- PDB-1wmk: Human death-associated kinase DRP-1, mutant S308D d40 -
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IDまたはキーワード:
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基本情報
登録情報
データベース: PDB / ID: 1wmk
タイトル
Human death-associated kinase DRP-1, mutant S308D d40
要素
Death-associated protein kinase 2
キーワード
TRANSFERASE / protein kinase / autoinhibitory helix
機能・相同性
機能・相同性情報
autophagosome lumen / regulation of intrinsic apoptotic signaling pathway / positive regulation of eosinophil chemotaxis / Caspase activation via Dependence Receptors in the absence of ligand / positive regulation of neutrophil chemotaxis / anoikis / regulation of autophagy / cytoplasmic vesicle / regulation of apoptotic process / protein autophosphorylation ...autophagosome lumen / regulation of intrinsic apoptotic signaling pathway / positive regulation of eosinophil chemotaxis / Caspase activation via Dependence Receptors in the absence of ligand / positive regulation of neutrophil chemotaxis / anoikis / regulation of autophagy / cytoplasmic vesicle / regulation of apoptotic process / protein autophosphorylation / non-specific serine/threonine protein kinase / calmodulin binding / intracellular signal transduction / positive regulation of apoptotic process / protein phosphorylation / intracellular membrane-bounded organelle / protein serine kinase activity / protein serine/threonine kinase activity / apoptotic process / Golgi apparatus / ATP binding / identical protein binding / nucleus / cytoplasm 類似検索 - 分子機能
Single helix bin / Single alpha-helices involved in coiled-coils or other helix-helix interfaces / Transferase(Phosphotransferase) domain 1 / Transferase(Phosphotransferase); domain 1 / Phosphorylase Kinase; domain 1 / Phosphorylase Kinase; domain 1 / Serine/threonine-protein kinase, active site / Serine/Threonine protein kinases active-site signature. / Protein kinase domain / Serine/Threonine protein kinases, catalytic domain ...Single helix bin / Single alpha-helices involved in coiled-coils or other helix-helix interfaces / Transferase(Phosphotransferase) domain 1 / Transferase(Phosphotransferase); domain 1 / Phosphorylase Kinase; domain 1 / Phosphorylase Kinase; domain 1 / Serine/threonine-protein kinase, active site / Serine/Threonine protein kinases active-site signature. / Protein kinase domain / Serine/Threonine protein kinases, catalytic domain / Protein kinase, ATP binding site / Protein kinases ATP-binding region signature. / Protein kinase domain profile. / Protein kinase domain / Protein kinase-like domain superfamily / Up-down Bundle / 2-Layer Sandwich / Orthogonal Bundle / Mainly Alpha / Alpha Beta 類似検索 - ドメイン・相同性
A: Death-associated protein kinase 2 E: Death-associated protein kinase 2 C: Death-associated protein kinase 2 B: Death-associated protein kinase 2 F: Death-associated protein kinase 2 D: Death-associated protein kinase 2 H: Death-associated protein kinase 2 G: Death-associated protein kinase 2
解像度: 3.6→20 Å / Cor.coef. Fo:Fc: 0.886 / Cor.coef. Fo:Fc free: 0.873 / SU B: 53.183 / SU ML: 0.732 Isotropic thermal model: GROUP B FACTOR REFINEMENT IN CNS, OVERALL B FACTOR REFINEMENT IN REFMAC5 交差検証法: THROUGHOUT / σ(F): -3 / ESU R Free: 0.814 / 立体化学のターゲット値: MAXIMUM LIKELIHOOD 詳細: HYDROGENS HAVE BEEN ADDED IN THE RIDING POSITIONS. GROUP B FACTOR REFINEMENT IN CNS, OVERALL B FACTOR REFINEMENT IN REFMAC5
Rfactor
反射数
%反射
Selection details
Rfree
0.29577
1864
5 %
RANDOM
Rwork
0.27633
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all
0.2773
37254
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obs
0.2773
37254
99.97 %
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溶媒の処理
イオンプローブ半径: 0.8 Å / 減衰半径: 0.8 Å / VDWプローブ半径: 1.2 Å / 溶媒モデル: MASK