Entry Database : PDB / ID : 2bwl Structure visualization Downloads & linksTitle Murine angiogenin, phosphate complex ComponentsANGIOGENIN Details Keywords HYDROLASE / RIBONUCLEASE / ANGIOGENESIS / CANCERFunction / homology Function and homology informationFunction Domain/homology Component
tRNA destabilization / tRNA-specific ribonuclease activity / activation of phospholipase A2 activity / angiogenin-PRI complex / Adherens junctions interactions / diacylglycerol biosynthetic process / Hydrolases; Acting on ester bonds; Endoribonucleases producing 3'-phosphomonoesters / rRNA transcription / : / basement membrane ... tRNA destabilization / tRNA-specific ribonuclease activity / activation of phospholipase A2 activity / angiogenin-PRI complex / Adherens junctions interactions / diacylglycerol biosynthetic process / Hydrolases; Acting on ester bonds; Endoribonucleases producing 3'-phosphomonoesters / rRNA transcription / : / basement membrane / RNA nuclease activity / positive regulation of endothelial cell proliferation / actin filament polymerization / central nervous system development / positive regulation of protein secretion / negative regulation of smooth muscle cell proliferation / antimicrobial humoral immune response mediated by antimicrobial peptide / heparin binding / actin binding / antibacterial humoral response / growth cone / cytoplasmic vesicle / angiogenesis / endonuclease activity / cell differentiation / response to hypoxia / negative regulation of translation / defense response to Gram-positive bacterium / copper ion binding / innate immune response / signaling receptor binding / neuronal cell body / nucleolus / protein homodimerization activity / DNA binding / RNA binding / extracellular space / extracellular region / nucleus Similarity search - Function P-30 Protein / Ribonuclease A-like domain / Pancreatic ribonuclease / Ribonuclease A, active site / Ribonuclease A-domain / Ribonuclease A-like domain superfamily / Pancreatic ribonuclease / Pancreatic ribonuclease family signature. / Pancreatic ribonuclease / Roll / Alpha Beta Similarity search - Domain/homologyBiological species MUS MUSCULUS (house mouse)Method X-RAY DIFFRACTION / SYNCHROTRON / MOLECULAR REPLACEMENT / Resolution : 1.62 Å DetailsAuthors Holloway, D.E. / Chavali, G.B. / Hares, M.C. / Subramanian, V. / Acharya, K.R. CitationJournal : Acta Crystallogr.,Sect.D / Year : 2005Title : Structure of Murine Angiogenin: Features of the Substrate- and Cell-Binding Regions and Prospects for Inhibitor-Binding Studies.Authors : Holloway, D.E. / Chavali, G.B. / Hares, M.C. / Subramanian, V. / Acharya, K.R. History Deposition Jul 15, 2005 Deposition site : PDBE / Processing site : PDBERevision 1.0 Nov 30, 2005 Provider : repository / Type : Initial releaseRevision 1.1 May 8, 2011 Group : Version format complianceRevision 1.2 Jul 13, 2011 Group : Version format complianceRevision 1.3 Dec 13, 2023 Group : Data collection / Database references ... Data collection / Database references / Other / Refinement description Category : chem_comp_atom / chem_comp_bond ... chem_comp_atom / chem_comp_bond / database_2 / pdbx_database_status / pdbx_initial_refinement_model Item : _database_2.pdbx_DOI / _database_2.pdbx_database_accession / _pdbx_database_status.status_code_sf
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