+Open data
-Basic information
Entry | Database: PDB / ID: 1gib | ||||||
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Title | MU-CONOTOXIN GIIIB, NMR | ||||||
Components | MU-CONOTOXIN GIIIB | ||||||
Keywords | NEUROTOXIN / CONOTOXIN / SODIUM CHANNEL INHIBITOR | ||||||
Function / homology | Mu-Conotoxin / Conotoxin, mu-type / Mu-conotoxin family signature. / sodium channel inhibitor activity / : / toxin activity / extracellular region / Mu-conotoxin GIIIB Function and homology information | ||||||
Biological species | Conus geographus (geography cone) | ||||||
Method | SOLUTION NMR | ||||||
Authors | Hill, J.M. / Alewood, P.F. / Craik, D.J. | ||||||
Citation | Journal: Biochemistry / Year: 1996 Title: Three-dimensional solution structure of mu-conotoxin GIIIB, a specific blocker of skeletal muscle sodium channels. Authors: Hill, J.M. / Alewood, P.F. / Craik, D.J. #1: Journal: Biochemistry / Year: 1992 Title: Structure-Activity Relationships of Mu-Conotoxin Giiia: Structure Determination of Active and Inactive Sodium Channel Blocker Peptides by NMR and Simulated Annealing Calculations Authors: Wakamatsu, K. / Kohda, D. / Hatanaka, H. / Lancelin, J.M. / Ishida, Y. / Oya, M. / Nakamura, H. / Inagaki, F. / Sato, K. #2: Journal: FEBS Lett. / Year: 1991 Title: Solution Structure of Mu-Conotoxin Giiia Analysed by 2D-NMR and Distance Geometry Calculations Authors: Ott, K.H. / Becker, S. / Gordon, R.D. / Ruterjans, H. #3: Journal: Biochemistry / Year: 1991 Title: Tertiary Structure of Conotoxin Giiia in Aqueous Solution Authors: Lancelin, J.M. / Kohda, D. / Tate, S. / Yanagawa, Y. / Abe, T. / Satake, M. / Inagaki, F. | ||||||
History |
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-Structure visualization
Structure viewer | Molecule: MolmilJmol/JSmol |
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-Downloads & links
-Download
PDBx/mmCIF format | 1gib.cif.gz | 128.6 KB | Display | PDBx/mmCIF format |
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PDB format | pdb1gib.ent.gz | 102.2 KB | Display | PDB format |
PDBx/mmJSON format | 1gib.json.gz | Tree view | PDBx/mmJSON format | |
Others | Other downloads |
-Validation report
Arichive directory | https://data.pdbj.org/pub/pdb/validation_reports/gi/1gib ftp://data.pdbj.org/pub/pdb/validation_reports/gi/1gib | HTTPS FTP |
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-Related structure data
Similar structure data |
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-Links
-Assembly
Deposited unit |
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1 |
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NMR ensembles |
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-Components
#1: Protein/peptide | Mass: 2655.264 Da / Num. of mol.: 1 Source method: isolated from a genetically manipulated source Source: (gene. exp.) Conus geographus (geography cone) / References: UniProt: P01524 |
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-Experimental details
-Experiment
Experiment | Method: SOLUTION NMR |
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-Sample preparation
Sample conditions | pH: 3.5 / Temperature: 283 K |
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Crystal grow | *PLUS Method: other / Details: NMR |
-Processing
Software |
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NMR software | Name: X-PLOR / Version: 3.1 / Developer: BRUNGER / Classification: refinement | ||||||||||||
NMR ensemble | Conformers submitted total number: 20 |