- PDB-2ct2: Solution Structure of the RING domain of the Tripartite motif pro... -
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Basic information
Entry
Database: PDB / ID: 2ct2
Title
Solution Structure of the RING domain of the Tripartite motif protein 32
Components
Tripartite motif protein 32
Keywords
LIGASE / Tripartite motif protein 32 / Zinc-finger protein HT2A / Tat-interacting protein / RING domain / structural genomics / NPPSFA / National Project on Protein Structural and Functional Analyses / RIKEN Structural Genomics/Proteomics Initiative / RSGI
Function / homology
Function and homology information
actin ubiquitination / positive regulation of interleukin-17-mediated signaling pathway / positive regulation of chemokine (C-C motif) ligand 20 production / striated muscle myosin thick filament / positive regulation of striated muscle cell differentiation / suppression of viral release by host / free ubiquitin chain polymerization / negative regulation of toll-like receptor 4 signaling pathway / negative regulation of cilium assembly / Tat protein binding ...actin ubiquitination / positive regulation of interleukin-17-mediated signaling pathway / positive regulation of chemokine (C-C motif) ligand 20 production / striated muscle myosin thick filament / positive regulation of striated muscle cell differentiation / suppression of viral release by host / free ubiquitin chain polymerization / negative regulation of toll-like receptor 4 signaling pathway / negative regulation of cilium assembly / Tat protein binding / positive regulation of autophagosome assembly / tissue homeostasis / negative regulation of viral transcription / negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage / positive regulation of tumor necrosis factor-mediated signaling pathway / positive regulation of cell motility / positive regulation of neurogenesis / muscle cell cellular homeostasis / myosin binding / axon development / fat cell differentiation / response to starvation / protein K63-linked ubiquitination / positive regulation of proteolysis / autophagosome / response to tumor necrosis factor / protein K48-linked ubiquitination / positive regulation of autophagy / positive regulation of cell cycle / response to UV / negative regulation of fibroblast proliferation / translation initiation factor binding / Regulation of innate immune responses to cytosolic DNA / positive regulation of neuron differentiation / ubiquitin binding / RING-type E3 ubiquitin transferase / positive regulation of DNA-binding transcription factor activity / protein polyubiquitination / positive regulation of protein catabolic process / ubiquitin-protein transferase activity / : / ubiquitin protein ligase activity / Antigen processing: Ubiquitination & Proteasome degradation / protein-macromolecule adaptor activity / positive regulation of NF-kappaB transcription factor activity / ubiquitin-dependent protein catabolic process / positive regulation of cell growth / positive regulation of canonical NF-kappaB signal transduction / response to oxidative stress / transcription coactivator activity / protein ubiquitination / positive regulation of cell migration / innate immune response / centrosome / endoplasmic reticulum / mitochondrion / RNA binding / zinc ion binding / identical protein binding / nucleus / cytoplasm / cytosol Similarity search - Function
Conformer selection criteria: target function, structures with the least restraint violations Conformers calculated total number: 100 / Conformers submitted total number: 20
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