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Yorodumi- PDB-1pos: CRYSTAL STRUCTURE OF A NOVEL DISULFIDE-LINKED "TREFOIL" MOTIF FOU... -
+Open data
-Basic information
Entry | Database: PDB / ID: 1pos | |||||||||
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Title | CRYSTAL STRUCTURE OF A NOVEL DISULFIDE-LINKED "TREFOIL" MOTIF FOUND IN A LARGE FAMILY OF PUTATIVE GROWTH FACTORS | |||||||||
Components | PORCINE PANCREATIC SPASMOLYTIC POLYPEPTIDE | |||||||||
Keywords | GROWTH FACTOR | |||||||||
Function / homology | Function and homology information CXCR4 chemokine receptor binding / negative regulation of gastric acid secretion / maintenance of gastrointestinal epithelium / chemokine-mediated signaling pathway / growth factor activity / extracellular space Similarity search - Function | |||||||||
Biological species | Sus scrofa (pig) | |||||||||
Method | X-RAY DIFFRACTION / Resolution: 2.6 Å | |||||||||
Authors | De, A. / Brown, D. / Gorman, M. / Carr, M. / Sanderson, M.R. / Freemont, P.S. | |||||||||
Citation | Journal: Proc.Natl.Acad.Sci.USA / Year: 1994 Title: Crystal structure of a disulfide-linked "trefoil" motif found in a large family of putative growth factors. Authors: De, A. / Brown, D.G. / Gorman, M.A. / Carr, M. / Sanderson, M.R. / Freemont, P.S. #1: Journal: J.Mol.Biol. / Year: 1992 Title: Crystallization and Preliminary X-Ray Diffraction Studies of Pancreatic Spasmolytic Polypeptide Authors: Gorman, M.A. / De, A. / Freemont, P.S. | |||||||||
History |
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-Structure visualization
Structure viewer | Molecule: MolmilJmol/JSmol |
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-Downloads & links
-Download
PDBx/mmCIF format | 1pos.cif.gz | 17.4 KB | Display | PDBx/mmCIF format |
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PDB format | pdb1pos.ent.gz | 8.4 KB | Display | PDB format |
PDBx/mmJSON format | 1pos.json.gz | Tree view | PDBx/mmJSON format | |
Others | Other downloads |
-Validation report
Arichive directory | https://data.pdbj.org/pub/pdb/validation_reports/po/1pos ftp://data.pdbj.org/pub/pdb/validation_reports/po/1pos | HTTPS FTP |
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-Related structure data
Similar structure data |
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-Links
-Assembly
Deposited unit |
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1 |
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2 |
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Unit cell |
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-Components
#1: Protein | Mass: 11735.303 Da / Num. of mol.: 2 Source method: isolated from a genetically manipulated source Source: (gene. exp.) Sus scrofa (pig) / References: UniProt: P01359 |
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-Experimental details
-Experiment
Experiment | Method: X-RAY DIFFRACTION |
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-Sample preparation
Crystal | Density Matthews: 3.85 Å3/Da / Density % sol: 68.03 % | |||||||||||||||||||||||||
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Crystal grow | *PLUS Temperature: 20 ℃ / pH: 7 / Method: vapor diffusion, hanging drop | |||||||||||||||||||||||||
Components of the solutions | *PLUS
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-Data collection
Radiation | Scattering type: x-ray |
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Radiation wavelength | Relative weight: 1 |
Reflection | *PLUS Highest resolution: 2.6 Å / Num. obs: 10739 / % possible obs: 89.9 % / Rmerge(I) obs: 0.08 |
-Processing
Software |
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Refinement | Rfactor Rwork: 0.219 / Rfactor obs: 0.219 / Highest resolution: 2.6 Å | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Refinement step | Cycle: LAST / Highest resolution: 2.6 Å
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Refine LS restraints |
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Software | *PLUS Name: X-PLOR / Classification: refinement | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Refinement | *PLUS Highest resolution: 2.6 Å / Rfactor obs: 0.219 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Solvent computation | *PLUS | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Displacement parameters | *PLUS | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Refine LS restraints | *PLUS Type: x_angle_d / Dev ideal: 1.6 |