[English] 日本語
![](img/lk-miru.gif)
- PDB-1tgb: CRYSTAL STRUCTURE OF BOVINE TRYPSINOGEN AT 1.8 ANGSTROMS RESOLUTI... -
+
Open data
-
Basic information
Entry | Database: PDB / ID: 1tgb | ||||||
---|---|---|---|---|---|---|---|
Title | CRYSTAL STRUCTURE OF BOVINE TRYPSINOGEN AT 1.8 ANGSTROMS RESOLUTION. II. CRYSTALLOGRAPHIC REFINEMENT, REFINED CRYSTAL STRUCTURE AND COMPARISON WITH BOVINE TRYPSIN | ||||||
![]() | TRYPSINOGEN | ||||||
![]() | HYDROLASE ZYMOGEN (SERINE PROTEINASE) | ||||||
Function / homology | ![]() trypsin / serpin family protein binding / serine protease inhibitor complex / digestion / endopeptidase activity / serine-type endopeptidase activity / proteolysis / extracellular space / metal ion binding Similarity search - Function | ||||||
Biological species | ![]() ![]() | ||||||
Method | ![]() | ||||||
![]() | Bode, W. / Fehlhammer, H. / Huber, R. | ||||||
![]() | ![]() Title: Crystal structure of bovine trypsinogen at 1-8 A resolution. II. Crystallographic refinement, refined crystal structure and comparison with bovine trypsin. Authors: Fehlhammer, H. / Bode, W. / Huber, R. #1: ![]() Title: Crystal Structure of Bovine Trypsinogen at 1.8 Angstroms Resolution. I. Data Collection, Application of Patterson Search Techniques and Preliminary Structural Interpretation Authors: Bode, W. / Fehlhammer, H. / Huber, R. #2: ![]() Title: Low-Temperature Protein Crystallography. Temperature Factor, Mosaic Spread, Extinction and Diffuse Scattering in Two Examples. Bovine Trypsinogen and Fc Fragment Authors: Singh, T.P. / Bode, W. / Huber, R. #3: ![]() Title: Structural Basis of the Activation and Action of Trypsin Authors: Huber, R. / Bode, W. #4: ![]() Title: Crystal Structure Analysis and Refinement of Two Variants of Trigonal Trypsinogen Authors: Bode, W. / Huber, R. | ||||||
History |
|
-
Structure visualization
Structure viewer | Molecule: ![]() ![]() |
---|
-
Downloads & links
-
Download
PDBx/mmCIF format | ![]() | 55.3 KB | Display | ![]() |
---|---|---|---|---|
PDB format | ![]() | 39.6 KB | Display | ![]() |
PDBx/mmJSON format | ![]() | Tree view | ![]() | |
Others | ![]() |
-Validation report
Summary document | ![]() | 365.3 KB | Display | ![]() |
---|---|---|---|---|
Full document | ![]() | 377.2 KB | Display | |
Data in XML | ![]() | 7.4 KB | Display | |
Data in CIF | ![]() | 10.8 KB | Display | |
Arichive directory | ![]() ![]() | HTTPS FTP |
-Related structure data
Similar structure data |
---|
-
Links
-
Assembly
Deposited unit | ![]()
| ||||||||
---|---|---|---|---|---|---|---|---|---|
1 |
| ||||||||
Unit cell |
| ||||||||
Atom site foot note | 1: THESE ATOMS WERE NOT FOUND IN THE ELECTRON DENSITY MAP. THEIR COORDINATES WERE GENERATED USING STEREOCHEMICAL CRITERIA. | ||||||||
Components on special symmetry positions |
|
-
Components
#1: Protein | Mass: 24012.953 Da / Num. of mol.: 1 Source method: isolated from a genetically manipulated source Source: (gene. exp.) ![]() ![]() |
---|---|
#2: Chemical | ChemComp-CA / |
#3: Water | ChemComp-HOH / |
-Experimental details
-Experiment
Experiment | Method: ![]() |
---|
-
Sample preparation
Crystal | Density Matthews: 2 Å3/Da / Density % sol: 38.37 % |
---|---|
Crystal grow | *PLUS Method: other / Details: Bode, W., (1976) J. Mol. Biol., 106, 325. |
-Data collection
Reflection | *PLUS Highest resolution: 1.8 Å / Num. obs: 15000 / Num. measured all: 45000 |
---|
-
Processing
Refinement | Highest resolution: 1.8 Å Details: THE TEMPERATURE FACTOR FIELD OF THE ATOM AND HETATM RECORDS CONTAINS THE ATOMIC RADIUS WHICH HAS BEEN TENTATIVELY REFINED. THE OCCUPANCY FACTORS (WEIGHTS) HAVE BEEN REFINED ONLY FOR THE SOLVENT ATOMS. | ||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Refinement step | Cycle: LAST / Highest resolution: 1.8 Å
| ||||||||||||
Refinement | *PLUS σ(I): 2 / Rfactor all: 0.38 / Rfactor obs: 0.27 | ||||||||||||
Solvent computation | *PLUS | ||||||||||||
Displacement parameters | *PLUS |