Entry Database : PDB / ID : 2w3f Structure visualization Downloads & linksTitle Reduced structure of the first GAF domain of Mycobacterium tuberculosis DosS ComponentsTWO COMPONENT SENSOR HISTIDINE KINASE DEVS (GAF FAMILY PROTEIN) Details Keywords TRANSFERASE / REDOX SENSOR / MYCOBACTERIUM TUBERCULOSIS / HEME / KINASE / HYPOXIA / GAF DOMAINFunction / homology Function and homology informationFunction Domain/homology Component
detection of redox state / carbon monoxide binding / nitric oxide binding / oxygen sensor activity / response to redox state / histidine kinase / phosphorelay sensor kinase activity / peptidoglycan-based cell wall / oxygen binding / protein autophosphorylation ... detection of redox state / carbon monoxide binding / nitric oxide binding / oxygen sensor activity / response to redox state / histidine kinase / phosphorelay sensor kinase activity / peptidoglycan-based cell wall / oxygen binding / protein autophosphorylation / membrane => GO:0016020 / protein dimerization activity / protein kinase activity / heme binding / magnesium ion binding / ATP binding / metal ion binding / plasma membrane / cytoplasm Similarity search - Function : / Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain / Histidine kinase / GAF domain / GAF domain / Histidine kinase domain / Histidine kinase domain profile. / GAF domain / Domain present in phytochromes and cGMP-specific phosphodiesterases. / GAF domain ... : / Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain / Histidine kinase / GAF domain / GAF domain / Histidine kinase domain / Histidine kinase domain profile. / GAF domain / Domain present in phytochromes and cGMP-specific phosphodiesterases. / GAF domain / GAF-like domain superfamily / Beta-Lactamase / Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase / Histidine kinase-like ATPases / Histidine kinase/HSP90-like ATPase / Histidine kinase/HSP90-like ATPase superfamily / 2-Layer Sandwich / Alpha Beta Similarity search - Domain/homology PROTOPORPHYRIN IX CONTAINING FE / Oxygen sensor histidine kinase response regulator DevS/DosS / Oxygen sensor histidine kinase response regulator DevS/DosS Similarity search - ComponentBiological species MYCOBACTERIUM TUBERCULOSIS (bacteria)Method X-RAY DIFFRACTION / SYNCHROTRON / MOLECULAR REPLACEMENT / Resolution : 1.6 Å DetailsAuthors Kang, B.S. / Cho, H.Y. / Cho, H.J. CitationJournal : J.Biol.Chem. / Year : 2009Title : Structural Insight Into the Heme-Based Redox Sensing by Doss from Mycobacterium Tuberculosis.Authors : Cho, H.Y. / Cho, H.J. / Kim, Y.M. / Oh, J.I. / Kang, B.S. History Deposition Nov 12, 2008 Deposition site : PDBE / Processing site : PDBERevision 1.0 Mar 10, 2009 Provider : repository / Type : Initial releaseRevision 1.1 May 8, 2011 Group : Version format complianceRevision 1.2 Jul 13, 2011 Group : Version format complianceRevision 1.3 May 8, 2024 Group : Data collection / Database references ... Data collection / Database references / Derived calculations / Other Category : chem_comp_atom / chem_comp_bond ... chem_comp_atom / chem_comp_bond / database_2 / pdbx_database_status / struct_conn / struct_site Item : _database_2.pdbx_DOI / _database_2.pdbx_database_accession ... _database_2.pdbx_DOI / _database_2.pdbx_database_accession / _pdbx_database_status.status_code_sf / _struct_conn.ptnr1_auth_comp_id / _struct_conn.ptnr1_auth_seq_id / _struct_conn.ptnr1_label_asym_id / _struct_conn.ptnr1_label_atom_id / _struct_conn.ptnr1_label_comp_id / _struct_conn.ptnr1_label_seq_id / _struct_conn.ptnr2_auth_comp_id / _struct_conn.ptnr2_auth_seq_id / _struct_conn.ptnr2_label_asym_id / _struct_conn.ptnr2_label_atom_id / _struct_conn.ptnr2_label_comp_id / _struct_conn.ptnr2_label_seq_id / _struct_site.pdbx_auth_asym_id / _struct_site.pdbx_auth_comp_id / _struct_site.pdbx_auth_seq_id
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