[English] 日本語
Yorodumi- PDB-1tgb: CRYSTAL STRUCTURE OF BOVINE TRYPSINOGEN AT 1.8 ANGSTROMS RESOLUTI... -
+Open data
-Basic information
Entry | Database: PDB / ID: 1tgb | ||||||
---|---|---|---|---|---|---|---|
Title | CRYSTAL STRUCTURE OF BOVINE TRYPSINOGEN AT 1.8 ANGSTROMS RESOLUTION. II. CRYSTALLOGRAPHIC REFINEMENT, REFINED CRYSTAL STRUCTURE AND COMPARISON WITH BOVINE TRYPSIN | ||||||
Components | TRYPSINOGEN | ||||||
Keywords | HYDROLASE ZYMOGEN (SERINE PROTEINASE) | ||||||
Function / homology | Function and homology information trypsin / serpin family protein binding / serine protease inhibitor complex / digestion / endopeptidase activity / serine-type endopeptidase activity / proteolysis / extracellular space / metal ion binding Similarity search - Function | ||||||
Biological species | Bos taurus (cattle) | ||||||
Method | X-RAY DIFFRACTION / Resolution: 1.8 Å | ||||||
Authors | Bode, W. / Fehlhammer, H. / Huber, R. | ||||||
Citation | Journal: J.Mol.Biol. / Year: 1977 Title: Crystal structure of bovine trypsinogen at 1-8 A resolution. II. Crystallographic refinement, refined crystal structure and comparison with bovine trypsin. Authors: Fehlhammer, H. / Bode, W. / Huber, R. #1: Journal: J.Mol.Biol. / Year: 1976 Title: Crystal Structure of Bovine Trypsinogen at 1.8 Angstroms Resolution. I. Data Collection, Application of Patterson Search Techniques and Preliminary Structural Interpretation Authors: Bode, W. / Fehlhammer, H. / Huber, R. #2: Journal: Acta Crystallogr.,Sect.B / Year: 1980 Title: Low-Temperature Protein Crystallography. Temperature Factor, Mosaic Spread, Extinction and Diffuse Scattering in Two Examples. Bovine Trypsinogen and Fc Fragment Authors: Singh, T.P. / Bode, W. / Huber, R. #3: Journal: Acc.Chem.Res. / Year: 1978 Title: Structural Basis of the Activation and Action of Trypsin Authors: Huber, R. / Bode, W. #4: Journal: FEBS Lett. / Year: 1978 Title: Crystal Structure Analysis and Refinement of Two Variants of Trigonal Trypsinogen Authors: Bode, W. / Huber, R. | ||||||
History |
|
-Structure visualization
Structure viewer | Molecule: MolmilJmol/JSmol |
---|
-Downloads & links
-Download
PDBx/mmCIF format | 1tgb.cif.gz | 51.5 KB | Display | PDBx/mmCIF format |
---|---|---|---|---|
PDB format | pdb1tgb.ent.gz | 40.8 KB | Display | PDB format |
PDBx/mmJSON format | 1tgb.json.gz | Tree view | PDBx/mmJSON format | |
Others | Other downloads |
-Validation report
Arichive directory | https://data.pdbj.org/pub/pdb/validation_reports/tg/1tgb ftp://data.pdbj.org/pub/pdb/validation_reports/tg/1tgb | HTTPS FTP |
---|
-Related structure data
Similar structure data |
---|
-Links
-Assembly
Deposited unit |
| ||||||||
---|---|---|---|---|---|---|---|---|---|
1 |
| ||||||||
Unit cell |
| ||||||||
Atom site foot note | 1: THESE ATOMS WERE NOT FOUND IN THE ELECTRON DENSITY MAP. THEIR COORDINATES WERE GENERATED USING STEREOCHEMICAL CRITERIA. | ||||||||
Components on special symmetry positions |
|
-Components
#1: Protein | Mass: 24012.953 Da / Num. of mol.: 1 Source method: isolated from a genetically manipulated source Source: (gene. exp.) Bos taurus (cattle) / References: UniProt: P00760 |
---|---|
#2: Chemical | ChemComp-CA / |
#3: Water | ChemComp-HOH / |
-Experimental details
-Experiment
Experiment | Method: X-RAY DIFFRACTION |
---|
-Sample preparation
Crystal | Density Matthews: 2 Å3/Da / Density % sol: 38.37 % |
---|---|
Crystal grow | *PLUS Method: other / Details: Bode, W., (1976) J. Mol. Biol., 106, 325. |
-Data collection
Reflection | *PLUS Highest resolution: 1.8 Å / Num. obs: 15000 / Num. measured all: 45000 |
---|
-Processing
Refinement | Highest resolution: 1.8 Å Details: THE TEMPERATURE FACTOR FIELD OF THE ATOM AND HETATM RECORDS CONTAINS THE ATOMIC RADIUS WHICH HAS BEEN TENTATIVELY REFINED. THE OCCUPANCY FACTORS (WEIGHTS) HAVE BEEN REFINED ONLY FOR THE SOLVENT ATOMS. | ||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Refinement step | Cycle: LAST / Highest resolution: 1.8 Å
| ||||||||||||
Refinement | *PLUS σ(I): 2 / Rfactor all: 0.38 / Rfactor obs: 0.27 | ||||||||||||
Solvent computation | *PLUS | ||||||||||||
Displacement parameters | *PLUS |