登録情報 データベース : PDB / ID : 1x9d 構造の表示 ダウンロードとリンクタイトル Crystal Structure Of Human Class I alpha-1,2-Mannosidase In Complex With Thio-Disaccharide Substrate Analogue 要素Endoplasmic reticulum mannosyl-oligosaccharide 1,2-alpha-mannosidase 詳細 キーワード HYDROLASE / mannosidase / substrate analogue / glycosyl hydrolase機能・相同性 機能・相同性情報分子機能 ドメイン・相同性 構成要素
mannoprotein catabolic process / protein alpha-1,2-demannosylation / Defective MAN1B1 causes MRT15 / mannosyl-oligosaccharide 1,2-alpha-mannosidase / mannosyl-oligosaccharide 1,2-alpha-mannosidase activity / endoplasmic reticulum quality control compartment / oligosaccharide metabolic process / protein glycosylation / ERAD pathway / ER Quality Control Compartment (ERQC) ... mannoprotein catabolic process / protein alpha-1,2-demannosylation / Defective MAN1B1 causes MRT15 / mannosyl-oligosaccharide 1,2-alpha-mannosidase / mannosyl-oligosaccharide 1,2-alpha-mannosidase activity / endoplasmic reticulum quality control compartment / oligosaccharide metabolic process / protein glycosylation / ERAD pathway / ER Quality Control Compartment (ERQC) / extracellular vesicle / cytoplasmic vesicle / Maturation of spike protein / viral protein processing / calcium ion binding / endoplasmic reticulum membrane / Golgi apparatus / endoplasmic reticulum / membrane 類似検索 - 分子機能 : / Glycoside hydrolase family 47 / Seven-hairpin glycosidases / Glycosyl hydrolase family 47 / Glycosyltransferase - #10 / Six-hairpin glycosidase-like superfamily / Glycosyltransferase / Alpha/alpha barrel / Mainly Alpha 類似検索 - ドメイン・相同性 methyl 2-S-alpha-D-mannopyranosyl-2-thio-alpha-D-mannopyranoside / 1,4-BUTANEDIOL / Endoplasmic reticulum mannosyl-oligosaccharide 1,2-alpha-mannosidase 類似検索 - 構成要素生物種 Homo sapiens (ヒト)手法 X線回折 / シンクロトロン / 分子置換 / 解像度 : 1.41 Å 詳細データ登録者 Karaveg, K. / Tempel, W. / Liu, Z.J. / Siriwardena, A. / Moremen, K.W. / Wang, B.C. 引用ジャーナル : J.Biol.Chem. / 年 : 2005タイトル : Mechanism of class 1 (glycosylhydrolase family 47) {alpha}-mannosidases involved in N-glycan processing and endoplasmic reticulum quality control.著者 : Karaveg, K. / Siriwardena, A. / Tempel, W. / Liu, Z.J. / Glushka, J. / Wang, B.C. / Moremen, K.W. 履歴 登録 2004年8月20日 登録サイト : RCSB / 処理サイト : RCSB改定 1.0 2005年2月22日 Provider : repository / タイプ : Initial release改定 1.1 2008年4月30日 Group : Version format compliance改定 1.2 2011年7月13日 Group : Version format compliance改定 1.3 2017年10月11日 Group : Refinement description / カテゴリ : softwareItem : _software.classification / _software.contact_author ... _software.classification / _software.contact_author / _software.contact_author_email / _software.date / _software.language / _software.location / _software.name / _software.type / _software.version 改定 2.0 2020年7月29日 Group : Atomic model / Data collection ... Atomic model / Data collection / Database references / Derived calculations / Non-polymer description / Structure summary カテゴリ : atom_site / chem_comp ... atom_site / chem_comp / entity / entity_name_com / pdbx_branch_scheme / pdbx_chem_comp_identifier / pdbx_entity_branch / pdbx_entity_branch_descriptor / pdbx_entity_branch_link / pdbx_entity_branch_list / pdbx_entity_nonpoly / pdbx_molecule_features / pdbx_nonpoly_scheme / pdbx_struct_conn_angle / struct_conn / struct_conn_type / struct_ref_seq_dif / struct_site / struct_site_gen Item : _atom_site.B_iso_or_equiv / _atom_site.Cartn_x ... _atom_site.B_iso_or_equiv / _atom_site.Cartn_x / _atom_site.Cartn_y / _atom_site.Cartn_z / _atom_site.auth_asym_id / _atom_site.auth_atom_id / _atom_site.auth_comp_id / _atom_site.auth_seq_id / _atom_site.label_asym_id / _atom_site.label_atom_id / _atom_site.label_comp_id / _atom_site.label_entity_id / _atom_site.type_symbol / _chem_comp.formula / _chem_comp.formula_weight / _chem_comp.id / _chem_comp.mon_nstd_flag / _chem_comp.name / _chem_comp.type / _entity.formula_weight / _entity.pdbx_description / _entity.src_method / _entity.type / _pdbx_struct_conn_angle.ptnr1_auth_asym_id / _pdbx_struct_conn_angle.ptnr1_auth_comp_id / _pdbx_struct_conn_angle.ptnr1_auth_seq_id / _pdbx_struct_conn_angle.ptnr1_label_asym_id / _pdbx_struct_conn_angle.ptnr1_label_atom_id / _pdbx_struct_conn_angle.ptnr1_label_comp_id / _pdbx_struct_conn_angle.ptnr1_label_seq_id / _pdbx_struct_conn_angle.ptnr2_label_asym_id / _pdbx_struct_conn_angle.ptnr3_auth_asym_id / _pdbx_struct_conn_angle.ptnr3_auth_comp_id / _pdbx_struct_conn_angle.ptnr3_auth_seq_id / _pdbx_struct_conn_angle.ptnr3_label_asym_id / _pdbx_struct_conn_angle.ptnr3_label_atom_id / _pdbx_struct_conn_angle.ptnr3_label_comp_id / _pdbx_struct_conn_angle.ptnr3_label_seq_id / _pdbx_struct_conn_angle.value / _struct_ref_seq_dif.details 解説 : Carbohydrate remediation / Provider : repository / タイプ : Remediation改定 2.1 2023年8月23日 Group : Data collection / Database references ... Data collection / Database references / Refinement description / Structure summary カテゴリ : chem_comp / chem_comp_atom ... chem_comp / chem_comp_atom / chem_comp_bond / database_2 / pdbx_initial_refinement_model Item : _chem_comp.pdbx_synonyms / _database_2.pdbx_DOI / _database_2.pdbx_database_accession
すべて表示 表示を減らす Remark 999 SEQUENCE THERE IS STRONG EVIDENCE FOR SPONTANEOUS N-TERMINAL TRUNCATION PRIOR TO CRYSTALLIZATION. ... SEQUENCE THERE IS STRONG EVIDENCE FOR SPONTANEOUS N-TERMINAL TRUNCATION PRIOR TO CRYSTALLIZATION. HOWEVER, THE PRECISE POSITION OF THE N-TERMINUS OF THE CRYSTALLIZING PEPTIDE HAS NOT BEEN DETERMINED.