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- EMDB-6693: the resting state of yeast proteasome -

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基本情報

登録情報
データベース: EMDB / ID: EMD-6693
タイトルthe resting state of yeast proteasome
マップデータ
試料
  • 複合体: The yeast resting state proteasome
    • タンパク質・ペプチド: x 33種
キーワードresting state yeast proteasome nucleotide occupied / HYDROLASE
機能・相同性
機能・相同性情報


SAGA complex localization to transcription regulatory region / Metalloprotease DUBs / proteasome regulatory particle assembly / proteasome storage granule assembly / transcription export complex 2 / protein deneddylation / peroxisome fission / maintenance of DNA trinucleotide repeats / filamentous growth / COP9 signalosome ...SAGA complex localization to transcription regulatory region / Metalloprotease DUBs / proteasome regulatory particle assembly / proteasome storage granule assembly / transcription export complex 2 / protein deneddylation / peroxisome fission / maintenance of DNA trinucleotide repeats / filamentous growth / COP9 signalosome / protein-containing complex localization / proteasome regulatory particle / proteasome-activating activity / mitochondrial fission / proteasome regulatory particle, lid subcomplex / proteasome regulatory particle, base subcomplex / metal-dependent deubiquitinase activity / K48-linked polyubiquitin modification-dependent protein binding / proteasome core complex assembly / nuclear outer membrane-endoplasmic reticulum membrane network / Proteasome assembly / Cross-presentation of soluble exogenous antigens (endosomes) / TNFR2 non-canonical NF-kB pathway / proteasomal ubiquitin-independent protein catabolic process / Ubiquitin Mediated Degradation of Phosphorylated Cdc25A / Regulation of PTEN stability and activity / nonfunctional rRNA decay / CDK-mediated phosphorylation and removal of Cdc6 / FBXL7 down-regulates AURKA during mitotic entry and in early mitosis / peptide catabolic process / KEAP1-NFE2L2 pathway / Neddylation / proteasome binding / Orc1 removal from chromatin / MAPK6/MAPK4 signaling / regulation of protein catabolic process / proteasome storage granule / Antigen processing: Ubiquitination & Proteasome degradation / polyubiquitin modification-dependent protein binding / positive regulation of RNA polymerase II transcription preinitiation complex assembly / protein deubiquitination / endopeptidase activator activity / Ub-specific processing proteases / proteasome endopeptidase complex / proteasome core complex, beta-subunit complex / proteasome assembly / threonine-type endopeptidase activity / proteasome core complex, alpha-subunit complex / mRNA export from nucleus / enzyme regulator activity / ERAD pathway / Neutrophil degranulation / protein folding chaperone / proteasome complex / ubiquitin binding / nucleotide-excision repair / positive regulation of transcription elongation by RNA polymerase II / double-strand break repair via homologous recombination / positive regulation of protein catabolic process / metallopeptidase activity / peroxisome / ubiquitin-dependent protein catabolic process / protein-macromolecule adaptor activity / endopeptidase activity / molecular adaptor activity / proteasome-mediated ubiquitin-dependent protein catabolic process / ubiquitinyl hydrolase 1 / cysteine-type deubiquitinase activity / regulation of cell cycle / chromatin remodeling / protein domain specific binding / mRNA binding / ubiquitin protein ligase binding / endoplasmic reticulum membrane / structural molecule activity / endoplasmic reticulum / positive regulation of transcription by RNA polymerase II / ATP hydrolysis activity / mitochondrion / ATP binding / metal ion binding / identical protein binding / nucleus / cytosol / cytoplasm
類似検索 - 分子機能
Rpn9, C-terminal helix / Rpn9 C-terminal helix / Proteasomal ubiquitin receptor Rpn13/ADRM1 / Proteasomal ubiquitin receptor Rpn13/ADRM1, Pru domain superfamily / Rpn13/ADRM1, Pru domain / Proteasome complex subunit Rpn13, Pru domain / Pru (pleckstrin-like receptor for ubiquitin) domain profile. / : / 26S proteasome regulatory subunit RPN7/PSMD6 C-terminal helix / 26S proteasome non-ATPase regulatory subunit Rpn12 ...Rpn9, C-terminal helix / Rpn9 C-terminal helix / Proteasomal ubiquitin receptor Rpn13/ADRM1 / Proteasomal ubiquitin receptor Rpn13/ADRM1, Pru domain superfamily / Rpn13/ADRM1, Pru domain / Proteasome complex subunit Rpn13, Pru domain / Pru (pleckstrin-like receptor for ubiquitin) domain profile. / : / 26S proteasome regulatory subunit RPN7/PSMD6 C-terminal helix / 26S proteasome non-ATPase regulatory subunit Rpn12 / 26S proteasome regulatory subunit, C-terminal / Proteasome regulatory subunit C-terminal / 26S proteasome regulatory subunit RPN5, C-terminal domain / : / 26S proteasome regulatory subunit RPN5 C-terminal domain / PSD13 N-terminal repeats / 26S proteasome regulatory subunit Rpn6, N-terminal / 6S proteasome subunit Rpn6, C-terminal helix domain / 26S proteasome regulatory subunit RPN6 N-terminal domain / 26S proteasome subunit RPN6 C-terminal helix domain / 26S Proteasome non-ATPase regulatory subunit 13 / : / 26S proteasome subunit RPN2, N-terminal domain / 26S proteasome regulatory complex, non-ATPase subcomplex, Rpn2/Psmd1 subunit / 26S proteasome regulatory subunit RPN2, C-terminal / 26S proteasome regulatory subunit RPN2 C-terminal domain / : / 26S proteasome regulatory subunit RPN11 C-terminal domain / DSS1/SEM1 / Proteasome subunit Rpn10 / 26S Proteasome non-ATPase regulatory subunit 7/8 / DSS1/SEM1 family / DSS1_SEM1 / 26S proteasome regulatory complex, non-ATPase subcomplex, Rpn1 subunit / RPN1, N-terminal / 26S proteasome non-ATPase regulatory subunit RPN1, C-terminal / RPN1 N-terminal domain / 26S proteasome non-ATPase regulatory subunit RPN1 C-terminal / : / 26S proteasome regulatory subunit 7, OB domain / : / : / : / PSMD12/CSN4, N-terminal / 26S proteasome regulatory subunit Rpn7/COP9 signalosome complex subunit 1 / 26S proteasome regulatory subunit Rpn7, N-terminal / 26S proteasome subunit RPN7 / 26S Proteasome non-ATPase regulatory subunit 12/COP9 signalosome complex subunit 4 / Proteasome/cyclosome repeat / Proteasome/cyclosome repeat / PCI/PINT associated module / : / von Willebrand factor type A domain / Proteasomal ATPase OB C-terminal domain / Proteasomal ATPase OB C-terminal domain / CSN8/PSMD8/EIF3K / CSN8/PSMD8/EIF3K family / Rpn11/EIF3F, C-terminal / Maintenance of mitochondrial structure and function / HEAT repeats / : / motif in proteasome subunits, Int-6, Nip-1 and TRIP-15 / PCI domain / Proteasome component (PCI) domain / PCI domain profile. / Ubiquitin interacting motif / Ubiquitin-interacting motif (UIM) domain profile. / JAB1/Mov34/MPN/PAD-1 ubiquitin protease / Proteasome beta subunit, C-terminal / Proteasome beta subunits C terminal / Proteasome subunit beta 4 / Proteasome subunit beta 2 / Proteasome beta 3 subunit / Proteasome subunit alpha6 / Proteasome subunit alpha5 / Proteasome beta-type subunits signature. / Peptidase T1A, proteasome beta-subunit / Proteasome beta-type subunit, conserved site / Proteasome subunit A N-terminal signature / Proteasome alpha-type subunits signature. / Proteasome alpha-subunit, N-terminal domain / Proteasome subunit A N-terminal signature Add an annotation / VWFA domain profile. / Proteasome B-type subunit / Proteasome beta-type subunit profile. / : / Proteasome alpha-type subunit / Proteasome alpha-type subunit profile. / Proteasome subunit / Proteasome, subunit alpha/beta / von Willebrand factor, type A / AAA ATPase, AAA+ lid domain / AAA+ lid domain / TPR repeat region circular profile. / JAB/MPN domain / JAB1/MPN/MOV34 metalloenzyme domain / ATPase, AAA-type, conserved site / AAA-protein family signature. / TPR repeat profile. / MPN domain
類似検索 - ドメイン・相同性
26S proteasome regulatory subunit RPN13 / 26S proteasome complex subunit SEM1 / Probable proteasome subunit alpha type-7 / Proteasome subunit alpha type-1 / Proteasome subunit beta type-4 / Proteasome subunit alpha type-3 / Proteasome subunit alpha type-2 / Proteasome subunit beta type-6 / Proteasome subunit beta type-2 / Proteasome subunit beta type-3 ...26S proteasome regulatory subunit RPN13 / 26S proteasome complex subunit SEM1 / Probable proteasome subunit alpha type-7 / Proteasome subunit alpha type-1 / Proteasome subunit beta type-4 / Proteasome subunit alpha type-3 / Proteasome subunit alpha type-2 / Proteasome subunit beta type-6 / Proteasome subunit beta type-2 / Proteasome subunit beta type-3 / Proteasome subunit beta type-5 / Proteasome subunit beta type-7 / Proteasome subunit alpha type-5 / 26S proteasome regulatory subunit RPN12 / 26S proteasome regulatory subunit RPN2 / 26S proteasome regulatory subunit 6A / 26S proteasome regulatory subunit 6B homolog / 26S proteasome regulatory subunit 7 homolog / Proteasome subunit beta type-1 / 26S proteasome regulatory subunit RPN1 / 26S proteasome regulatory subunit RPN10 / 26S proteasome regulatory subunit RPN3 / Proteasome subunit alpha type-6 / Proteasome subunit alpha type-4 / 26S proteasome regulatory subunit 4 homolog / Ubiquitin carboxyl-terminal hydrolase RPN11 / 26S proteasome subunit RPT4 / 26S proteasome regulatory subunit 8 homolog / 26S proteasome regulatory subunit RPN9 / 26S proteasome regulatory subunit RPN7 / 26S proteasome regulatory subunit RPN8 / 26S proteasome regulatory subunit RPN5 / 26S proteasome regulatory subunit RPN6
類似検索 - 構成要素
生物種Saccharomyces cerevisiae (パン酵母) / Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (パン酵母)
手法単粒子再構成法 / クライオ電子顕微鏡法 / 解像度: 6.3 Å
データ登録者Ding Z / Cong Y
資金援助 中国, 6件
OrganizationGrant number国
CASXDB08030201 中国
National Natural Science Foundation of China31270771 中国
National Natural Science Foundation of China31222016 中国
National Basic Research Program of China2013CB910401 中国
CASKFJ-EW-STS-098 中国
CASCAS-SSRC-YH-2015-01 中国
引用ジャーナル: Cell Res / 年: 2017
タイトル: High-resolution cryo-EM structure of the proteasome in complex with ADP-AlFx.
著者: Zhanyu Ding / Zhenglin Fu / Cong Xu / Yifan Wang / Yanxing Wang / Junrui Li / Liangliang Kong / Jinhuan Chen / Na Li / Rongguang Zhang / Yao Cong /
要旨: The 26S proteasome is an ATP-dependent dynamic 2.5 MDa protease that regulates numerous essential cellular functions through degradation of ubiquitinated substrates. Here we present a near-atomic- ...The 26S proteasome is an ATP-dependent dynamic 2.5 MDa protease that regulates numerous essential cellular functions through degradation of ubiquitinated substrates. Here we present a near-atomic-resolution cryo-EM map of the S. cerevisiae 26S proteasome in complex with ADP-AlFx. Our biochemical and structural data reveal that the proteasome-ADP-AlFx is in an activated state, displaying a distinct conformational configuration especially in the AAA-ATPase motor region. Noteworthy, this map demonstrates an asymmetric nucleotide binding pattern with four consecutive AAA-ATPase subunits bound with nucleotide. The remaining two subunits, Rpt2 and Rpt6, with empty or only partially occupied nucleotide pocket exhibit pronounced conformational changes in the AAA-ATPase ring, which may represent a collective result of allosteric cooperativity of all the AAA-ATPase subunits responding to ATP hydrolysis. This collective motion of Rpt2 and Rpt6 results in an elevation of their pore loops, which could play an important role in substrate processing of proteasome. Our data also imply that the nucleotide occupancy pattern could be related to the activation status of the complex. Moreover, the HbYX tail insertion may not be sufficient to maintain the gate opening of 20S core particle. Our results provide new insights into the mechanisms of nucleotide-driven allosteric cooperativity of the complex and of the substrate processing by the proteasome.
履歴
登録2016年12月25日-
ヘッダ(付随情報) 公開2017年3月22日-
マップ公開2017年3月22日-
更新2024年10月30日-
現状2024年10月30日処理サイト: PDBj / 状態: 公開

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構造の表示

ムービー
  • 表面図（断面を密度値に従い着色）
  • 表面レベル: 0.755
  • UCSF Chimeraによる作画
  • ダウンロード
  • 表面図（半径に従い着色）
  • 表面レベル: 0.755
  • UCSF Chimeraによる作画
  • ダウンロード
  • あてはめたモデルとの重ね合わせ
  • 原子モデル: PDB-5wvi
  • 表面レベル: 0.755
  • UCSF Chimeraによる作画
  • ダウンロード
ムービービューア
構造ビューアEMマップ:
SurfViewMolmilJmol/JSmol
添付画像

emd_6693.png

ダウンロードとリンク

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マップ

ファイルダウンロード / ファイル: emd_6693.map.gz / 形式: CCP4 / 大きさ: 178 MB / タイプ: IMAGE STORED AS FLOATING POINT NUMBER (4 BYTES)
投影像・断面図

画像のコントロール

大きさ
明度
コントラスト
その他
軸Z (Sec.)Y (Row.)X (Col.)
1.32 Å/pix.
x 360 pix.
= 474.48 Å		1.32 Å/pix.
x 360 pix.
= 474.48 Å		1.32 Å/pix.
x 360 pix.
= 474.48 Å

表面

投影像

断面 (1/3)

断面 (1/2)

断面 (2/3)

画像は Spider により作成

ボクセルのサイズX=Y=Z: 1.318 Å
密度

ヒストグラム

ヒストグラム (対数)
表面レベル登録者による: 0.755 / ムービー #1: 0.755
最小 - 最大-1.142053 - 2.2366624
平均 (標準偏差)0.011550687 (±0.123066016)
対称性空間群: 1
詳細

EMDB XML:

マップ形状
Axis orderXYZ
Origin000
サイズ360360360
Spacing360360360
セルA=B=C: 474.47998 Å
α=β=γ: 90.0 °

CCP4マップ ヘッダ情報:

modeImage stored as Reals
Å/pix. X/Y/Z1.3181.3181.318
M x/y/z360360360
origin x/y/z0.0000.0000.000
length x/y/z474.480474.480474.480
α/β/γ90.00090.00090.000
MAP C/R/S123
start NC/NR/NS000
NC/NR/NS360360360
D min/max/mean-1.1422.2370.012

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添付データ

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試料の構成要素

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全体 : The yeast resting state proteasome

全体名称: The yeast resting state proteasome
要素
  • 複合体: The yeast resting state proteasome
    • タンパク質・ペプチド: 26S protease regulatory subunit 4 homolog
    • タンパク質・ペプチド: 26S protease regulatory subunit 6B homolog
    • タンパク質・ペプチド: Proteasome subunit beta type-2
    • タンパク質・ペプチド: Proteasome subunit alpha type-1
    • タンパク質・ペプチド: Proteasome subunit beta type-3
    • タンパク質・ペプチド: Probable proteasome subunit alpha type-7
    • タンパク質・ペプチド: Proteasome subunit alpha type-6
    • タンパク質・ペプチド: Proteasome subunit alpha type-5
    • タンパク質・ペプチド: Proteasome subunit alpha type-4
    • タンパク質・ペプチド: 26S proteasome complex subunit SEM1
    • タンパク質・ペプチド: 26S proteasome regulatory subunit RPN2
    • タンパク質・ペプチド: 26S proteasome regulatory subunit RPN3
    • タンパク質・ペプチド: 26S proteasome regulatory subunit RPN12
    • タンパク質・ペプチド: 26S proteasome regulatory subunit RPN7
    • タンパク質・ペプチド: 26S proteasome regulatory subunit RPN6
    • タンパク質・ペプチド: 26S protease regulatory subunit 8 homolog
    • タンパク質・ペプチド: 26S protease subunit RPT4
    • タンパク質・ペプチド: 26S protease regulatory subunit 6A
    • タンパク質・ペプチド: 26S proteasome regulatory subunit RPN8
    • タンパク質・ペプチド: 26S proteasome regulatory subunit RPN10
    • タンパク質・ペプチド: 26S proteasome regulatory subunit RPN9
    • タンパク質・ペプチド: 26S proteasome regulatory subunit RPN5
    • タンパク質・ペプチド: 26S protease regulatory subunit 7 homolog
    • タンパク質・ペプチド: Proteasome subunit alpha type-3
    • タンパク質・ペプチド: Proteasome subunit alpha type-2
    • タンパク質・ペプチド: Proteasome subunit beta type-1
    • タンパク質・ペプチド: Proteasome subunit beta type-4
    • タンパク質・ペプチド: Proteasome subunit beta type-5
    • タンパク質・ペプチド: Proteasome subunit beta type-6
    • タンパク質・ペプチド: Proteasome subunit beta type-7
    • タンパク質・ペプチド: 26S proteasome regulatory subunit RPN13
    • タンパク質・ペプチド: 26S proteasome regulatory subunit RPN1
    • タンパク質・ペプチド: Ubiquitin carboxyl-terminal hydrolase RPN11

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超分子 #1: The yeast resting state proteasome

超分子名称: The yeast resting state proteasome / タイプ: complex / ID: 1 / 親要素: 0 / 含まれる分子: all
由来(天然)生物種: Saccharomyces cerevisiae (パン酵母)
分子量理論値: 1.6 MDa

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分子 #1: 26S protease regulatory subunit 4 homolog

分子名称: 26S protease regulatory subunit 4 homolog / タイプ: protein_or_peptide / ID: 1 / コピー数: 1 / 光学異性体: LEVO
由来(天然)生物種: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (パン酵母)
株: ATCC 204508 / S288c
分子量理論値: 48.89816 KDa
配列文字列: MGQGVSSGQD KKKKKGSNQK PKYEPPVQSK FGRKKRKGGP ATAEKLPNIY PSTRCKLKLL RMERIKDHLL LEEEFVSNSE ILKPFEKKQ EEEKKQLEEI RGNPLSIGTL EEIIDDDHAI VTSPTMPDYY VSILSFVDKE LLEPGCSVLL HHKTMSIVGV L QDDADPMV ...文字列:
MGQGVSSGQD KKKKKGSNQK PKYEPPVQSK FGRKKRKGGP ATAEKLPNIY PSTRCKLKLL RMERIKDHLL LEEEFVSNSE ILKPFEKKQ EEEKKQLEEI RGNPLSIGTL EEIIDDDHAI VTSPTMPDYY VSILSFVDKE LLEPGCSVLL HHKTMSIVGV L QDDADPMV SVMKMDKSPT ESYSDIGGLE SQIQEIKESV ELPLTHPELY EEMGIKPPKG VILYGAPGTG KTLLAKAVAN QT SATFLRI VGSELIQKYL GDGPRLCRQI FKVAGENAPS IVFIDEIDAI GTKRYDSNSG GEREIQRTML ELLNQLDGFD DRG DVKVIM ATNKIETLDP ALIRPGRIDR KILFENPDLS TKKKILGIHT SKMNLSEDVN LETLVTTKDD LSGADIQAMC TEAG LLALR ERRMQVTAED FKQAKERVMK NKVEENLEGL YL

UniProtKB: 26S proteasome regulatory subunit 4 homolog

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分子 #2: 26S protease regulatory subunit 6B homolog

分子名称: 26S protease regulatory subunit 6B homolog / タイプ: protein_or_peptide / ID: 2 / コピー数: 1 / 光学異性体: LEVO
由来(天然)生物種: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (パン酵母)
株: ATCC 204508 / S288c
分子量理論値: 47.953676 KDa
配列文字列: MEELGIVTPV EKAVEEKPAV KSYASLLAQL NGTVNNNSAL SNVNSDIYFK LKKLEKEYEL LTLQEDYIKD EQRHLKRELK RAQEEVKRI QSVPLVIGQF LEPIDQNTGI VSSTTGMSYV VRILSTLDRE LLKPSMSVAL HRHSNALVDI LPPDSDSSIS V MGENEKPD ...文字列:
MEELGIVTPV EKAVEEKPAV KSYASLLAQL NGTVNNNSAL SNVNSDIYFK LKKLEKEYEL LTLQEDYIKD EQRHLKRELK RAQEEVKRI QSVPLVIGQF LEPIDQNTGI VSSTTGMSYV VRILSTLDRE LLKPSMSVAL HRHSNALVDI LPPDSDSSIS V MGENEKPD VTYADVGGLD MQKQEIREAV ELPLVQADLY EQIGIDPPRG VLLYGPPGTG KTMLVKAVAN STKAAFIRVN GS EFVHKYL GEGPRMVRDV FRLARENAPS IIFIDEVDSI ATKRFDAQTG SDREVQRILI ELLTQMDGFD QSTNVKVIMA TNR ADTLDP ALLRPGRLDR KIEFPSLRDR RERRLIFGTI ASKMSLAPEA DLDSLIIRND SLSGAVIAAI MQEAGLRAVR KNRY VILQS DLEEAYATQV KTDNTVDKFD FYK

UniProtKB: 26S proteasome regulatory subunit 6B homolog

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分子 #3: Proteasome subunit beta type-2

分子名称: Proteasome subunit beta type-2 / タイプ: protein_or_peptide / ID: 3 / コピー数: 2 / 光学異性体: LEVO / EC番号: proteasome endopeptidase complex
由来(天然)生物種: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (パン酵母)
株: ATCC 204508 / S288c
分子量理論値: 28.299889 KDa
配列文字列: MAGLSFDNYQ RNNFLAENSH TQPKATSTGT TIVGVKFNNG VVIAADTRST QGPIVADKNC AKLHRISPKI WCAGAGTAAD TEAVTQLIG SNIELHSLYT SREPRVVSAL QMLKQHLFKY QGHIGAYLIV AGVDPTGSHL FSIHAHGSTD VGYYLSLGSG S LAAMAVLE ...文字列:
MAGLSFDNYQ RNNFLAENSH TQPKATSTGT TIVGVKFNNG VVIAADTRST QGPIVADKNC AKLHRISPKI WCAGAGTAAD TEAVTQLIG SNIELHSLYT SREPRVVSAL QMLKQHLFKY QGHIGAYLIV AGVDPTGSHL FSIHAHGSTD VGYYLSLGSG S LAAMAVLE SHWKQDLTKE EAIKLASDAI QAGIWNDLGS GSNVDVCVME IGKDAEYLRN YLTPNVREEK QKSYKFPRGT TA VLKESIV NICDIQEEQV DITA

UniProtKB: Proteasome subunit beta type-2

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分子 #4: Proteasome subunit alpha type-1

分子名称: Proteasome subunit alpha type-1 / タイプ: protein_or_peptide / ID: 4 / コピー数: 2 / 光学異性体: LEVO / EC番号: proteasome endopeptidase complex
由来(天然)生物種: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (パン酵母)
株: ATCC 204508 / S288c
分子量理論値: 28.03383 KDa
配列文字列: MSGAAAASAA GYDRHITIFS PEGRLYQVEY AFKATNQTNI NSLAVRGKDC TVVISQKKVP DKLLDPTTVS YIFCISRTIG MVVNGPIPD ARNAALRAKA EAAEFRYKYG YDMPCDVLAK RMANLSQIYT QRAYMRPLGV ILTFVSVDEE LGPSIYKTDP A GYYVGYKA ...文字列:
MSGAAAASAA GYDRHITIFS PEGRLYQVEY AFKATNQTNI NSLAVRGKDC TVVISQKKVP DKLLDPTTVS YIFCISRTIG MVVNGPIPD ARNAALRAKA EAAEFRYKYG YDMPCDVLAK RMANLSQIYT QRAYMRPLGV ILTFVSVDEE LGPSIYKTDP A GYYVGYKA TATGPKQQEI TTNLENHFKK SKIDHINEES WEKVVEFAIT HMIDALGTEF SKNDLEVGVA TKDKFFTLSA EN IEERLVA IAEQD

UniProtKB: Proteasome subunit alpha type-1

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分子 #5: Proteasome subunit beta type-3

分子名称: Proteasome subunit beta type-3 / タイプ: protein_or_peptide / ID: 5 / コピー数: 2 / 光学異性体: LEVO / EC番号: proteasome endopeptidase complex
由来(天然)生物種: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (パン酵母)
株: ATCC 204508 / S288c
分子量理論値: 22.627842 KDa
配列文字列: MSDPSSINGG IVVAMTGKDC VAIACDLRLG SQSLGVSNKF EKIFHYGHVF LGITGLATDV TTLNEMFRYK TNLYKLKEER AIEPETFTQ LVSSSLYERR FGPYFVGPVV AGINSKSGKP FIAGFDLIGC IDEAKDFIVS GTASDQLFGM CESLYEPNLE P EDLFETIS ...文字列:
MSDPSSINGG IVVAMTGKDC VAIACDLRLG SQSLGVSNKF EKIFHYGHVF LGITGLATDV TTLNEMFRYK TNLYKLKEER AIEPETFTQ LVSSSLYERR FGPYFVGPVV AGINSKSGKP FIAGFDLIGC IDEAKDFIVS GTASDQLFGM CESLYEPNLE P EDLFETIS QALLNAADRD ALSGWGAVVY IIKKDEVVKR YLKMRQD

UniProtKB: Proteasome subunit beta type-3

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分子 #6: Probable proteasome subunit alpha type-7

分子名称: Probable proteasome subunit alpha type-7 / タイプ: protein_or_peptide / ID: 6 / コピー数: 2 / 光学異性体: LEVO / EC番号: proteasome endopeptidase complex
由来(天然)生物種: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (パン酵母)
株: ATCC 204508 / S288c
分子量理論値: 31.575068 KDa
配列文字列: MTSIGTGYDL SNSVFSPDGR NFQVEYAVKA VENGTTSIGI KCNDGVVFAV EKLITSKLLV PQKNVKIQVV DRHIGCVYSG LIPDGRHLV NRGREEAASF KKLYKTPIPI PAFADRLGQY VQAHTLYNSV RPFGVSTIFG GVDKNGAHLY MLEPSGSYWG Y KGAATGKG ...文字列:
MTSIGTGYDL SNSVFSPDGR NFQVEYAVKA VENGTTSIGI KCNDGVVFAV EKLITSKLLV PQKNVKIQVV DRHIGCVYSG LIPDGRHLV NRGREEAASF KKLYKTPIPI PAFADRLGQY VQAHTLYNSV RPFGVSTIFG GVDKNGAHLY MLEPSGSYWG Y KGAATGKG RQSAKAELEK LVDHHPEGLS AREAVKQAAK IIYLAHEDNK EKDFELEISW CSLSETNGLH KFVKGDLLQE AI DFAQKEI NGDDDEDEDD SDNVMSSDDE NAPVATNANA TTDQEGDIHL E

UniProtKB: Probable proteasome subunit alpha type-7

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分子 #7: Proteasome subunit alpha type-6

分子名称: Proteasome subunit alpha type-6 / タイプ: protein_or_peptide / ID: 7 / コピー数: 2 / 光学異性体: LEVO / EC番号: proteasome endopeptidase complex
由来(天然)生物種: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (パン酵母)
株: ATCC 204508 / S288c
分子量理論値: 25.634 KDa
配列文字列: MFRNNYDGDT VTFSPTGRLF QVEYALEAIK QGSVTVGLRS NTHAVLVALK RNADELSSYQ KKIIKCDEHM GLSLAGLAPD ARVLSNYLR QQCNYSSLVF NRKLAVERAG HLLCDKAQKN TQSYGGRPYG VGLLIIGYDK SGAHLLEFQP SGNVTELYGT A IGARSQGA ...文字列:
MFRNNYDGDT VTFSPTGRLF QVEYALEAIK QGSVTVGLRS NTHAVLVALK RNADELSSYQ KKIIKCDEHM GLSLAGLAPD ARVLSNYLR QQCNYSSLVF NRKLAVERAG HLLCDKAQKN TQSYGGRPYG VGLLIIGYDK SGAHLLEFQP SGNVTELYGT A IGARSQGA KTYLERTLDT FIKIDGNPDE LIKAGVEAIS QSLRDESLTV DNLSIAIVGK DTPFTIYDGE AVAKYI

UniProtKB: Proteasome subunit alpha type-6

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分子 #8: Proteasome subunit alpha type-5

分子名称: Proteasome subunit alpha type-5 / タイプ: protein_or_peptide / ID: 8 / コピー数: 2 / 光学異性体: LEVO / EC番号: proteasome endopeptidase complex
由来(天然)生物種: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (パン酵母)
株: ATCC 204508 / S288c
分子量理論値: 28.649086 KDa
配列文字列: MFLTRSEYDR GVSTFSPEGR LFQVEYSLEA IKLGSTAIGI ATKEGVVLGV EKRATSPLLE SDSIEKIVEI DRHIGCAMSG LTADARSMI EHARTAAVTH NLYYDEDINV ESLTQSVCDL ALRFGEGASG EERLMSRPFG VALLIAGHDA DDGYQLFHAE P SGTFYRYN ...文字列:
MFLTRSEYDR GVSTFSPEGR LFQVEYSLEA IKLGSTAIGI ATKEGVVLGV EKRATSPLLE SDSIEKIVEI DRHIGCAMSG LTADARSMI EHARTAAVTH NLYYDEDINV ESLTQSVCDL ALRFGEGASG EERLMSRPFG VALLIAGHDA DDGYQLFHAE P SGTFYRYN AKAIGSGSEG AQAELLNEWH SSLTLKEAEL LVLKILKQVM EEKLDENNAQ LSCITKQDGF KIYDNEKTAE LI KELKEKE AAESPEEADV EMS

UniProtKB: Proteasome subunit alpha type-5

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分子 #9: Proteasome subunit alpha type-4

分子名称: Proteasome subunit alpha type-4 / タイプ: protein_or_peptide / ID: 9 / コピー数: 2 / 光学異性体: LEVO / EC番号: proteasome endopeptidase complex
由来(天然)生物種: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (パン酵母)
株: ATCC 204508 / S288c
分子量理論値: 28.478111 KDa
配列文字列: MSGYDRALSI FSPDGHIFQV EYALEAVKRG TCAVGVKGKN CVVLGCERRS TLKLQDTRIT PSKVSKIDSH VVLSFSGLNA DSRILIEKA RVEAQSHRLT LEDPVTVEYL TRYVAGVQQR YTQSGGVRPF GVSTLIAGFD PRDDEPKLYQ TEPSGIYSSW S AQTIGRNS ...文字列:
MSGYDRALSI FSPDGHIFQV EYALEAVKRG TCAVGVKGKN CVVLGCERRS TLKLQDTRIT PSKVSKIDSH VVLSFSGLNA DSRILIEKA RVEAQSHRLT LEDPVTVEYL TRYVAGVQQR YTQSGGVRPF GVSTLIAGFD PRDDEPKLYQ TEPSGIYSSW S AQTIGRNS KTVREFLEKN YDRKEPPATV EECVKLTVRS LLEVVQTGAK NIEITVVKPD SDIVALSSEE INQYVTQIEQ EK QEQQEQD KKKKSNH

UniProtKB: Proteasome subunit alpha type-4

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分子 #10: 26S proteasome complex subunit SEM1

分子名称: 26S proteasome complex subunit SEM1 / タイプ: protein_or_peptide / ID: 10 / コピー数: 1 / 光学異性体: LEVO
由来(天然)生物種: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (パン酵母)
株: ATCC 204508 / S288c
分子量理論値: 10.397102 KDa
配列文字列:
MSTDVAAAQA QSKIDLTKKK NEEINKKSLE EDDEFEDFPI DTWANGETIK SNAVTQTNIW EENWDDVEVD DDFTNELKAE LDRYKRENQ

UniProtKB: 26S proteasome complex subunit SEM1

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分子 #11: 26S proteasome regulatory subunit RPN2

分子名称: 26S proteasome regulatory subunit RPN2 / タイプ: protein_or_peptide / ID: 11 / コピー数: 1 / 光学異性体: LEVO
由来(天然)生物種: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (パン酵母)
株: ATCC 204508 / S288c
分子量理論値: 104.351883 KDa
配列文字列: MSLTTAAPLL ALLRENQDSV KTYALESINN VVDQLWSEIS NELPDIEALY DDDTFSDREM AALIASKVYY NLGEYESAVK YALAAKDRF DIDEKSQFVE TIVSKSIEMY VQEASKQYTK DEQFYTKDII DPKLTSIFER MIEKCLKASE LKLALGIALE G YRLDIIES ...文字列:
MSLTTAAPLL ALLRENQDSV KTYALESINN VVDQLWSEIS NELPDIEALY DDDTFSDREM AALIASKVYY NLGEYESAVK YALAAKDRF DIDEKSQFVE TIVSKSIEMY VQEASKQYTK DEQFYTKDII DPKLTSIFER MIEKCLKASE LKLALGIALE G YRLDIIES ALKSKLDQDS TSENVKIINY LLTLAITTVT NSKFRSSILR KSFDFLMNMP NCDYLTLNKV VVNLNDAGLA LQ LFKKLKE ENDEGLSAQI AFDLVSSASQ QLLEILVTEL TAQGYDPALL NILSGLPTCD YYNTFLLNNK NIDIGLLNKS KSS LDGKFS LFHTAVSVAN GFMHAGTTDN SFIKANLPWL GKAQNWAKFT ATASLGVIHK GNLLEGKKVM APYLPGSRAS SRFI KGGSL YGLGLIYAGF GRDTTDYLKN IIVENSGTSG DEDVDVLLHG ASLGIGLAAM GSANIEVYEA LKEVLYNDSA TSGEA AALG MGLCMLGTGK PEAIHDMFTY SQETQHGNIT RGLAVGLALI NYGRQELADD LITKMLASDE SLLRYGGAFT IALAYA GTG NNSAVKRLLH VAVSDSNDDV RRAAVIALGF VLLRDYTTVP RIVQLLSKSH NAHVRCGTAF ALGIACAGKG LQSAIDV LD PLTKDPVDFV RQAAMIALSM ILIQQTEKLN PQVADINKNF LSVITNKHQE GLAKFGACVA QGIMNAGGRN VTIQLENA D TGTLDTKSVV GLVMFSQFWY WFPLAHFLSL SFTPTTVIGI RGSDQAIPKF QMNCYAKEDA FSYPRMYEEA SGKEVEKVA TAVLSTTARA KARAKKTKKE KGPNEEEKKK EHEEKEKERE TNKKGIKETK ENDEEFYKNK YSSKPYKVDN MTRILPQQSR YISFIKDDR FVPVRKFKGN NGVVVLRDRE PKEPVALIET VRQMKDVNAP LPTPFKVDDN VDFPSA

UniProtKB: 26S proteasome regulatory subunit RPN2

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分子 #12: 26S proteasome regulatory subunit RPN3

分子名称: 26S proteasome regulatory subunit RPN3 / タイプ: protein_or_peptide / ID: 12 / コピー数: 1 / 光学異性体: LEVO
由来(天然)生物種: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (パン酵母)
株: ATCC 204508 / S288c
分子量理論値: 60.464605 KDa
配列文字列: MASTAVMMDV DSSGVNDLHH SEKKYAEEDQ VQELLKVLNE ISKTTLTLDP RYIWRSLKDL SSLRNQELLN AETLCFTVNV LYPDSSSFK KNLLKFITSN HKSSVPGSAE LRNSYPASFY SVNTEKKTIE VTAEINCFMH LLVQLFLWDS KELEQLVEFN R KVVIPNLL ...文字列:
MASTAVMMDV DSSGVNDLHH SEKKYAEEDQ VQELLKVLNE ISKTTLTLDP RYIWRSLKDL SSLRNQELLN AETLCFTVNV LYPDSSSFK KNLLKFITSN HKSSVPGSAE LRNSYPASFY SVNTEKKTIE VTAEINCFMH LLVQLFLWDS KELEQLVEFN R KVVIPNLL CYYNLRSLNL INAKLWFYIY LSHETLARSS EEINSDNQNI ILRSTMMKFL KIASLKHDNE TKAMLINLIL RD FLNNGEV DSASDFISKL EYPHTDVSSS LEARYFFYLS KINAIQLDYS TANEYIIAAI RKAPHNSKSL GFLQQSNKLH CCI QLLMGD IPELSFFHQS NMQKSLLPYY HLTKAVKLGD LKKFTSTITK YKQLLLKDDT YQLCVRLRSN VIKTGIRIIS LTYK KISLR DICLKLNLDS EQTVEYMVSR AIRDGVIEAK INHEDGFIET TELLNIYDSE DPQQVFDERI KFANQLHDEY LVSMR YPED KKTQQNEKSE NGENDDDTLD GDLMDDMSDI SDLDDLGFL

UniProtKB: 26S proteasome regulatory subunit RPN3

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分子 #13: 26S proteasome regulatory subunit RPN12

分子名称: 26S proteasome regulatory subunit RPN12 / タイプ: protein_or_peptide / ID: 13 / コピー数: 1 / 光学異性体: LEVO
由来(天然)生物種: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (パン酵母)
株: ATCC 204508 / S288c
分子量理論値: 31.952119 KDa
配列文字列: MPSLAELTKS LSIAFENGDY AACEKLLPPI KIELIKNNLL IPDLSIQNDI YLNDLMITKR ILEVGALASI QTFNFDSFEN YFNQLKPYY FSNNHKLSES DKKSKLISLY LLNLLSQNNT TKFHSELQYL DKHIKNLEDD SLLSYPIKLD RWLMEGSYQK A WDLLQSGS ...文字列:
MPSLAELTKS LSIAFENGDY AACEKLLPPI KIELIKNNLL IPDLSIQNDI YLNDLMITKR ILEVGALASI QTFNFDSFEN YFNQLKPYY FSNNHKLSES DKKSKLISLY LLNLLSQNNT TKFHSELQYL DKHIKNLEDD SLLSYPIKLD RWLMEGSYQK A WDLLQSGS QNISEFDSFT DILKSAIRDE IAKNTELSYD FLPLSNIKAL LFFNNEKETE KFALERNWPI VNSKVYFNNQ SK EKADYED EMMHEEDQKT NIIEKAMDYA ISIENIV

UniProtKB: 26S proteasome regulatory subunit RPN12

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分子 #14: 26S proteasome regulatory subunit RPN7

分子名称: 26S proteasome regulatory subunit RPN7 / タイプ: protein_or_peptide / ID: 14 / コピー数: 1 / 光学異性体: LEVO
由来(天然)生物種: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (パン酵母)
株: ATCC 204508 / S288c
分子量理論値: 49.016367 KDa
配列文字列: MVDVEEKSQE VEYVDPTVNR VPNYEVSEKA FLLTQSKVSI EQRKEAAEFV LAKIKEEEMA PYYKYLCEEY LVNNGQSDLE HDEKSDSLN EWIKFDQELY NELCKKNESK IKELNEKIQK LEEDDEGELE QAQAWINLGE YYAQIGDKDN AEKTLGKSLS K AISTGAKI ...文字列:
MVDVEEKSQE VEYVDPTVNR VPNYEVSEKA FLLTQSKVSI EQRKEAAEFV LAKIKEEEMA PYYKYLCEEY LVNNGQSDLE HDEKSDSLN EWIKFDQELY NELCKKNESK IKELNEKIQK LEEDDEGELE QAQAWINLGE YYAQIGDKDN AEKTLGKSLS K AISTGAKI DVMLTIARLG FFYNDQLYVK EKLEAVNSMI EKGGDWERRN RYKTYYGIHC LAVRNFKEAA KLLVDSLATF TS IELTSYE SIATYASVTG LFTLERTDLK SKVIDSPELL SLISTTAALQ SISSLTISLY ASDYASYFPY LLETYANVLI PCK YLNRHA DFFVREMRRK VYAQLLESYK TLSLKSMASA FGVSVAFLDN DLGKFIPNKQ LNCVIDRVNG IVETNRPDNK NAQY HLLVK QGDGLLTKLQ KYGAAVRLTG SDRV

UniProtKB: 26S proteasome regulatory subunit RPN7

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分子 #15: 26S proteasome regulatory subunit RPN6

分子名称: 26S proteasome regulatory subunit RPN6 / タイプ: protein_or_peptide / ID: 15 / コピー数: 1 / 光学異性体: LEVO
由来(天然)生物種: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (パン酵母)
株: ATCC 204508 / S288c
分子量理論値: 49.839812 KDa
配列文字列: MSLPGSKLEE ARRLVNEKQY NEAEQVYLSL LDKDSSQSSA AAGASVDDKR RNEQETSILE LGQLYVTMGA KDKLREFIPH STEYMMQFA KSKTVKVLKT LIEKFEQVPD SLDDQIFVCE KSIEFAKREK RVFLKHSLSI KLATLHYQKK QYKDSLALIN D LLREFKKL ...文字列:
MSLPGSKLEE ARRLVNEKQY NEAEQVYLSL LDKDSSQSSA AAGASVDDKR RNEQETSILE LGQLYVTMGA KDKLREFIPH STEYMMQFA KSKTVKVLKT LIEKFEQVPD SLDDQIFVCE KSIEFAKREK RVFLKHSLSI KLATLHYQKK QYKDSLALIN D LLREFKKL DDKPSLVDVH LLESKVYHKL RNLAKSKASL TAARTAANSI YCPTQTVAEL DLMSGILHCE DKDYKTAFSY FF ESFESYH NLTTHNSYEK ACQVLKYMLL SKIMLNLIDD VKNILNAKYT KETYQSRGID AMKAVAEAYN NRSLLDFNTA LKQ YEKELM GDELTRSHFN ALYDTLLESN LCKIIEPFEC VEISHISKII GLDTQQVEGK LSQMILDKIF YGVLDQGNGW LYVY ETPNQ DATYDSALEL VGQLNKVVDQ LFEKASVLY

UniProtKB: 26S proteasome regulatory subunit RPN6

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分子 #16: 26S protease regulatory subunit 8 homolog

分子名称: 26S protease regulatory subunit 8 homolog / タイプ: protein_or_peptide / ID: 16 / コピー数: 1 / 光学異性体: LEVO
由来(天然)生物種: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (パン酵母)
株: ATCC 204508 / S288c
分子量理論値: 45.342742 KDa
配列文字列: MTAAVTSSNI VLETHESGIK PYFEQKIQET ELKIRSKTEN VRRLEAQRNA LNDKVRFIKD ELRLLQEPGS YVGEVIKIVS DKKVLVKVQ PEGKYIVDVA KDINVKDLKA SQRVCLRSDS YMLHKVLENK ADPLVSLMMV EKVPDSTYDM VGGLTKQIKE I KEVIELPV ...文字列:
MTAAVTSSNI VLETHESGIK PYFEQKIQET ELKIRSKTEN VRRLEAQRNA LNDKVRFIKD ELRLLQEPGS YVGEVIKIVS DKKVLVKVQ PEGKYIVDVA KDINVKDLKA SQRVCLRSDS YMLHKVLENK ADPLVSLMMV EKVPDSTYDM VGGLTKQIKE I KEVIELPV KHPELFESLG IAQPKGVILY GPPGTGKTLL ARAVAHHTDC KFIRVSGAEL VQKYIGEGSR MVRELFVMAR EH APSIIFM DEIDSIGSTR VEGSGGGDSE VQRTMLELLN QLDGFETSKN IKIIMATNRL DILDPALLRP GRIDRKIEFP PPS VAARAE ILRIHSRKMN LTRGINLRKV AEKMNGCSGA DVKGVCTEAG MYALRERRIH VTQEDFELAV GKVMNKNQET AISV AKLFK

UniProtKB: 26S proteasome regulatory subunit 8 homolog

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分子 #17: 26S protease subunit RPT4

分子名称: 26S protease subunit RPT4 / タイプ: protein_or_peptide / ID: 17 / コピー数: 1 / 光学異性体: LEVO
由来(天然)生物種: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (パン酵母)
株: ATCC 204508 / S288c
分子量理論値: 49.480137 KDa
配列文字列: MSEEQDPLLA GLGETSGDNH TQQSHEQQPE QPQETEEHHE EEPSRVDPEQ EAHNKALNQF KRKLLEHRRY DDQLKQRRQN IRDLEKLYD KTENDIKALQ SIGQLIGEVM KELSEEKYIV KASSGPRYIV GVRNSVDRSK LKKGVRVTLD ITTLTIMRIL P RETDPLVY ...文字列:
MSEEQDPLLA GLGETSGDNH TQQSHEQQPE QPQETEEHHE EEPSRVDPEQ EAHNKALNQF KRKLLEHRRY DDQLKQRRQN IRDLEKLYD KTENDIKALQ SIGQLIGEVM KELSEEKYIV KASSGPRYIV GVRNSVDRSK LKKGVRVTLD ITTLTIMRIL P RETDPLVY NMTSFEQGEI TFDGIGGLTE QIRELREVIE LPLKNPEIFQ RVGIKPPKGV LLYGPPGTGK TLLAKAVAAT IG ANFIFSP ASGIVDKYIG ESARIIREMF AYAKEHEPCI IFMDEVDAIG GRRFSEGTSA DREIQRTLME LLTQMDGFDN LGQ TKIIMA TNRPDTLDPA LLRPGRLDRK VEIPLPNEAG RLEIFKIHTA KVKKTGEFDF EAAVKMSDGF NGADIRNCAT EAGF FAIRD DRDHINPDDL MKAVRKVAEV KKLEGTIEYQ KL

UniProtKB: 26S proteasome subunit RPT4

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分子 #18: 26S protease regulatory subunit 6A

分子名称: 26S protease regulatory subunit 6A / タイプ: protein_or_peptide / ID: 18 / コピー数: 1 / 光学異性体: LEVO
由来(天然)生物種: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (パン酵母)
株: ATCC 204508 / S288c
分子量理論値: 48.315727 KDa
配列文字列: MATLEELDAQ TLPGDDELDQ EILNLSTQEL QTRAKLLDNE IRIFRSELQR LSHENNVMLE KIKDNKEKIK NNRQLPYLVA NVVEVMDMN EIEDKENSES TTQGGNVNLD NTAVGKAAVV KTSSRQTVFL PMVGLVDPDK LKPNDLVGVN KDSYLILDTL P SEFDSRVK ...文字列:
MATLEELDAQ TLPGDDELDQ EILNLSTQEL QTRAKLLDNE IRIFRSELQR LSHENNVMLE KIKDNKEKIK NNRQLPYLVA NVVEVMDMN EIEDKENSES TTQGGNVNLD NTAVGKAAVV KTSSRQTVFL PMVGLVDPDK LKPNDLVGVN KDSYLILDTL P SEFDSRVK AMEVDEKPTE TYSDVGGLDK QIEELVEAIV LPMKRADKFK DMGIRAPKGA LMYGPPGTGK TLLARACAAQ TN ATFLKLA APQLVQMYIG EGAKLVRDAF ALAKEKAPTI IFIDELDAIG TKRFDSEKSG DREVQRTMLE LLNQLDGFSS DDR VKVLAA TNRVDVLDPA LLRSGRLDRK IEFPLPSEDS RAQILQIHSR KMTTDDDINW QELARSTDEF NGAQLKAVTV EAGM IALRN GQSSVKHEDF VEGISEVQAR KSKSVSFYA

UniProtKB: 26S proteasome regulatory subunit 6A

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分子 #19: 26S proteasome regulatory subunit RPN8

分子名称: 26S proteasome regulatory subunit RPN8 / タイプ: protein_or_peptide / ID: 19 / コピー数: 1 / 光学異性体: LEVO
由来(天然)生物種: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (パン酵母)
株: ATCC 204508 / S288c
分子量理論値: 38.365508 KDa
配列文字列: MSLQHEKVTI APLVLLSALD HYERTQTKEN KRCVGVILGD ANSSTIRVTN SFALPFEEDE KNSDVWFLDH NYIENMNEMC KKINAKEKL IGWYHSGPKL RASDLKINEL FKKYTQNNPL LLIVDVKQQG VGLPTDAYVA IEQVKDDGTS TEKTFLHLPC T IEAEEAEE ...文字列:
MSLQHEKVTI APLVLLSALD HYERTQTKEN KRCVGVILGD ANSSTIRVTN SFALPFEEDE KNSDVWFLDH NYIENMNEMC KKINAKEKL IGWYHSGPKL RASDLKINEL FKKYTQNNPL LLIVDVKQQG VGLPTDAYVA IEQVKDDGTS TEKTFLHLPC T IEAEEAEE IGVEHLLRDV RDQAAGGLSI RLTNQLKSLK GLQSKLKDVV EYLDKVINKE LPINHTILGK LQDVFNLLPN LG TPDDDEI DVENHDRINI SNNLQKALTV KTNDELMVIY ISNLVRSIIA FDDLIENKIQ NKKIQEQRVK DKQSKVSDDS ESE SGDKEA TAPLIQRKNK KN

UniProtKB: 26S proteasome regulatory subunit RPN8

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分子 #20: 26S proteasome regulatory subunit RPN10

分子名称: 26S proteasome regulatory subunit RPN10 / タイプ: protein_or_peptide / ID: 20 / コピー数: 1 / 光学異性体: LEVO
由来(天然)生物種: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (パン酵母)
株: ATCC 204508 / S288c
分子量理論値: 29.776098 KDa
配列文字列: MVLEATVLVI DNSEYSRNGD FPRTRFEAQI DSVEFIFQAK RNSNPENTVG LISGAGANPR VLSTFTAEFG KILAGLHDTQ IEGKLHMAT ALQIAQLTLK HRQNKVQHQR IVAFVCSPIS DSRDELIRLA KTLKKNNVAV DIINFGEIEQ NTELLDEFIA A VNNPQEET ...文字列:
MVLEATVLVI DNSEYSRNGD FPRTRFEAQI DSVEFIFQAK RNSNPENTVG LISGAGANPR VLSTFTAEFG KILAGLHDTQ IEGKLHMAT ALQIAQLTLK HRQNKVQHQR IVAFVCSPIS DSRDELIRLA KTLKKNNVAV DIINFGEIEQ NTELLDEFIA A VNNPQEET SHLLTVTPGP RLLYENIASS PIILEEGSSG MGAFGGSGGD SDANGTFMDF GVDPSMDPEL AMALRLSMEE EQ QRQERLR QQQQQQDQPE QSEQPEQHQD K

UniProtKB: 26S proteasome regulatory subunit RPN10

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分子 #21: 26S proteasome regulatory subunit RPN9

分子名称: 26S proteasome regulatory subunit RPN9 / タイプ: protein_or_peptide / ID: 21 / コピー数: 1 / 光学異性体: LEVO
由来(天然)生物種: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (パン酵母)
株: ATCC 204508 / S288c
分子量理論値: 45.839348 KDa
配列文字列: MFNNHEIDTI LSTLRMEADP SLHPLFEQFE KFYEEKLWFQ LSESLTKFFD DAKSTPLRLR LYDNFVSKFY DKINQLSVVK YLLASLKDS KDFDESLKYL DDLKAQFQEL DSKKQRNNGS KDHGDGILLI DSEIARTYLL KNDLVKARDL LDDLEKTLDK K DSIPLRIT ...文字列:
MFNNHEIDTI LSTLRMEADP SLHPLFEQFE KFYEEKLWFQ LSESLTKFFD DAKSTPLRLR LYDNFVSKFY DKINQLSVVK YLLASLKDS KDFDESLKYL DDLKAQFQEL DSKKQRNNGS KDHGDGILLI DSEIARTYLL KNDLVKARDL LDDLEKTLDK K DSIPLRIT NSFYSTNSQY FKFKNDFNSF YYTSLLYLST LEPSTSITLA ERQQLAYDLS ISALLGDKIY NFGELLHHPI ME TIVNDSN YDWLFQLLNA LTVGDFDKFD SLIKVQISKI PILAQHESFL RQKICLMTLI ETVFVKNIRM LSFEDISKAT HLP KDNVEH LVMRAISLGL LKGSIDQVNE LVTISWVQPR IISGDQITKM KDRLVEWNDQ VEKLGKKMEA RGQSIWV

UniProtKB: 26S proteasome regulatory subunit RPN9

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分子 #22: 26S proteasome regulatory subunit RPN5

分子名称: 26S proteasome regulatory subunit RPN5 / タイプ: protein_or_peptide / ID: 22 / コピー数: 1 / 光学異性体: LEVO
由来(天然)生物種: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (パン酵母)
株: ATCC 204508 / S288c
分子量理論値: 51.840352 KDa
配列文字列: MSRDAPIKAD KDYSQILKEE FPKIDSLAQN DCNSALDQLL VLEKKTRQAS DLASSKEVLA KIVDLLASRN KWDDLNEQLT LLSKKHGQL KLSIQYMIQK VMEYLKSSKS LDLNTRISVI ETIRVVTENK IFVEVERARV TKDLVEIKKE EGKIDEAADI L CELQVETY ...文字列:
MSRDAPIKAD KDYSQILKEE FPKIDSLAQN DCNSALDQLL VLEKKTRQAS DLASSKEVLA KIVDLLASRN KWDDLNEQLT LLSKKHGQL KLSIQYMIQK VMEYLKSSKS LDLNTRISVI ETIRVVTENK IFVEVERARV TKDLVEIKKE EGKIDEAADI L CELQVETY GSMEMSEKIQ FILEQMELSI LKGDYSQATV LSRKILKKTF KNPKYESLKL EYYNLLVKIS LHKREYLEVA QY LQEIYQT DAIKSDEAKW KPVLSHIVYF LVLSPYGNLQ NDLIHKIQND NNLKKLESQE SLVKLFTTNE LMRWPIVQKT YEP VLNEDD LAFGGEANKH HWEDLQKRVI EHNLRVISEY YSRITLLRLN ELLDLTESQT ETYISDLVNQ GIIYAKVNRP AKIV NFEKP KNSSQLLNEW SHNVDELLEH IETIGHLITK EEIMHGLQAK

UniProtKB: 26S proteasome regulatory subunit RPN5

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分子 #23: 26S protease regulatory subunit 7 homolog

分子名称: 26S protease regulatory subunit 7 homolog / タイプ: protein_or_peptide / ID: 23 / コピー数: 1 / 光学異性体: LEVO
由来(天然)生物種: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (パン酵母)
株: ATCC 204508 / S288c
分子量理論値: 52.054891 KDa
配列文字列: MPPKEDWEKY KAPLEDDDKK PDDDKIVPLT EGDIQVLKSY GAAPYAAKLK QTENDLKDIE ARIKEKAGVK ESDTGLAPSH LWDIMGDRQ RLGEEHPLQV ARCTKIIKGN GESDETTTDN NNSGNSNSNS NQQSTDADED DEDAKYVINL KQIAKFVVGL G ERVSPTDI ...文字列:
MPPKEDWEKY KAPLEDDDKK PDDDKIVPLT EGDIQVLKSY GAAPYAAKLK QTENDLKDIE ARIKEKAGVK ESDTGLAPSH LWDIMGDRQ RLGEEHPLQV ARCTKIIKGN GESDETTTDN NNSGNSNSNS NQQSTDADED DEDAKYVINL KQIAKFVVGL G ERVSPTDI EEGMRVGVDR SKYNIELPLP PRIDPSVTMM TVEEKPDVTY SDVGGCKDQI EKLREVVELP LLSPERFATL GI DPPKGIL LYGPPGTGKT LCARAVANRT DATFIRVIGS ELVQKYVGEG ARMVRELFEM ARTKKACIIF FDEIDAVGGA RFD DGAGGD NEVQRTMLEL ITQLDGFDPR GNIKVMFATN RPNTLDPALL RPGRIDRKVE FSLPDLEGRA NIFRIHSKSM SVER GIRWE LISRLCPNST GAELRSVCTE AGMFAIRARR KVATEKDFLK AVDKVISGYK KFSSTSRYMQ YN

UniProtKB: 26S proteasome regulatory subunit 7 homolog

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分子 #24: Proteasome subunit alpha type-3

分子名称: Proteasome subunit alpha type-3 / タイプ: protein_or_peptide / ID: 24 / コピー数: 2 / 光学異性体: LEVO / EC番号: proteasome endopeptidase complex
由来(天然)生物種: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (パン酵母)
株: ATCC 204508 / S288c
分子量理論値: 28.74823 KDa
配列文字列: MGSRRYDSRT TIFSPEGRLY QVEYALESIS HAGTAIGIMA SDGIVLAAER KVTSTLLEQD TSTEKLYKLN DKIAVAVAGL TADAEILIN TARIHAQNYL KTYNEDIPVE ILVRRLSDIK QGYTQHGGLR PFGVSFIYAG YDDRYGYQLY TSNPSGNYTG W KAISVGAN ...文字列:
MGSRRYDSRT TIFSPEGRLY QVEYALESIS HAGTAIGIMA SDGIVLAAER KVTSTLLEQD TSTEKLYKLN DKIAVAVAGL TADAEILIN TARIHAQNYL KTYNEDIPVE ILVRRLSDIK QGYTQHGGLR PFGVSFIYAG YDDRYGYQLY TSNPSGNYTG W KAISVGAN TSAAQTLLQM DYKDDMKVDD AIELALKTLS KTTDSSALTY DRLEFATIRK GANDGEVYQK IFKPQEIKDI LV KTGITKK DEDEEADEDM K

UniProtKB: Proteasome subunit alpha type-3

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分子 #25: Proteasome subunit alpha type-2

分子名称: Proteasome subunit alpha type-2 / タイプ: protein_or_peptide / ID: 25 / コピー数: 2 / 光学異性体: LEVO / EC番号: proteasome endopeptidase complex
由来(天然)生物種: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (パン酵母)
株: ATCC 204508 / S288c
分子量理論値: 27.191828 KDa
配列文字列: MTDRYSFSLT TFSPSGKLGQ IDYALTAVKQ GVTSLGIKAT NGVVIATEKK SSSPLAMSET LSKVSLLTPD IGAVYSGMGP DYRVLVDKS RKVAHTSYKR IYGEYPPTKL LVSEVAKIMQ EATQSGGVRP FGVSLLIAGH DEFNGFSLYQ VDPSGSYFPW K ATAIGKGS ...文字列:
MTDRYSFSLT TFSPSGKLGQ IDYALTAVKQ GVTSLGIKAT NGVVIATEKK SSSPLAMSET LSKVSLLTPD IGAVYSGMGP DYRVLVDKS RKVAHTSYKR IYGEYPPTKL LVSEVAKIMQ EATQSGGVRP FGVSLLIAGH DEFNGFSLYQ VDPSGSYFPW K ATAIGKGS VAAKTFLEKR WNDELELEDA IHIALLTLKE SVEGEFNGDT IELAIIGDEN PDLLGYTGIP TDKGPRFRKL TS QEINDRL EAL

UniProtKB: Proteasome subunit alpha type-2

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分子 #26: Proteasome subunit beta type-1

分子名称: Proteasome subunit beta type-1 / タイプ: protein_or_peptide / ID: 26 / コピー数: 2 / 光学異性体: LEVO / EC番号: proteasome endopeptidase complex
由来(天然)生物種: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (パン酵母)
株: ATCC 204508 / S288c
分子量理論値: 23.573604 KDa
配列文字列: MNGIQVDINR LKKGEVSLGT SIMAVTFKDG VILGADSRTT TGAYIANRVT DKLTRVHDKI WCCRSGSAAD TQAIADIVQY HLELYTSQY GTPSTETAAS VFKELCYENK DNLTAGIIVA GYDDKNKGEV YTIPLGGSVH KLPYAIAGSG STFIYGYCDK N FRENMSKE ...文字列:
MNGIQVDINR LKKGEVSLGT SIMAVTFKDG VILGADSRTT TGAYIANRVT DKLTRVHDKI WCCRSGSAAD TQAIADIVQY HLELYTSQY GTPSTETAAS VFKELCYENK DNLTAGIIVA GYDDKNKGEV YTIPLGGSVH KLPYAIAGSG STFIYGYCDK N FRENMSKE ETVDFIKHSL SQAIKWDGSS GGVIRMVVLT AAGVERLIFY PDEYEQL

UniProtKB: Proteasome subunit beta type-1

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分子 #27: Proteasome subunit beta type-4

分子名称: Proteasome subunit beta type-4 / タイプ: protein_or_peptide / ID: 27 / コピー数: 2 / 光学異性体: LEVO / EC番号: proteasome endopeptidase complex
由来(天然)生物種: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (パン酵母)
株: ATCC 204508 / S288c
分子量理論値: 22.545676 KDa
配列文字列: MDIILGIRVQ DSVILASSKA VTRGISVLKD SDDKTRQLSP HTLMSFAGEA GDTVQFAEYI QANIQLYSIR EDYELSPQAV SSFVRQELA KSIRSRRPYQ VNVLIGGYDK KKNKPELYQI DYLGTKVELP YGAHGYSGFY TFSLLDHHYR PDMTTEEGLD L LKLCVQEL ...文字列:
MDIILGIRVQ DSVILASSKA VTRGISVLKD SDDKTRQLSP HTLMSFAGEA GDTVQFAEYI QANIQLYSIR EDYELSPQAV SSFVRQELA KSIRSRRPYQ VNVLIGGYDK KKNKPELYQI DYLGTKVELP YGAHGYSGFY TFSLLDHHYR PDMTTEEGLD L LKLCVQEL EKRMPMDFKG VIVKIVDKDG IRQVDDFQAQ

UniProtKB: Proteasome subunit beta type-4

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分子 #28: Proteasome subunit beta type-5

分子名称: Proteasome subunit beta type-5 / タイプ: protein_or_peptide / ID: 28 / コピー数: 2 / 光学異性体: LEVO / EC番号: proteasome endopeptidase complex
由来(天然)生物種: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (パン酵母)
株: ATCC 204508 / S288c
分子量理論値: 31.670539 KDa
配列文字列: MQAIADSFSV PNRLVKELQY DNEQNLESDF VTGASQFQRL APSLTVPPIA SPQQFLRAHT DDSRNPDCKI KIAHGTTTLA FRFQGGIIV AVDSRATAGN WVASQTVKKV IEINPFLLGT MAGGAADCQF WETWLGSQCR LHELREKERI SVAAASKILS N LVYQYKGA ...文字列:
MQAIADSFSV PNRLVKELQY DNEQNLESDF VTGASQFQRL APSLTVPPIA SPQQFLRAHT DDSRNPDCKI KIAHGTTTLA FRFQGGIIV AVDSRATAGN WVASQTVKKV IEINPFLLGT MAGGAADCQF WETWLGSQCR LHELREKERI SVAAASKILS N LVYQYKGA GLSMGTMICG YTRKEGPTIY YVDSDGTRLK GDIFCVGSGQ TFAYGVLDSN YKWDLSVEDA LYLGKRSILA AA HRDAYSG GSVNLYHVTE DGWIYHGNHD VGELFWKVKE EEGSFNNVIG

UniProtKB: Proteasome subunit beta type-5

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分子 #29: Proteasome subunit beta type-6

分子名称: Proteasome subunit beta type-6 / タイプ: protein_or_peptide / ID: 29 / コピー数: 2 / 光学異性体: LEVO / EC番号: proteasome endopeptidase complex
由来(天然)生物種: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (パン酵母)
株: ATCC 204508 / S288c
分子量理論値: 26.905076 KDa
配列文字列: MATIASEYSS EASNTPIEHQ FNPYGDNGGT ILGIAGEDFA VLAGDTRNIT DYSINSRYEP KVFDCGDNIV MSANGFAADG DALVKRFKN SVKWYHFDHN DKKLSINSAA RNIQHLLYGK RFFPYYVHTI IAGLDEDGKG AVYSFDPVGS YEREQCRAGG A AASLIMPF ...文字列:
MATIASEYSS EASNTPIEHQ FNPYGDNGGT ILGIAGEDFA VLAGDTRNIT DYSINSRYEP KVFDCGDNIV MSANGFAADG DALVKRFKN SVKWYHFDHN DKKLSINSAA RNIQHLLYGK RFFPYYVHTI IAGLDEDGKG AVYSFDPVGS YEREQCRAGG A AASLIMPF LDNQVNFKNQ YEPGTNGKVK KPLKYLSVEE VIKLVRDSFT SATERHIQVG DGLEILIVTK DGVRKEFYEL KR D

UniProtKB: Proteasome subunit beta type-6

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分子 #30: Proteasome subunit beta type-7

分子名称: Proteasome subunit beta type-7 / タイプ: protein_or_peptide / ID: 30 / コピー数: 2 / 光学異性体: LEVO / EC番号: proteasome endopeptidase complex
由来(天然)生物種: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (パン酵母)
株: ATCC 204508 / S288c
分子量理論値: 29.471289 KDa
配列文字列: MNHDPFSWGR PADSTYGAYN TQIANAGASP MVNTQQPIVT GTSVISMKYD NGVIIAADNL GSYGSLLRFN GVERLIPVGD NTVVGISGD ISDMQHIERL LKDLVTENAY DNPLADAEEA LEPSYIFEYL ATVMYQRRSK MNPLWNAIIV AGVQSNGDQF L RYVNLLGV ...文字列:
MNHDPFSWGR PADSTYGAYN TQIANAGASP MVNTQQPIVT GTSVISMKYD NGVIIAADNL GSYGSLLRFN GVERLIPVGD NTVVGISGD ISDMQHIERL LKDLVTENAY DNPLADAEEA LEPSYIFEYL ATVMYQRRSK MNPLWNAIIV AGVQSNGDQF L RYVNLLGV TYSSPTLATG FGAHMANPLL RKVVDRESDI PKTTVQVAEE AIVNAMRVLY YRDARSSRNF SLAIIDKNTG LT FKKNLQV ENMKWDFAKD IKGYGTQKI

UniProtKB: Proteasome subunit beta type-7

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分子 #31: 26S proteasome regulatory subunit RPN13

分子名称: 26S proteasome regulatory subunit RPN13 / タイプ: protein_or_peptide / ID: 31 / コピー数: 1 / 光学異性体: LEVO
由来(天然)生物種: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (パン酵母)
株: ATCC 204508 / S288c
分子量理論値: 17.919002 KDa
配列文字列:
MSMSSTVIKF RAGVCEYNED SRLCTPIPVQ GEIEIKPNEE EELGFWDFEW RPTEKPVGRE LDPISLILIP GETMWVPIKS SKSGRIFAL VFSSNERYFF WLQEKNSGNL PLNELSAKDK EIYNKMIGVL NNSSESDEEE SNDEKQKAQD VDVSMQD

UniProtKB: 26S proteasome regulatory subunit RPN13

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分子 #32: 26S proteasome regulatory subunit RPN1

分子名称: 26S proteasome regulatory subunit RPN1 / タイプ: protein_or_peptide / ID: 32 / コピー数: 1 / 光学異性体: LEVO
由来(天然)生物種: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (パン酵母)
株: ATCC 204508 / S288c
分子量理論値: 109.601906 KDa
配列文字列: MVDESDKKQQ TIDEQSQISP EKQTPNKKDK KKEEEEQLSE EDAKLKTDLE LLVERLKEDD SSLYEASLNA LKESIKNSTS SMTAVPKPL KFLRPTYPDL CSIYDKWTDP NLKSSLADVL SILAMTYSEN GKHDSLRYRL LSDVSDFEGW GHEYIRHLAL E IGEVYNDQ ...文字列:
MVDESDKKQQ TIDEQSQISP EKQTPNKKDK KKEEEEQLSE EDAKLKTDLE LLVERLKEDD SSLYEASLNA LKESIKNSTS SMTAVPKPL KFLRPTYPDL CSIYDKWTDP NLKSSLADVL SILAMTYSEN GKHDSLRYRL LSDVSDFEGW GHEYIRHLAL E IGEVYNDQ VEKDAEDETS SDGSKSDGSA ATSGFEFSKE DTLRLCLDIV PYFLKHNGEE DAVDLLLEIE SIDKLPQFVD EN TFQRVCQ YMVACVPLLP PPEDVAFLKT AYSIYLSQNE LTDAIALAVR LGEEDMIRSV FDATSDPVMH KQLAYILAAQ KTS FEYEGV QDIIGNGKLS EHFLYLAKEL NLTGPKVPED IYKSHLDNSK SVFSSAGLDS AQQNLASSFV NGFLNLGYCN DKLI VDNDN WVYKTKGDGM TSAVASIGSI YQWNLDGLQQ LDKYLYVDEP EVKAGALLGI GISASGVHDG EVEPALLLLQ DYVTN PDTK ISSAAILGLG IAFAGSKNDE VLGLLLPIAA STDLPIETAA MASLALAHVF VGTCNGDITT SIMDNFLERT AIELKT DWV RFLALALGIL YMGQGEQVDD VLETISAIEH PMTSAIEVLV GSCAYTGTGD VLLIQDLLHR LTPKNVKGEE DADEEET AE GQTNSISDFL GEQVNEPTKN EEAEIEVDEM EVDAEGEEVE VKAEITEKKN GESLEGEEIK SEEKKGKSSD KDATTDGK N DDEEEEKEAG IVDELAYAVL GIALIALGED IGKEMSLRHF GHLMHYGNEH IRRMVPLAMG IVSVSDPQMK VFDTLTRFS HDADLEVSMN SIFAMGLCGA GTNNARLAQL LRQLASYYSR EQDALFITRL AQGLLHLGKG TMTMDVFNDA HVLNKVTLAS ILTTAVGLV SPSFMLKHHQ LFYMLNAGIR PKFILALNDE GEPIKVNVRV GQAVETVGQA GRPKKITGWI TQSTPVLLNH G ERAELETD EYISYTSHIE GVVILKKNPD YREEE

UniProtKB: 26S proteasome regulatory subunit RPN1

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分子 #33: Ubiquitin carboxyl-terminal hydrolase RPN11

分子名称: Ubiquitin carboxyl-terminal hydrolase RPN11 / タイプ: protein_or_peptide / ID: 33 / コピー数: 1 / 光学異性体: LEVO / EC番号: ubiquitinyl hydrolase 1
由来(天然)生物種: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (パン酵母)
株: ATCC 204508 / S288c
分子量理論値: 34.442281 KDa
配列文字列: MERLQRLMMN SKVGSADTGR DDTKETVYIS SIALLKMLKH GRAGVPMEVM GLMLGEFVDD YTVNVVDVFA MPQSGTGVSV EAVDDVFQA KMMDMLKQTG RDQMVVGWYH SHPGFGCWLS SVDVNTQKSF EQLNSRAVAV VVDPIQSVKG KVVIDAFRLI D TGALINNL ...文字列:
MERLQRLMMN SKVGSADTGR DDTKETVYIS SIALLKMLKH GRAGVPMEVM GLMLGEFVDD YTVNVVDVFA MPQSGTGVSV EAVDDVFQA KMMDMLKQTG RDQMVVGWYH SHPGFGCWLS SVDVNTQKSF EQLNSRAVAV VVDPIQSVKG KVVIDAFRLI D TGALINNL EPRQTTSNTG LLNKANIQAL IHGLNRHYYS LNIDYHKTAK ETKMLMNLHK EQWQSGLKMY DYEEKEESNL AA TKSMVKI AEQYSKRIEE EKELTEEELK TRYVGRQDPK KHLSETADET LENNIVSVLT AGVNSVAIK

UniProtKB: Ubiquitin carboxyl-terminal hydrolase RPN11

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実験情報

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構造解析

手法クライオ電子顕微鏡法
解析単粒子再構成法
試料の集合状態cell

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試料調製

緩衝液pH: 7.5
凍結凍結剤: ETHANE

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電子顕微鏡法

顕微鏡FEI TITAN KRIOS
撮影フィルム・検出器のモデル: FEI FALCON II (4k x 4k)
平均電子線量: 25.0 e/Å2
電子線加速電圧: 300 kV / 電子線源: FIELD EMISSION GUN
電子光学系照射モード: FLOOD BEAM / 撮影モード: BRIGHT FIELD
実験機器
モデル: Titan Krios / 画像提供: FEI Company

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画像解析

初期モデルモデルのタイプ: EMDB MAP
最終 再構成解像度のタイプ: BY AUTHOR / 解像度: 6.3 Å / 解像度の算出法: FSC 0.143 CUT-OFF / 使用した粒子像数: 26000
初期 角度割当タイプ: PROJECTION MATCHING
最終 角度割当タイプ: PROJECTION MATCHING

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万見について

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お知らせ

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2022年2月9日: EMDBエントリの付随情報ファイルのフォーマットが新しくなりました

EMDBエントリの付随情報ファイルのフォーマットが新しくなりました

  • EMDBのヘッダファイルのバージョン3が、公式のフォーマットとなりました。
  • これまでは公式だったバージョン1.9は、アーカイブから削除されます。

関連情報:EMDBヘッダ

外部リンク:wwPDBはEMDBデータモデルのバージョン3へ移行します

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2020年8月12日: 新型コロナ情報

新型コロナ情報

URL: https://pdbj.org/emnavi/covid19.php

新ページ: EM Navigatorに新型コロナウイルスの特設ページを開設しました。

関連情報:Covid-19情報 / 2020年3月5日: 新型コロナウイルスの構造データ

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2020年3月5日: 新型コロナウイルスの構造データ

新型コロナウイルスの構造データ

関連情報:万見生物種 / 2020年8月12日: 新型コロナ情報

外部リンク:COVID-19特集ページ - PDBj / 今月の分子2020年2月：コロナウイルスプロテーアーゼ

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2019年1月31日: EMDBのIDの桁数の変更

EMDBのIDの桁数の変更

  • EMDBエントリに付与されているアクセスコード(EMDB-ID)は4桁の数字(例、EMD-1234)でしたが、間もなく枯渇します。これまでの4桁のID番号は4桁のまま変更されませんが、4桁の数字を使い切った後に発行されるIDは5桁以上の数字(例、EMD-12345)になります。5桁のIDは2019年の春頃から発行される見通しです。
  • EM Navigator/万見では、接頭語「EMD-」は省略されています。

関連情報:Q: 「EMD」とは何ですか？ / 万見/EM NavigatorにおけるID/アクセスコードの表記

外部リンク:EMDB Accession Codes are Changing Soon! / PDBjへお問い合わせ

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2017年7月12日: PDB大規模アップデート

PDB大規模アップデート

  • 新バージョンのPDBx/mmCIF辞書形式に基づくデータがリリースされました。
  • 今回の更新はバージョン番号が4から5になる大規模なもので、全エントリデータの書き換えが行われる「Remediation」というアップデートに該当します。
  • このバージョンアップで、電子顕微鏡の実験手法に関する多くの項目の書式が改定されました(例：em_softwareなど)。
  • EM NavigatorとYorodumiでも、この改定に基づいた表示内容になります。

外部リンク:wwPDB Remediation / OneDepデータ基準に準拠した、より強化された内容のモデル構造ファイルが、PDBアーカイブで公開されました。

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万見 (Yorodumi)

幾万の構造データを、幾万の視点から

  • 万見(Yorodumi)は、EMDB/PDB/SASBDBなどの構造データを閲覧するためのページです。
  • EM Navigatorの詳細ページの後継、Omokage検索のフロントエンドも兼ねています。

関連情報:EMDB / PDB / SASBDB / 3つのデータバンクの比較 / 万見検索 / 2016年8月31日: 新しいEM Navigatorと万見 / 万見文献 / Jmol/JSmol / 機能・相同性情報 / 新しいEM Navigatorと万見の変更点

他の情報も見る