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Yorodumi- PDB-2mug: Protective cellular immunity against P. falciparum malaria merozo... -
+Open data
-Basic information
Entry | Database: PDB / ID: 2mug | ||||||
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Title | Protective cellular immunity against P. falciparum malaria merozoite is associated with a different P7 and P8 residue orientation in the MHC-peptide-TCR complex | ||||||
Components | Serine-repeat antigen protein | ||||||
Keywords | PEPTIDE BINDING PROTEIN / Serine Repeat Antigen (SERA) | ||||||
Function / homology | Function and homology information symbiont-containing vacuole / cysteine-type peptidase activity / Hydrolases; Acting on peptide bonds (peptidases); Cysteine endopeptidases / plasma membrane Similarity search - Function | ||||||
Biological species | Plasmodium falciparum (malaria parasite P. falciparum) | ||||||
Method | SOLUTION NMR / DGSA-distance geometry simulated annealing | ||||||
Authors | Patarroyo, M. / Salazar, L. / Cifuentes, G. / Lozano, J. / Delgado, G. / Rivera, Z. / Rosas, J. / Vargas, L. | ||||||
Citation | Journal: Biochimie / Year: 2006 Title: Protective cellular immunity against P. falciparum malaria merozoites is associated with a different P7 and P8 residue orientation in the MHC-peptide-TCR complex. Authors: Patarroyo, M.E. / Salazar, L.M. / Cifuentes, G. / Lozano, J.M. / Delgado, G. / Rivera, Z. / Rosas, J. / Vargas, L.E. | ||||||
History |
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-Structure visualization
Structure viewer | Molecule: MolmilJmol/JSmol |
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-Downloads & links
-Download
PDBx/mmCIF format | 2mug.cif.gz | 132.3 KB | Display | PDBx/mmCIF format |
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PDB format | pdb2mug.ent.gz | 92.5 KB | Display | PDB format |
PDBx/mmJSON format | 2mug.json.gz | Tree view | PDBx/mmJSON format | |
Others | Other downloads |
-Validation report
Arichive directory | https://data.pdbj.org/pub/pdb/validation_reports/mu/2mug ftp://data.pdbj.org/pub/pdb/validation_reports/mu/2mug | HTTPS FTP |
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-Related structure data
Similar structure data | Similarity search - Function & homologyF&H Search |
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Other databases |
-Links
-Assembly
Deposited unit |
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1 |
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NMR ensembles |
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-Components
#1: Protein/peptide | Mass: 2432.822 Da / Num. of mol.: 1 / Fragment: UNP residues 901-920 / Source method: obtained synthetically Source: (synth.) Plasmodium falciparum (malaria parasite P. falciparum) References: UniProt: P69192 |
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-Experimental details
-Experiment
Experiment | Method: SOLUTION NMR | ||||||||||||||||
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NMR experiment |
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-Sample preparation
Details | Contents: 10 mg/mL protein, 30% trifluoroethanol/70% water / Solvent system: 30% trifluoroethanol/70% water |
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Sample | Conc.: 10 mg/mL / Component: entity-1 |
Sample conditions | pH: 3.7 / Pressure: ambient / Temperature: 295 K |
-NMR measurement
NMR spectrometer | Type: Bruker DRX / Manufacturer: Bruker / Model: DRX / Field strength: 500 MHz |
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-Processing
NMR software |
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Refinement | Method: DGSA-distance geometry simulated annealing / Software ordinal: 1 | ||||||||||||
NMR representative | Selection criteria: lowest energy | ||||||||||||
NMR ensemble | Conformer selection criteria: structures with the least restraint violations Conformers calculated total number: 50 / Conformers submitted total number: 22 |