - Function
Mass: 9113.156 Da / Num. of mol.: 2 Source method: isolated from a genetically manipulated source Source: (gene. exp.) SCHIZOSACCHAROMYCES POMBE (fission yeast) Plasmid: PFBDM / Cell line (production host): High Five / Production host: TRICHOPLUSIA NI (cabbage looper) / References: UniProt: O13916
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