登録情報 | データベース: PDB / ID: 2bzy |
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タイトル | Homodimer of CrkL-SH3C domain |
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要素 | CRK-LIKE PROTEIN |
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キーワード | SH3 DOMAIN / CRK-LIKE / CRKL / DIMER / NUCLEAR EXPORT |
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機能・相同性 | 機能・相同性情報
positive regulation of glial cell migration / helper T cell diapedesis / cerebellar neuron development / chordate pharynx development / extrinsic component of postsynaptic membrane / postsynaptic specialization assembly / urogenital system development / parathyroid gland development / regulation of T cell migration / regulation of dendrite development ...positive regulation of glial cell migration / helper T cell diapedesis / cerebellar neuron development / chordate pharynx development / extrinsic component of postsynaptic membrane / postsynaptic specialization assembly / urogenital system development / parathyroid gland development / regulation of T cell migration / regulation of dendrite development / endothelin receptor signaling pathway / reelin-mediated signaling pathway / positive regulation of skeletal muscle acetylcholine-gated channel clustering / cranial skeletal system development / B cell apoptotic process / MET receptor recycling / cellular response to interleukin-7 / acetylcholine receptor signaling pathway / MET activates RAP1 and RAC1 / anterior/posterior pattern specification / establishment of cell polarity / Frs2-mediated activation / enzyme-linked receptor protein signaling pathway / blood vessel development / dendrite development / positive regulation of Rac protein signal transduction / outflow tract morphogenesis / regulation of cell adhesion mediated by integrin / single fertilization / fibroblast growth factor receptor signaling pathway / retinoic acid receptor signaling pathway / Erythropoietin activates RAS / positive regulation of substrate adhesion-dependent cell spreading / signaling adaptor activity / cellular response to transforming growth factor beta stimulus / JNK cascade / phosphotyrosine residue binding / Downstream signal transduction / cell chemotaxis / negative regulation of protein phosphorylation / thymus development / hippocampus development / Regulation of signaling by CBL / regulation of cell growth / neuron migration / neuromuscular junction / lipid metabolic process / cerebral cortex development / receptor tyrosine kinase binding / male gonad development / cell migration / cellular response to xenobiotic stimulus / T cell receptor signaling pathway / spermatogenesis / RNA polymerase II-specific DNA-binding transcription factor binding / Ras protein signal transduction / positive regulation of ERK1 and ERK2 cascade / intracellular signal transduction / cadherin binding / positive regulation of protein phosphorylation / negative regulation of gene expression / positive regulation of cell population proliferation / protein-containing complex / RNA binding / nucleoplasm / identical protein binding / cytosol / cytoplasm類似検索 - 分子機能 CRK, N-terminal SH3 domain / CRK, C-terminal SH3 domain / : / Variant SH3 domain / SH3 Domains / SH3 domain / SH2 domain / Src homology 2 (SH2) domain profile. / Src homology 2 domains / SH2 domain ...CRK, N-terminal SH3 domain / CRK, C-terminal SH3 domain / : / Variant SH3 domain / SH3 Domains / SH3 domain / SH2 domain / Src homology 2 (SH2) domain profile. / Src homology 2 domains / SH2 domain / Src homology 3 domains / SH3 type barrels. / SH2 domain superfamily / SH3-like domain superfamily / Src homology 3 (SH3) domain profile. / SH3 domain / Roll / Mainly Beta類似検索 - ドメイン・相同性 |
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生物種 | HOMO SAPIENS (ヒト) |
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手法 | X線回折 / 分子置換 / 解像度: 2.5 Å |
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データ登録者 | Harkiolaki, M. / Gilbert, R.J. / Jones, E.Y. / Feller, S.M. |
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引用 | ジャーナル: Structure / 年: 2006 タイトル: The C-Terminal SH3 Domain of Crkl as a Dynamic Dimerization Module Transiently Exposing a Nuclear Export Signal. 著者: Harkiolaki, M. / Gilbert, R.J. / Jones, E.Y. / Feller, S.M. |
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履歴 | 登録 | 2005年8月24日 | 登録サイト: PDBE / 処理サイト: PDBE |
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改定 1.0 | 2006年9月28日 | Provider: repository / タイプ: Initial release |
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改定 1.1 | 2019年5月22日 | Group: Data collection / Refinement description / カテゴリ: refine / Item: _refine.pdbx_ls_cross_valid_method |
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改定 1.2 | 2023年12月13日 | Group: Data collection / Database references ...Data collection / Database references / Other / Refinement description カテゴリ: chem_comp_atom / chem_comp_bond ...chem_comp_atom / chem_comp_bond / database_2 / pdbx_database_status / pdbx_initial_refinement_model Item: _database_2.pdbx_DOI / _database_2.pdbx_database_accession / _pdbx_database_status.status_code_sf |
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