登録情報 | データベース: EMDB / ID: EMD-72400 |
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タイトル | The structure of the Plasmodium falciparum 20S proteasome |
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マップデータ | |
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試料 | - 複合体: proteasome alpha ring assembly intermediate
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キーワード | Proteasome / 20S proteasome / Plasmodium falciparum / HYDROLASE |
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機能・相同性 | 機能・相同性情報
Cross-presentation of soluble exogenous antigens (endosomes) / Proteasome assembly / Orc1 removal from chromatin / CDK-mediated phosphorylation and removal of Cdc6 / FBXL7 down-regulates AURKA during mitotic entry and in early mitosis / KEAP1-NFE2L2 pathway / UCH proteinases / Ub-specific processing proteases / Neddylation / Antigen processing: Ubiquitination & Proteasome degradation ...Cross-presentation of soluble exogenous antigens (endosomes) / Proteasome assembly / Orc1 removal from chromatin / CDK-mediated phosphorylation and removal of Cdc6 / FBXL7 down-regulates AURKA during mitotic entry and in early mitosis / KEAP1-NFE2L2 pathway / UCH proteinases / Ub-specific processing proteases / Neddylation / Antigen processing: Ubiquitination & Proteasome degradation / MAPK6/MAPK4 signaling / ABC-family proteins mediated transport / AUF1 (hnRNP D0) binds and destabilizes mRNA / Neutrophil degranulation / proteasome core complex / proteasome endopeptidase complex / proteasome core complex, beta-subunit complex / threonine-type endopeptidase activity / proteasome core complex, alpha-subunit complex / proteolysis involved in protein catabolic process / peptidase activity / ubiquitin-dependent protein catabolic process / endopeptidase activity / proteasome-mediated ubiquitin-dependent protein catabolic process / nucleus / cytosol / cytoplasm類似検索 - 分子機能 Proteasome subunit alpha 1 / Proteasome subunit beta 4 / Proteasome subunit beta 2 / Proteasome beta 3 subunit / Proteasome subunit alpha5 / Proteasome subunit alpha6 / Proteasome beta-type subunits signature. / Peptidase T1A, proteasome beta-subunit / Proteasome beta-type subunit, conserved site / Proteasome subunit A N-terminal signature ...Proteasome subunit alpha 1 / Proteasome subunit beta 4 / Proteasome subunit beta 2 / Proteasome beta 3 subunit / Proteasome subunit alpha5 / Proteasome subunit alpha6 / Proteasome beta-type subunits signature. / Peptidase T1A, proteasome beta-subunit / Proteasome beta-type subunit, conserved site / Proteasome subunit A N-terminal signature / Proteasome alpha-type subunits signature. / Proteasome alpha-subunit, N-terminal domain / Proteasome subunit A N-terminal signature Add an annotation / Proteasome B-type subunit / Proteasome beta-type subunit profile. / : / Proteasome alpha-type subunit / Proteasome alpha-type subunit profile. / Proteasome subunit / Proteasome, subunit alpha/beta / Nucleophile aminohydrolases, N-terminal類似検索 - ドメイン・相同性 Proteasome subunit alpha type / Proteasome subunit beta / Proteasome endopeptidase complex / Proteasome subunit beta / Proteasome subunit alpha type-2 / Proteasome subunit alpha type-3, putative / Proteasome subunit beta / Proteasome subunit beta / Proteasome subunit alpha type-6, putative / Proteasome subunit alpha type ...Proteasome subunit alpha type / Proteasome subunit beta / Proteasome endopeptidase complex / Proteasome subunit beta / Proteasome subunit alpha type-2 / Proteasome subunit alpha type-3, putative / Proteasome subunit beta / Proteasome subunit beta / Proteasome subunit alpha type-6, putative / Proteasome subunit alpha type / Proteasome subunit alpha type / Proteasome subunit beta / Proteasome subunit alpha type-1, putative / Proteasome subunit beta類似検索 - 構成要素 |
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生物種 |  Plasmodium falciparum Dd2 (マラリア病原虫) |
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手法 | 単粒子再構成法 / クライオ電子顕微鏡法 / 解像度: 3.1 Å |
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データ登録者 | Zhang H / Zhao J / Fajtova P / O'Donoghue AJ |
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資金援助 | 米国, European Union, チェコ, 12件 Organization | Grant number | 国 |
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Department of Defense (DOD, United States) | W81XWH2210520 | 米国 | National Institutes of Health/National Institute Of Allergy and Infectious Diseases (NIH/NIAID) | R01 AI158612 | 米国 | National Institutes of Health/National Institute Of Allergy and Infectious Diseases (NIH/NIAID) | R21 AI146387 | 米国 | National Institutes of Health/National Institute Of Allergy and Infectious Diseases (NIH/NIAID) | R21 AI133393 | 米国 | National Institutes of Health/National Institute Of Allergy and Infectious Diseases (NIH/NIAID) | R21 AI171824 | 米国 | National Institutes of Health/National Institute of General Medical Sciences (NIH/NIGMS) | R35 GM147487 | 米国 | National Institutes of Health/Office of the Director | S10 OD026926 | 米国 | National Institutes of Health/National Cancer Institute (NIH/NCI) | P30 CA030199 | 米国 | H2020 Marie Curie Actions of the European Commission | 846688 | European Union | European Union (EU) | LX22NPO5103 | European Union | Ministry of Education, Youth and Sports of the Czech Republic | LM2023042 | チェコ | European Regional Development Fund | CZ.02.01.01/00/23_015/0008175 | European Union |
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引用 | ジャーナル: To Be Published タイトル: Incorrectly assembled half-Pf20S 著者: Zhang H / Zhao J / Fajtova P / O'Donoghue AJ |
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履歴 | 登録 | 2025年8月29日 | - |
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ヘッダ(付随情報) 公開 | 2025年10月8日 | - |
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マップ公開 | 2025年10月8日 | - |
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更新 | 2025年10月8日 | - |
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現状 | 2025年10月8日 | 処理サイト: RCSB / 状態: 公開 |
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