- PDB-2v6x: Stractural insight into the interaction between ESCRT-III and Vps4 -
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Basic information
Entry
Database: PDB / ID: 2v6x
Title
Stractural insight into the interaction between ESCRT-III and Vps4
Components
DOA4-INDEPENDENT DEGRADATION PROTEIN 4
VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN 4
Keywords
PROTEIN TRANSPORT / VACUOLE / ENDOSOME / TRANSPORT / ESCRT-III / MVB / VPS2 / VPS4 / SKD1 / VPS4B / VPS4A / CHMP2B / CHMP2A / NUCLEOTIDE-BINDING / AAA-ATPASE / ATP-BINDING / MULTIVESICULAR / VACUOLAR PROTEIN SORTING
Function / homology
Function and homology information
ESCRT IV complex / Sealing of the nuclear envelope (NE) by ESCRT-III / late endosome to lysosome transport via multivesicular body sorting pathway / intralumenal vesicle formation / Macroautophagy / protein retention in Golgi apparatus / Endosomal Sorting Complex Required For Transport (ESCRT) / ESCRT III complex / endosome transport via multivesicular body sorting pathway / ATP export ...ESCRT IV complex / Sealing of the nuclear envelope (NE) by ESCRT-III / late endosome to lysosome transport via multivesicular body sorting pathway / intralumenal vesicle formation / Macroautophagy / protein retention in Golgi apparatus / Endosomal Sorting Complex Required For Transport (ESCRT) / ESCRT III complex / endosome transport via multivesicular body sorting pathway / ATP export / late endosome to vacuole transport via multivesicular body sorting pathway / sterol metabolic process / nuclear membrane reassembly / midbody abscission / multivesicular body sorting pathway / vacuole organization / plasma membrane repair / membrane fission / late endosome to vacuole transport / ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway / multivesicular body assembly / reticulophagy / endosomal transport / nucleus organization / ATPase complex / autophagosome maturation / nuclear pore / multivesicular body / macroautophagy / autophagy / protein transport / midbody / endosome / endoplasmic reticulum / protein homodimerization activity / ATP hydrolysis activity / ATP binding / identical protein binding / membrane / plasma membrane / cytoplasm Similarity search - Function
Vacuolar protein sorting-associated protein 4, MIT domain / Phosphotransferase system, lactose/cellobiose-type IIA subunit / MIT (microtubule interacting and transport) domain / MIT domain superfamily / Vps4 oligomerisation, C-terminal / : / MIT domain / Microtubule Interacting and Trafficking molecule domain / Snf7 family / Snf7 ...Vacuolar protein sorting-associated protein 4, MIT domain / Phosphotransferase system, lactose/cellobiose-type IIA subunit / MIT (microtubule interacting and transport) domain / MIT domain superfamily / Vps4 oligomerisation, C-terminal / : / MIT domain / Microtubule Interacting and Trafficking molecule domain / Snf7 family / Snf7 / Vps4 C terminal oligomerisation domain / AAA ATPase, AAA+ lid domain / AAA+ lid domain / ATPase, AAA-type, conserved site / AAA-protein family signature. / Methane Monooxygenase Hydroxylase; Chain G, domain 1 / ATPase family associated with various cellular activities (AAA) / ATPase, AAA-type, core / ATPases associated with a variety of cellular activities / AAA+ ATPase domain / Up-down Bundle / P-loop containing nucleoside triphosphate hydrolase / Mainly Alpha Similarity search - Domain/homology
DOA4-independent degradation protein 4 / Vacuolar protein sorting-associated protein 4 Similarity search - Component
Biological species
SACCHAROMYCES CEREVISIAE (brewer's yeast)
Method
X-RAY DIFFRACTION / SYNCHROTRON / MAD / Resolution: 1.98 Å