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Open data
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Basic information
Entry | Database: PDB / ID: 1pen | ||||||
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Title | ALPHA-CONOTOXIN PNI1 | ||||||
![]() | ALPHA-CONOTOXIN PNIA | ||||||
![]() | NEUROTOXIN / ACETYLCHOLINE RECEPTOR / POSTSYNAPTIC / ANTAGONIST / ACETYLCHOLINE RECEPTOR INHIBITOR | ||||||
Function / homology | Conotoxin, alpha-type, conserved site / Alpha-conotoxin family signature. / host cell postsynaptic membrane / acetylcholine receptor inhibitor activity / ion channel regulator activity / toxin activity / extracellular region / Alpha-conotoxin PnIA![]() | ||||||
Biological species | ![]() | ||||||
Method | ![]() | ||||||
![]() | Hu, S.-H. / Gehrmann, J. / Guddat, L.W. / Alewood, P.F. / Craik, D.J. / Martin, J.L. | ||||||
![]() | ![]() Title: The 1.1 A crystal structure of the neuronal acetylcholine receptor antagonist, alpha-conotoxin PnIA from Conus pennaceus. Authors: Hu, S.H. / Gehrmann, J. / Guddat, L.W. / Alewood, P.F. / Craik, D.J. / Martin, J.L. #1: ![]() Title: Snb: Crystal Structure Determination Via Shake-and-Bake Authors: Miller, R. / Gallo, S.M. / Khalak, H.G. / Weeks, C.M. #2: ![]() Title: New Mollusc-Specific Alpha-Conotoxins Block Aplysia Neuronal Acetylcholine Receptors Authors: Fainzilber, M. / Hasson, A. / Oren, R. / Burlingame, A.L. / Gordon, D. / Spira, M.E. / Zlotkin, E. | ||||||
History |
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Structure visualization
Structure viewer | Molecule: ![]() ![]() |
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Downloads & links
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Download
PDBx/mmCIF format | ![]() | 9 KB | Display | ![]() |
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PDB format | ![]() | 6.2 KB | Display | ![]() |
PDBx/mmJSON format | ![]() | Tree view | ![]() | |
Others | ![]() |
-Validation report
Summary document | ![]() | 347 KB | Display | ![]() |
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Full document | ![]() | 347 KB | Display | |
Data in XML | ![]() | 1.5 KB | Display | |
Data in CIF | ![]() | 1.9 KB | Display | |
Arichive directory | ![]() ![]() | HTTPS FTP |
-Related structure data
Similar structure data |
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Links
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Assembly
Deposited unit | ![]()
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Unit cell |
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Components
#1: Protein/peptide | Mass: 1625.849 Da / Num. of mol.: 1 Source method: isolated from a genetically manipulated source Source: (gene. exp.) ![]() |
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#2: Water | ChemComp-HOH / |
-Experimental details
-Experiment
Experiment | Method: ![]() |
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Sample preparation
Crystal | Density % sol: 12 % | ||||||||||||||||||||||||||||||
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Crystal grow | pH: 8 / Details: pH 8.0 | ||||||||||||||||||||||||||||||
Crystal grow | *PLUS Temperature: 14 ℃ / Method: vapor diffusion, hanging drop / Details: used to seeding | ||||||||||||||||||||||||||||||
Components of the solutions | *PLUS
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-Data collection
Diffraction | Mean temperature: 289 K |
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Diffraction source | Wavelength: 1.5418 |
Detector | Type: RIGAKU RAXIS IIC / Detector: IMAGE PLATE / Date: Sep 28, 1995 |
Radiation | Monochromator: YALE MIRRORS / Monochromatic (M) / Laue (L): M / Scattering type: x-ray |
Radiation wavelength | Wavelength: 1.5418 Å / Relative weight: 1 |
Reflection | Resolution: 1.1→50 Å / Num. obs: 3459 / % possible obs: 94 % / Observed criterion σ(I): 1 / Redundancy: 4.7 % / Rmerge(I) obs: 0.08 |
Reflection | *PLUS Num. measured all: 16298 / Rmerge(I) obs: 0.08 |
Reflection shell | *PLUS Highest resolution: 1.1 Å / Lowest resolution: 1.14 Å / % possible obs: 80 % / Rmerge(I) obs: 0.24 |
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Processing
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Refinement | Resolution: 1.1→6.1 Å / σ(F): 2
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Displacement parameters | Biso mean: 7.6 Å2 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Refine analyze | Luzzati coordinate error obs: 0.1 Å | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Refinement step | Cycle: LAST / Resolution: 1.1→6.1 Å
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Refine LS restraints |
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Software | *PLUS Name: ![]() | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Refine LS restraints | *PLUS
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