[English] 日本語
Yorodumi- PDB-1san: THE DES(1-6)ANTENNAPEDIA HOMEODOMAIN: COMPARISON OF THE NMR SOLUT... -
+Open data
-Basic information
Entry | Database: PDB / ID: 1san | ||||||
---|---|---|---|---|---|---|---|
Title | THE DES(1-6)ANTENNAPEDIA HOMEODOMAIN: COMPARISON OF THE NMR SOLUTION STRUCTURE AND THE DNA BINDING AFFINITY WITH THE INTACT ANTENNAPEDIA HOMEODOMAIN | ||||||
Components | ANTENNAPEDIA PROTEIN | ||||||
Keywords | DNA BINDING PROTEIN / DNA-BINDING PROTEIN | ||||||
Function / homology | Function and homology information specification of segmental identity, antennal segment / specification of segmental identity, thorax / neuroblast development / muscle cell fate specification / lymph gland development / ventral cord development / anterior/posterior axis specification / anterior/posterior pattern specification / midgut development / regulation of neurogenesis ...specification of segmental identity, antennal segment / specification of segmental identity, thorax / neuroblast development / muscle cell fate specification / lymph gland development / ventral cord development / anterior/posterior axis specification / anterior/posterior pattern specification / midgut development / regulation of neurogenesis / heart development / sequence-specific DNA binding / DNA-binding transcription factor activity, RNA polymerase II-specific / RNA polymerase II cis-regulatory region sequence-specific DNA binding / negative regulation of transcription by RNA polymerase II / positive regulation of transcription by RNA polymerase II / DNA binding / nucleus / cytoplasm Similarity search - Function | ||||||
Biological species | Drosophila melanogaster (fruit fly) | ||||||
Method | SOLUTION NMR | ||||||
Authors | Qian, Y.Q. / Resendez-Perez, D. / Gehring, W.J. / Wuthrich, K. | ||||||
Citation | Journal: Proc.Natl.Acad.Sci.USA / Year: 1994 Title: The des(1-6)antennapedia homeodomain: comparison of the NMR solution structure and the DNA-binding affinity with the intact Antennapedia homeodomain. Authors: Qian, Y.Q. / Resendez-Perez, D. / Gehring, W.J. / Wuthrich, K. #1: Journal: J.Mol.Biol. / Year: 1991 Title: Structure Determination of the Antp(C39->S) Homeodomain from Nuclear Magnetic Resonance Data in Solution Using a Novel Strategy for the Structure Calculation with the Programs Diana, Caliba, Habas and Glomsa Authors: Guntert, P. / Qian, Y.-Q. / Otting, G. / Muller, M. / Gehring, W.J. / Wuthrich, K. #2: Journal: Cell(Cambridge,Mass.) / Year: 1989 Title: The Structure of the Antennapedia Homeodomain Determined by NMR Spectroscopy in Solution: Comparison with Prokaryotic Repressors Authors: Qian, Y.-Q. / Billeter, M. / Otting, G. / Muller, M. / Gehring, W.J. / Wuthrich, K. #3: Journal: J.Mol.Biol. / Year: 1990 Title: Determination of the Three-Dimensional Structure of the Antennapedia Homeodomain from Drosophila in Solution by 1H Nuclear Magnetic Resonance Spectroscopy Authors: Billeter, M. / Qian, Y.-Q. / Otting, G. / Muller, M. / Gehring, W.J. / Wuthrich, K. | ||||||
History |
|
-Structure visualization
Structure viewer | Molecule: MolmilJmol/JSmol |
---|
-Downloads & links
-Download
PDBx/mmCIF format | 1san.cif.gz | 486.8 KB | Display | PDBx/mmCIF format |
---|---|---|---|---|
PDB format | pdb1san.ent.gz | 415.1 KB | Display | PDB format |
PDBx/mmJSON format | 1san.json.gz | Tree view | PDBx/mmJSON format | |
Others | Other downloads |
-Validation report
Summary document | 1san_validation.pdf.gz | 356.8 KB | Display | wwPDB validaton report |
---|---|---|---|---|
Full document | 1san_full_validation.pdf.gz | 477.8 KB | Display | |
Data in XML | 1san_validation.xml.gz | 19.1 KB | Display | |
Data in CIF | 1san_validation.cif.gz | 33.1 KB | Display | |
Arichive directory | https://data.pdbj.org/pub/pdb/validation_reports/sa/1san ftp://data.pdbj.org/pub/pdb/validation_reports/sa/1san | HTTPS FTP |
-Related structure data
Similar structure data |
---|
-Links
-Assembly
Deposited unit |
| |||||||||
---|---|---|---|---|---|---|---|---|---|---|
1 |
| |||||||||
NMR ensembles |
|
-Components
#1: Protein | Mass: 7875.151 Da / Num. of mol.: 1 Source method: isolated from a genetically manipulated source Source: (gene. exp.) Drosophila melanogaster (fruit fly) / Organ: FRUIT / Production host: Escherichia coli (E. coli) / References: UniProt: P02833 |
---|
-Experimental details
-Experiment
Experiment | Method: SOLUTION NMR |
---|
-Processing
NMR software | Name: DIANA / Developer: GUNTERT,BRAUN,WUTHRICH / Classification: refinement |
---|---|
NMR ensemble | Conformers submitted total number: 20 |