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- PDB-1etn: MOLECULAR STRUCTURE OF THE TOXIC DOMAIN OF HEAT-STABLE ENTEROTOXI... -
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Open data
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Basic information
Entry | Database: PDB / ID: 1etn | ||||||
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Title | MOLECULAR STRUCTURE OF THE TOXIC DOMAIN OF HEAT-STABLE ENTEROTOXIN PRODUCED BY A PATHOGENIC STRAIN OF ESCHERICHIA COLI | ||||||
![]() | 5-BETA-MERCAPTOPROPIONATE HEAT-STABLE ENTEROTOXIN | ||||||
![]() | ENTEROTOXIN | ||||||
Function / homology | Heat-stable enterotoxin, STa / Heat-stable enterotoxin, conserved site / Heat-stable enterotoxin ST / Heat-stable enterotoxins signature. / Intestinal infectious diseases / toxin activity / extracellular space / Heat-stable enterotoxin ST-IA/ST-P![]() | ||||||
Biological species | ![]() ![]() | ||||||
Method | ![]() | ||||||
![]() | Sato, T. / Shimonishi, Y. | ||||||
![]() | ![]() Title: Molecular structure of the toxin domain of heat-stable enterotoxin produced by a pathogenic strain of Escherichia coli. A putative binding site for a binding protein on rat intestinal epithelial cell membranes. Authors: Ozaki, H. / Sato, T. / Kubota, H. / Hata, Y. / Katsube, Y. / Shimonishi, Y. #1: ![]() Title: Structural Characteristics for Biological Activity of Heat-Stable Enterotoxin Produced by Enterotoxigenic Escherichia Coli: X-Ray Crystallography of Weakly Toxic and Nontoxic Analogs Authors: Sato, T. / Ozaki, H. / Hata, Y. / Kitagawa, Y. / Katsube, Y. / Shimonishi, Y. #2: ![]() Title: Semi-Preparative Purification and Crystallization of Synthetic Analogs of Heat-Stable Enterotoxin of Enterotoxigenic Escherichia Coli Authors: Sato, T. / Ito, H. / Takeda, Y. / Shimonishi, Y. #3: ![]() Title: Structure-Activity Relationship of Escherichia Coli Heat-Stable Enterotoxin: Role of Ala Residue at Position 14 in Toxin-Receptor Interaction Authors: Yamasaki, S. / Sato, T. / Hidaka, Y. / Ozaki, H. / Ito, H. / Hirayama, T. / Takeda, Y. / Sugimura, T. / Tai, A. / Shimonishi, Y. #4: ![]() Title: Essential Structure for Full Enterotoxigenic Activity of Heat-Stable Enterotoxin Produced by Enterotoxigenic Escherichia Coli Authors: Yoshimura, S. / Ikemura, H. / Watanabe, H. / Aimoto, H. / Shimonishi, Y. / Hara, S. / Takeda, T. / Miwatani, T. / Takeda, Y. | ||||||
History |
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Structure visualization
Structure viewer | Molecule: ![]() ![]() |
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Downloads & links
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Download
PDBx/mmCIF format | ![]() | 15.3 KB | Display | ![]() |
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PDB format | ![]() | 13.4 KB | Display | ![]() |
PDBx/mmJSON format | ![]() | Tree view | ![]() | |
Others | ![]() |
-Validation report
Summary document | ![]() | 369.6 KB | Display | ![]() |
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Full document | ![]() | 369.6 KB | Display | |
Data in XML | ![]() | 2.1 KB | Display | |
Data in CIF | ![]() | 2.3 KB | Display | |
Arichive directory | ![]() ![]() | HTTPS FTP |
-Related structure data
Similar structure data |
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Links
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Assembly
Deposited unit | ![]()
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Unit cell |
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Components
#1: Protein/peptide | Mass: 1258.555 Da / Num. of mol.: 1 Source method: isolated from a genetically manipulated source Source: (gene. exp.) ![]() ![]() |
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#2: Water | ChemComp-HOH / |
Sequence details | THE SEQUENCE IS BASED ON SEQUENCE FROM ENTEROTOXIGENIC (ESCHERICHIA COLI STRAIN 18D). THE THIRTEEN ...THE SEQUENCE IS BASED ON SEQUENCE FROM ENTEROTOXI |
-Experimental details
-Experiment
Experiment | Method: ![]() |
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Sample preparation
Crystal | Density Matthews: 1.47 Å3/Da / Density % sol: 16.52 % |
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Crystal grow | *PLUS Temperature: 24 ℃ / Method: unknown |
Components of the solutions | *PLUS Conc.: 2.5 mg/ml / Common name: enzyme |
-Data collection
Radiation | Scattering type: x-ray |
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Radiation wavelength | Relative weight: 1 |
Reflection | *PLUS Highest resolution: 0.89 Å / Num. obs: 6246 / Rmerge(I) obs: 0.024 |
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Processing
Software | Name: FMLS/VP / Classification: refinement | ||||||||||||
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Refinement | Resolution: 0.89→10.9 Å / σ(F): 3
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Refinement step | Cycle: LAST / Resolution: 0.89→10.9 Å
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Refinement | *PLUS Rfactor obs: 0.088 | ||||||||||||
Solvent computation | *PLUS | ||||||||||||
Displacement parameters | *PLUS |