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Yorodumi- PDB-1anp: SOLUTION CONFORMATION OF AN ATRIAL NATRIURETIC PEPTIDE VARIANT SE... -
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-Basic information
Entry | Database: PDB / ID: 1anp | ||||||
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Title | SOLUTION CONFORMATION OF AN ATRIAL NATRIURETIC PEPTIDE VARIANT SELECTIVE FOR THE TYPE-A RECEPTOR | ||||||
Components | ATRIAL NATRIURETIC PEPTIDE | ||||||
Keywords | HYPOTENSIVE HORMONE | ||||||
Function / homology | Function and homology information positive regulation of delayed rectifier potassium channel activity / receptor guanylyl cyclase signaling pathway / neuropeptide receptor binding / regulation of high voltage-gated calcium channel activity / positive regulation of potassium ion export across plasma membrane / cGMP biosynthetic process / regulation of atrial cardiac muscle cell membrane repolarization / Physiological factors / cardiac conduction system development / YAP1- and WWTR1 (TAZ)-stimulated gene expression ...positive regulation of delayed rectifier potassium channel activity / receptor guanylyl cyclase signaling pathway / neuropeptide receptor binding / regulation of high voltage-gated calcium channel activity / positive regulation of potassium ion export across plasma membrane / cGMP biosynthetic process / regulation of atrial cardiac muscle cell membrane repolarization / Physiological factors / cardiac conduction system development / YAP1- and WWTR1 (TAZ)-stimulated gene expression / sodium ion export across plasma membrane / negative regulation of JUN kinase activity / neuropeptide hormone activity / negative regulation of systemic arterial blood pressure / cardiac muscle hypertrophy in response to stress / hormone receptor binding / aortic valve morphogenesis / regulation of calcium ion transmembrane transport via high voltage-gated calcium channel / positive regulation of heart rate / cGMP-mediated signaling / neuropeptide signaling pathway / positive regulation of cardiac muscle contraction / response to muscle stretch / cell projection / female pregnancy / hormone activity / regulation of blood pressure / vasodilation / protein folding / perikaryon / collagen-containing extracellular matrix / Amyloid fiber formation / signaling receptor binding / protein-containing complex / extracellular space / extracellular region / cytoplasm Similarity search - Function | ||||||
Biological species | Homo sapiens (human) | ||||||
Method | SOLUTION NMR | ||||||
Authors | Fairbrother, W.J. / Mcdowell, R.S. / Cunningham, B.C. | ||||||
Citation | Journal: Biochemistry / Year: 1994 Title: Solution conformation of an atrial natriuretic peptide variant selective for the type A receptor. Authors: Fairbrother, W.J. / McDowell, R.S. / Cunningham, B.C. #1: Journal: Embo J. / Year: 1994 Title: Production of an Atrial Natriuretic Peptide Variant that is Specific for Type-A Receptors Authors: Cunningham, B.C. / Lowe, D.G. / Li, B. / Bennett, B.D. / Wells, J.A. | ||||||
History |
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-Structure visualization
Structure viewer | Molecule: MolmilJmol/JSmol |
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-Downloads & links
-Download
PDBx/mmCIF format | 1anp.cif.gz | 9.7 KB | Display | PDBx/mmCIF format |
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PDB format | pdb1anp.ent.gz | 5.8 KB | Display | PDB format |
PDBx/mmJSON format | 1anp.json.gz | Tree view | PDBx/mmJSON format | |
Others | Other downloads |
-Validation report
Arichive directory | https://data.pdbj.org/pub/pdb/validation_reports/an/1anp ftp://data.pdbj.org/pub/pdb/validation_reports/an/1anp | HTTPS FTP |
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-Related structure data
Similar structure data | Similarity search - Function & homologyF&H Search |
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-Links
-Assembly
Deposited unit |
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1 |
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NMR ensembles |
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-Components
#1: Protein/peptide | Mass: 3031.323 Da / Num. of mol.: 1 Source method: isolated from a genetically manipulated source Source: (gene. exp.) Homo sapiens (human) / Gene: POTENTIAL / References: UniProt: P01160 |
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-Experimental details
-Experiment
Experiment | Method: SOLUTION NMR |
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-Processing
NMR ensemble | Conformers submitted total number: 11 |
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