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Yorodumi- PDB-1xy1: CRYSTAL STRUCTURE ANALYSIS OF DEAMINO-OXYTOCIN. CONFORMATIONAL FL... -
+Open data
-Basic information
Entry | Database: PDB / ID: 1xy1 | ||||||
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Title | CRYSTAL STRUCTURE ANALYSIS OF DEAMINO-OXYTOCIN. CONFORMATIONAL FLEXIBILITY AND RECEPTOR BINDING | ||||||
Components | BETA-MERCAPTOPROPIONATE-OXYTOCIN | ||||||
Keywords | HORMONE | ||||||
Function / homology | Function and homology information Vasopressin-like receptors / oxytocin receptor binding / neurohypophyseal hormone activity / V1A vasopressin receptor binding / neuropeptide hormone activity / G alpha (q) signalling events / secretory granule / response to estrogen / positive regulation of cold-induced thermogenesis / extracellular space Similarity search - Function | ||||||
Method | X-RAY DIFFRACTION / Resolution: 1.04 Å | ||||||
Authors | Husain, J. / Blundell, T.L. / Wood, S.P. / Tickle, I.J. / Cooper, S. / Pitts, J.E. | ||||||
Citation | Journal: Science / Year: 1986 Title: Crystal structure analysis of deamino-oxytocin: conformational flexibility and receptor binding. Authors: Wood, S.P. / Tickle, I.J. / Treharne, A.M. / Pitts, J.E. / Mascarenhas, Y. / Li, J.Y. / Husain, J. / Cooper, S. / Blundell, T.L. / Hruby, V.J. / Buku, A. / Fischman, A.J. / Wyssbrod, H.R. #1: Journal: Biological Organization. Macromolecular Interactions at High Resolution Year: 1987 Title: X-Ray Analysis of Deamino-Oxytocin. Conformational Flexibility and Receptor Binding Authors: Pitts, J.E. / Wood, S.P. / Tickle, I.J. / Treharne, A.M. / Mascarenhas, Y. / Li, J.Y. / Husain, J. / Cooper, S. / Blundell, T.L. / Hruby, V.J. / Wyssbrod, H.R. / Baku, A. / Fischman, A.J. #2: Journal: Crystallography in Molecular Biology / Year: 1988 Title: X-Ray Analysis of Polypeptide Hormones at (Less Than or Equal) 1 Angstrom Resolution. Anisotropic Thermal Motion and Secondary Structure of Pancreatic Polypeptide and Deamino-Oxytocin Authors: Treharne, A.M. / Wood, S.P. / Tickle, I.J. / Pitts, J.E. / Husain, J. / Glover, I.D. / Cooper, S. / Blundell, T.L. | ||||||
History |
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-Structure visualization
Structure viewer | Molecule: MolmilJmol/JSmol |
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-Downloads & links
-Download
PDBx/mmCIF format | 1xy1.cif.gz | 17.7 KB | Display | PDBx/mmCIF format |
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PDB format | pdb1xy1.ent.gz | 13.6 KB | Display | PDB format |
PDBx/mmJSON format | 1xy1.json.gz | Tree view | PDBx/mmJSON format | |
Others | Other downloads |
-Validation report
Arichive directory | https://data.pdbj.org/pub/pdb/validation_reports/xy/1xy1 ftp://data.pdbj.org/pub/pdb/validation_reports/xy/1xy1 | HTTPS FTP |
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-Related structure data
-Links
-Assembly
Deposited unit |
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1 |
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Unit cell |
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Atom site foot note | 1: THE SG ATOM OF RESIDUE MPR A 1 AND MPR B 1 IS DISORDERED. THE TWO POSSIBLE SITES FOR THIS ATOM ARE GIVEN AS ALTERNATE LOCATIONS *A* AND *B*. 2: THERMAL PARAMETERS FOR SOME HYDROGEN ATOMS WERE DEPOSITED WITH VALUES LESS THAN 0.05. CONVERSION TO UEQ GENERATES A THERMAL PARAMETER OF 0.00 BECAUSE OF PROTEIN DATA BANK FORMAT SPECIFICATION FOR THIS FIELD. | ||||||||
Noncrystallographic symmetry (NCS) | NCS oper: (Code: given Matrix: (-0.9977, -0.0662, 0.0109), Vector: |
-Components
#1: Protein/peptide | Mass: 993.182 Da / Num. of mol.: 2 Source method: isolated from a genetically manipulated source References: UniProt: P01175*PLUS #2: Water | ChemComp-HOH / | |
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-Experimental details
-Experiment
Experiment | Method: X-RAY DIFFRACTION |
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-Sample preparation
Crystal grow | *PLUS Method: other / Details: Chiu, C.C., (1969) Science, 163, 925. |
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-Data collection
Radiation | Scattering type: x-ray |
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Radiation wavelength | Relative weight: 1 |
-Processing
Software |
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Refinement | Highest resolution: 1.04 Å | ||||||||||||
Refinement step | Cycle: LAST / Highest resolution: 1.04 Å
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Refinement | *PLUS Num. reflection obs: 4681 / Rfactor obs: 0.088 | ||||||||||||
Solvent computation | *PLUS | ||||||||||||
Displacement parameters | *PLUS |