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Yorodumi- PDB-2pjv: solution structure of hiv-1 gp41 fusion domain bound to DPC micelle -
+Open data
-Basic information
Entry | Database: PDB / ID: 2pjv | ||||||
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Title | solution structure of hiv-1 gp41 fusion domain bound to DPC micelle | ||||||
Components | Envelope glycoprotein | ||||||
Keywords | VIRAL PROTEIN / HIV / GP41 / FUSION / MEMBRANE / PROTEIN / DPC / VIRUS | ||||||
Function / homology | Function and homology information Dectin-2 family / positive regulation of plasma membrane raft polarization / positive regulation of receptor clustering / positive regulation of establishment of T cell polarity / virus-mediated perturbation of host defense response / host cell endosome membrane / clathrin-dependent endocytosis of virus by host cell / viral protein processing / fusion of virus membrane with host plasma membrane / fusion of virus membrane with host endosome membrane ...Dectin-2 family / positive regulation of plasma membrane raft polarization / positive regulation of receptor clustering / positive regulation of establishment of T cell polarity / virus-mediated perturbation of host defense response / host cell endosome membrane / clathrin-dependent endocytosis of virus by host cell / viral protein processing / fusion of virus membrane with host plasma membrane / fusion of virus membrane with host endosome membrane / viral envelope / virion attachment to host cell / host cell plasma membrane / virion membrane / structural molecule activity / membrane Similarity search - Function | ||||||
Biological species | Human immunodeficiency virus 1 | ||||||
Method | SOLUTION NMR / torsion angle dynamics | ||||||
Authors | Li, Y. / Tamm, L.K. | ||||||
Citation | Journal: Biophys.J. / Year: 2007 Title: Structure and Plasticity of the Human Immunodeficiency Virus gp41 Fusion Domain in Lipid Micelles and Bilayers. Authors: Li, Y. / Tamm, L.K. | ||||||
History |
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-Structure visualization
Structure viewer | Molecule: MolmilJmol/JSmol |
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-Downloads & links
-Download
PDBx/mmCIF format | 2pjv.cif.gz | 192.5 KB | Display | PDBx/mmCIF format |
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PDB format | pdb2pjv.ent.gz | 149.5 KB | Display | PDB format |
PDBx/mmJSON format | 2pjv.json.gz | Tree view | PDBx/mmJSON format | |
Others | Other downloads |
-Validation report
Arichive directory | https://data.pdbj.org/pub/pdb/validation_reports/pj/2pjv ftp://data.pdbj.org/pub/pdb/validation_reports/pj/2pjv | HTTPS FTP |
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-Related structure data
Similar structure data |
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-Links
-Assembly
Deposited unit |
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1 |
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NMR ensembles |
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-Components
#1: Protein/peptide | Mass: 2824.347 Da / Num. of mol.: 1 / Fragment: 23 N-terminal residues Source method: isolated from a genetically manipulated source Source: (gene. exp.) Human immunodeficiency virus 1 / Genus: Lentivirus / Strain: LAVmal / Gene: env / Plasmid: PET31b(+) / Production host: Escherichia coli (E. coli) / Strain (production host): BLR(DE3)pLysS / References: UniProt: P19551, UniProt: A1YNH3*PLUS |
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-Experimental details
-Experiment
Experiment | Method: SOLUTION NMR | ||||||||||||||||||||
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NMR experiment |
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-Sample preparation
Details |
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Sample conditions | pH: 7.4 / Pressure: ambient / Temperature: 303 K |
-NMR measurement
Radiation | Protocol: SINGLE WAVELENGTH / Monochromatic (M) / Laue (L): M | ||||||||||||||||||||
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Radiation wavelength | Relative weight: 1 | ||||||||||||||||||||
NMR spectrometer |
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-Processing
NMR software |
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Refinement | Method: torsion angle dynamics / Software ordinal: 1 | ||||||||||||||||||
NMR representative | Selection criteria: closest to the average | ||||||||||||||||||
NMR ensemble | Conformer selection criteria: structures with the lowest energy Conformers calculated total number: 38 / Conformers submitted total number: 38 |