[English] 日本語
![](img/lk-miru.gif)
- PDB-1myn: SOLUTION STRUCTURE OF DROSOMYCIN, THE FIRST INDUCIBLE ANTIFUNGAL ... -
+
Open data
-
Basic information
Entry | Database: PDB / ID: 1myn | ||||||
---|---|---|---|---|---|---|---|
Title | SOLUTION STRUCTURE OF DROSOMYCIN, THE FIRST INDUCIBLE ANTIFUNGAL PROTEIN FROM INSECTS, NMR, 15 STRUCTURES | ||||||
![]() | DROSOMYCIN | ||||||
![]() | SIGNAL PROTEIN / DROSOMYCIN / INSECT IMMUNITY / ANTIFUNGAL / CSALPHA-BETA MOTIF | ||||||
Function / homology | ![]() antifungal humoral response / defense response to protozoan / defense response to fungus / response to bacterium / defense response / response to wounding / antimicrobial humoral immune response mediated by antimicrobial peptide / antibacterial humoral response / defense response to Gram-negative bacterium / killing of cells of another organism / extracellular space Similarity search - Function | ||||||
Biological species | ![]() ![]() | ||||||
Method | SOLUTION NMR / DISTANCE GEOMETRY, RESTRAINED SIMULATED ANNEALING, ENERGY MINIMIZATION | ||||||
![]() | Landon, C. / Sodano, P. / Hetru, C. / Hoffmann, J.A. / Ptak, M. | ||||||
![]() | ![]() Title: Solution structure of drosomycin, the first inducible antifungal protein from insects. Authors: Landon, C. / Sodano, P. / Hetru, C. / Hoffmann, J. / Ptak, M. #1: ![]() Title: Determination of the Disulfide Array of the First Inducible Antifungal Peptide from Insects: Drosomycin from Drosophila Melanogaster Authors: Michaut, L. / Fehlbaum, P. / Moniatte, M. / Van Dorsselaer, A. / Reichhart, J.M. / Bulet, P. #2: ![]() Title: Insect Immunity. Septic Injury of Drosophila Induces the Synthesis of a Potent Antifungal Peptide with Sequence Homology to Plant Antifungal Peptides Authors: Fehlbaum, P. / Bulet, P. / Michaut, L. / Lagueux, M. / Broekaert, W.F. / Hetru, C. / Hoffmann, J.A. | ||||||
History |
|
-
Structure visualization
Structure viewer | Molecule: ![]() ![]() |
---|
-
Downloads & links
-
Download
PDBx/mmCIF format | ![]() | 193.7 KB | Display | ![]() |
---|---|---|---|---|
PDB format | ![]() | 165.2 KB | Display | ![]() |
PDBx/mmJSON format | ![]() | Tree view | ![]() | |
Others | ![]() |
-Validation report
Summary document | ![]() | 351.7 KB | Display | ![]() |
---|---|---|---|---|
Full document | ![]() | 449.9 KB | Display | |
Data in XML | ![]() | 15.9 KB | Display | |
Data in CIF | ![]() | 25.2 KB | Display | |
Arichive directory | ![]() ![]() | HTTPS FTP |
-Related structure data
Similar structure data |
---|
-
Links
-
Assembly
Deposited unit | ![]()
| |||||||||
---|---|---|---|---|---|---|---|---|---|---|
1 |
| |||||||||
NMR ensembles |
|
-
Components
#1: Protein/peptide | Mass: 4905.582 Da / Num. of mol.: 1 Source method: isolated from a genetically manipulated source Source: (gene. exp.) ![]() ![]() ![]() ![]() |
---|
-Experimental details
-Experiment
Experiment | Method: SOLUTION NMR | ||||||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
NMR experiment |
|
-
Sample preparation
Sample conditions | pH: 4.0 / Temperature: 293 K |
---|---|
Crystal grow | *PLUS Method: other / Details: NMR |
-NMR measurement
NMR spectrometer | Type: Bruker AMX500 / Manufacturer: Bruker / Model: AMX500 / Field strength: 500 MHz |
---|
-
Processing
Software |
| ||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
NMR software |
| ||||||||||||
Refinement | Method: DISTANCE GEOMETRY, RESTRAINED SIMULATED ANNEALING, ENERGY MINIMIZATION Software ordinal: 1 Details: THE 30 BEST STRUCTURES FROM THE 200 GENERATED WITH THE DIANA PROGRAM WERE REFINED WITH A SIMULATED ANNEALING/ENERGY MINIMIZATION PROTOCOL USING THE X-PLOR COMPUTER PROGRAM. | ||||||||||||
NMR ensemble | Conformer selection criteria: NUMBER OF RESIDUAL VIOLATIONS AND INTERNAL GEOMETRY Conformers calculated total number: 30 / Conformers submitted total number: 15 |