Entry Database : PDB / ID : 2bwq Structure visualization Downloads & linksTitle Crystal Structure of the RIM2 C2A-domain at 1.4 angstrom Resolution ComponentsREGULATING SYNAPTIC MEMBRANE EXOCYTOSIS PROTEIN 2 Details Keywords TRANSPORT PROTEIN / C2 DOMAIN / NEUROTRANSMITTER RELEASEFunction / homology Function and homology informationFunction Domain/homology Component
regulation of calcium-dependent activation of synaptic vesicle fusion / structural constituent of presynaptic active zone / maintenance of presynaptic active zone structure / cytoskeleton of presynaptic active zone / spontaneous neurotransmitter secretion / synaptic vesicle docking / inhibitory synapse / calcium ion-regulated exocytosis of neurotransmitter / presynaptic active zone cytoplasmic component / photoreceptor ribbon synapse ... regulation of calcium-dependent activation of synaptic vesicle fusion / structural constituent of presynaptic active zone / maintenance of presynaptic active zone structure / cytoskeleton of presynaptic active zone / spontaneous neurotransmitter secretion / synaptic vesicle docking / inhibitory synapse / calcium ion-regulated exocytosis of neurotransmitter / presynaptic active zone cytoplasmic component / photoreceptor ribbon synapse / calcium-ion regulated exocytosis / positive regulation of dendrite extension / regulation of exocytosis / positive regulation of inhibitory postsynaptic potential / neurotransmitter secretion / insulin secretion / synaptic vesicle priming / regulation of synaptic vesicle exocytosis / exocytosis / positive regulation of excitatory postsynaptic potential / GABA-ergic synapse / positive regulation of synaptic transmission / cell projection / establishment of localization in cell / regulation of membrane potential / intracellular protein transport / regulation of synaptic plasticity / adenylate cyclase-modulating G protein-coupled receptor signaling pathway / small GTPase binding / protein-macromolecule adaptor activity / presynaptic membrane / transmembrane transporter binding / cell differentiation / protein domain specific binding / glutamatergic synapse / positive regulation of gene expression / protein-containing complex binding / protein-containing complex / metal ion binding Similarity search - Function Rim-like / Rab-binding domain / FYVE-type zinc finger / FYVE-type zinc finger / Rab-binding domain profile. / Zinc finger, FYVE-related / Zinc finger FYVE/FYVE-related type profile. / C2 domain / C2 domain / Protein kinase C conserved region 2 (CalB) ... Rim-like / Rab-binding domain / FYVE-type zinc finger / FYVE-type zinc finger / Rab-binding domain profile. / Zinc finger, FYVE-related / Zinc finger FYVE/FYVE-related type profile. / C2 domain / C2 domain / Protein kinase C conserved region 2 (CalB) / C2 domain / C2 domain profile. / C2 domain superfamily / PDZ domain / PDZ domain profile. / Domain present in PSD-95, Dlg, and ZO-1/2. / PDZ domain / PDZ superfamily / Zinc finger, FYVE/PHD-type / Zinc finger, RING/FYVE/PHD-type / Immunoglobulin-like / Sandwich / Mainly Beta Similarity search - Domain/homologyBiological species RATTUS NORVEGICUS (Norway rat)Method X-RAY DIFFRACTION / SYNCHROTRON / MOLECULAR REPLACEMENT / Resolution : 1.41 Å DetailsAuthors Dai, H. / Tomchick, D.R. / Garcia, J. / Sudhof, T.C. / Machius, M. / Rizo, J. CitationJournal : Biochemistry / Year : 2005Title : Crystal Structure of the Rim2 C(2)A-Domain at 1.4 A Resolution.Authors : Dai, H. / Tomchick, D.R. / Garcia, J. / Sudhof, T.C. / Machius, M. / Rizo, J. History Deposition Jul 15, 2005 Deposition site : PDBE / Processing site : PDBERevision 1.0 Oct 20, 2005 Provider : repository / Type : Initial releaseRevision 1.1 Jul 13, 2011 Group : Advisory / Version format complianceRevision 1.2 May 8, 2019 Group : Data collection / Experimental preparation / OtherCategory : exptl_crystal_grow / pdbx_database_proc / pdbx_database_statusItem : _exptl_crystal_grow.temp / _pdbx_database_status.recvd_author_approvalRevision 1.3 May 15, 2019 Group : Data collection / Experimental preparation / Category : exptl_crystal_grow / Item : _exptl_crystal_grow.methodRevision 1.4 Dec 13, 2023 Group : Data collection / Database references ... Data collection / Database references / Derived calculations / Other / Refinement description Category : chem_comp_atom / chem_comp_bond ... chem_comp_atom / chem_comp_bond / database_2 / pdbx_database_status / pdbx_initial_refinement_model / struct_site Item : _database_2.pdbx_DOI / _database_2.pdbx_database_accession ... _database_2.pdbx_DOI / _database_2.pdbx_database_accession / _pdbx_database_status.status_code_sf / _struct_site.pdbx_auth_asym_id / _struct_site.pdbx_auth_comp_id / _struct_site.pdbx_auth_seq_id
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