EMDB-60633: In situ structure of the central apparatus in mouse sperm axoneme.

Basic information

Entry

Database: EMDB / ID: EMD-60633

• Title: In situ structure of the central apparatus in mouse sperm axoneme.

Sample

• Cell: mouse sperm
  • Protein or peptide: x 45 types

• Keywords: microtubules / axoneme / sperm / filament / PROTEIN TRANSPORT

Function / homology

Function:

substrate-dependent cell migration, cell attachment to substrate / cell motility in response to calcium ion / intramanchette transport / maintenance of cell number / axonemal central pair projection / regulation of establishment of planar polarity / axonemal central apparatus / regulation of cilium beat frequency / male germ-line stem cell population maintenance / respiratory system development / positive regulation of fertilization / lateral wall of outer hair cell / mucociliary clearance / axonemal microtubule doublet inner sheath / Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane / Cilium Assembly / Sealing of the nuclear envelope (NE) by ESCRT-III / axonemal central apparatus assembly / sperm flagellum assembly / radial spoke / manchette assembly / axonemal B tubule inner sheath / CaMK IV-mediated phosphorylation of CREB / Cam-PDE 1 activation / CREB1 phosphorylation through the activation of CaMKII/CaMKK/CaMKIV cascasde / Glycogen breakdown (glycogenolysis) / Activation of RAC1 downstream of NMDARs / Reduction of cytosolic Ca++ levels / Sodium/Calcium exchangers / Activation of Ca-permeable Kainate Receptor / positive regulation of flagellated sperm motility / Intraflagellar transport / manchette / Carboxyterminal post-translational modifications of tubulin / regulation of flagellated sperm motility / Synthesis of IP3 and IP4 in the cytosol / CLEC7A (Dectin-1) induces NFAT activation / RHO GTPases activate PAKs / Calmodulin induced events / Inactivation, recovery and regulation of the phototransduction cascade / Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation / eNOS activation / Ion transport by P-type ATPases / sperm axoneme assembly / protein polyglutamylation / trachea development / outer dynein arm / beta-adrenergic-receptor kinase / positive regulation of feeding behavior / Calcineurin activates NFAT / COPI-independent Golgi-to-ER retrograde traffic / Unblocking of NMDA receptors, glutamate binding and activation / Protein methylation / olfactory behavior / HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand / beta-adrenergic receptor kinase activity / cerebrospinal fluid circulation / sperm principal piece / G protein-coupled receptor kinase activity / regulation of cilium beat frequency involved in ciliary motility / Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal / epithelial cilium movement involved in extracellular fluid movement / RAF activation / microtubule anchoring at centrosome / cilium movement involved in cell motility / response to odorant / COPI-mediated anterograde transport / VEGFR2 mediated vascular permeability / Aggrephagy / sperm head-tail coupling apparatus / RAS processing / Kinesins / 9+2 motile cilium / metaphase chromosome alignment / PTW/PP1 phosphatase complex / G alpha (s) signalling events / Mitotic Prometaphase / EML4 and NUDC in mitotic spindle formation / acrosomal membrane / microtubule sliding / Resolution of Sister Chromatid Cohesion / PKR-mediated signaling / The role of GTSE1 in G2/M progression after G2 checkpoint / cilium movement / FCERI mediated Ca+2 mobilization / Ca2+ pathway / RHO GTPases activate IQGAPs / Recycling pathway of L1 / axoneme assembly / motile cilium assembly / Extra-nuclear estrogen signaling / RAF/MAP kinase cascade / regulation of nucleocytoplasmic transport / COPI-dependent Golgi-to-ER retrograde traffic / PKA activation / RHO GTPases Activate Formins / axonemal microtubule / Separation of Sister Chromatids / cilium organization / Hedgehog 'off' state

Domain/homology:

Germ cell-less protein-like / : / : / DLEC1 sixth Ig-like domain / Microtubule-associated protein 1B N-terminal / CFAP74 second Ig-like domain / Microtubule associated protein 1 / : / Kinesin-like protein KIF9 domain / Hydin adenylate kinase-like domain / Hydin Adenylate kinase-like domain / Sperm-associated antigen 17 / Cilia- and flagella-associated protein 54 / Domain of unknown function DUF4456 / Domain of unknown function DUF4455 / Primary ciliary dyskinesia protein 1 / MYCBP-associated protein / Flagellar C1a complex subunit C1a-32 / Deleted in lung and esophageal cancer protein 1 / Cilia- and flagella-associated protein 99 / Cilia- and flagella-associated protein 46 / Protein FAM228 / Leucine-rich repeat-containing protein 72 / : / : / : / : / : / : / : / : / : / : / : / : / : / Domain of unknown function (DUF4455) / Domain of unknown function (DUF4456) / MYCBP-associated protein family / Flagellar C1a complex subunit C1a-32 / Cilia- and flagella-associated protein 54 / Flagellar-associated PapD-like / Cilia- and flagella-associated protein 69, ARM repeat / CPC1/SPEF2 domain D5 / Deleted in lung and esophageal cancer protein 1 Ig domain / SPEF2 C-terminal domain / Cilia- and flagella-associated protein 65-like, Ig-like domain / Cilia- and flagella-associated protein 47 domain / CFAP74 third Ig-like domain / CFAP74 forth Ig-like domain / Cilia- and flagella-associated protein 65-like, Ig-like domain / : / : / Hydrocephalus-inducing-like / : / HYDIN/CFA65/VesB-like, Ig-like domain / CFAP74 first Ig-like domain / CH-like domain in sperm protein / CH-like domain in sperm protein / CFAP65, fourth Ig-like domain / : / : / : / Sperm acrosome-associated protein 9 / Sperm acrosome-associated protein 9 / Sdc1/DPY30 / Dpy-30 motif / Dpy-30 motif / Possible plasma membrane-binding motif in junctophilins, PIP-5-kinases and protein kinases. / CFA20 domain / Cilia- and flagella-associated protein 20/CFAP20DC / CFA20 domain / GPCR kinase / Serine-threonine protein phosphatase, N-terminal / : / Serine-threonine protein phosphatase N-terminal domain / MORN motif / MORN repeat / PapD-like superfamily / Adenylate kinase / : / MYND finger / Zinc finger MYND-type signature. / Zinc finger, MYND-type / Zinc finger MYND-type profile. / Regulator of G protein signaling domain / Aspartate/other aminotransferase / RGS domain / RGS domain profile. / Regulator of G protein signalling domain / RGS domain superfamily / Serine/threonine specific protein phosphatases signature. / Protein phosphatase 2A homologues, catalytic domain. / Kinesin-like protein / Leucine-rich repeat / IQ calmodulin-binding motif / Ankyrin repeats (many copies) / Serine/threonine-specific protein phosphatase/bis(5-nucleosyl)-tetraphosphatase / : / Leucine-rich repeat region

Component:

Cilia and flagella-associated protein 47 / Cilia and flagella associated protein 99 / Leucine rich repeat containing 72 / MORN repeat containing 2 / Cilia- and flagella-associated protein 221 / Cilia- and flagella-associated protein 70 / Cilia and flagella associated protein 46 / Deleted in lung and esophageal cancer 1 / Coiled-coil domain containing 180 / Tubulin alpha-3 chain / Calmodulin-1 / Serine/threonine-protein phosphatase PP1-gamma catalytic subunit / Tubulin beta-4B chain / Cilia- and flagella-associated protein 74 / G protein-coupled receptor kinase 3 / Cilia- and flagella-associated protein 65 / Leucine-rich repeat-containing protein 43 / Protein FAM228B / Sperm-associated antigen 17 / MYCBP-associated protein / Cilia- and flagella-associated protein 119 / Sperm acrosome-associated protein 9 / Putative aspartate aminotransferase, cytoplasmic 2 / Hydrocephalus-inducing protein / Cilia- and flagella-associated protein 69 / Cilia- and flagella-associated protein 20 / Microtubule-associated protein 1S / Leucine-rich repeat and death domain-containing protein 1 / Ankyrin repeat and MYND domain-containing protein 1 / Cilia- and flagella-associated protein 54 / Sperm flagellar protein 2 / Spermatogenesis-associated protein 4 / Sperm-associated antigen 16 protein / Germ cell-less protein-like 1 / Protein dpy-30 homolog / Spermatogenesis-associated protein 17 / Leucine-rich repeat and guanylate kinase domain-containing protein / Sperm-associated antigen 6 / Kinesin-like protein KIF9

• Biological species: Mus musculus (house mouse)
• Method: subtomogram averaging / cryo EM / Resolution: 7.7 Å
• Authors: Zhu Y / Yin G / Sun F

Funding support

China, 1 items

Organization	Grant number	Country
National Natural Science Foundation of China (NSFC)	31925026	China

• Citation: Journal: To Be Published; Title: Cryo-EM structure of the native central apparatus in mouse sperm axoneme; Authors: Zhu Y / Yin GL / Sun F

History

Deposition	Jun 23, 2024	-
Header (metadata) release	Jun 4, 2025	-
Map release	Jun 4, 2025	-
Update	Jun 4, 2025	-
Current status	Jun 4, 2025	Processing site: PDBc / Status: Released

Map

• File: Download / File: emd_60633.map.gz / Format: CCP4 / Size: 178 MB / Type: IMAGE STORED AS FLOATING POINT NUMBER (4 BYTES)
• Voxel size: X=Y=Z: 2.64 Å

Density

Contour Level	By AUTHOR: 0.004
Minimum - Maximum	0.0 - 0.01931374
Average (Standard dev.)	0.00077316083 (±0.0019510359)

• Symmetry: Space group: 1

Details

EMDB XML:

Map geometry	Axis order X Y Z Origin 0 0 0 Dimensions 360 360 360 Spacing 360 360 360
Cell	A=B=C: 950.4 Å α=β=γ: 90.0 °

Supplemental data

Sample components

Entire : mouse sperm

• Entire: Name: mouse sperm

Components

• Cell: mouse sperm
  • Protein or peptide: Spermatogenesis-associated protein 4
  • Protein or peptide: Kinesin-like protein KIF9
  • Protein or peptide: Cilia- and flagella-associated protein 65
  • Protein or peptide: Cilia- and flagella-associated protein 70
  • Protein or peptide: Protein FAM228B
  • Protein or peptide: Cilia- and flagella-associated protein 20
  • Protein or peptide: MYCBP-associated protein
  • Protein or peptide: Cilia and flagella associated protein 46
  • Protein or peptide: Cilia- and flagella-associated protein 74
  • Protein or peptide: Coiled-coil domain containing 180
  • Protein or peptide: Cilia- and flagella-associated protein 54
  • Protein or peptide: Cilia- and flagella-associated protein 221
  • Protein or peptide: Leucine rich repeat containing 72
  • Protein or peptide: Deleted in lung and esophageal cancer 1
  • Protein or peptide: Sperm-associated antigen 16 protein
  • Protein or peptide: Sperm-associated antigen 17
  • Protein or peptide: Tubulin beta-4B chain
  • Protein or peptide: Tubulin alpha-3 chain
  • Protein or peptide: Sperm-associated antigen 6
  • Protein or peptide: Calmodulin-1
  • Protein or peptide: Cilia- and flagella-associated protein 69
  • Protein or peptide: Sperm acrosome-associated protein 9
  • Protein or peptide: Protein dpy-30 homolog
  • Protein or peptide: Unknown1
  • Protein or peptide: Spermatogenesis-associated protein 17
  • Protein or peptide: Cilia- and flagella-associated protein 119
  • Protein or peptide: MORN repeat containing 2
  • Protein or peptide: Unknown2
  • Protein or peptide: Unknown3
  • Protein or peptide: Unknown4
  • Protein or peptide: Unknown5
  • Protein or peptide: Unknown6
  • Protein or peptide: Cilia and flagella-associated protein 47
  • Protein or peptide: Hydrocephalus-inducing protein
  • Protein or peptide: Germ cell-less protein-like 1
  • Protein or peptide: Sperm flagellar protein 2
  • Protein or peptide: Leucine-rich repeat and guanylate kinase domain-containing protein
  • Protein or peptide: Putative aspartate aminotransferase, cytoplasmic 2
  • Protein or peptide: Leucine-rich repeat and death domain-containing protein 1
  • Protein or peptide: G protein-coupled receptor kinase 3
  • Protein or peptide: Serine/threonine-protein phosphatase PP1-gamma catalytic subunit
  • Protein or peptide: Microtubule-associated protein 1S
  • Protein or peptide: Cilia and flagella associated protein 99
  • Protein or peptide: Ankyrin repeat and MYND domain-containing protein 1
  • Protein or peptide: Leucine-rich repeat-containing protein 43

Supramolecule #1: mouse sperm

• Supramolecule: Name: mouse sperm / type: cell / ID: 1 / Parent: 0 / Macromolecule list: all
• Source (natural): Organism: Mus musculus (house mouse)

Macromolecule #1: Spermatogenesis-associated protein 4

• Macromolecule: Name: Spermatogenesis-associated protein 4 / type: protein_or_peptide / ID: 1 / Number of copies: 6 / Enantiomer: LEVO
• Source (natural): Organism: Mus musculus (house mouse)
• Molecular weight: Theoretical: 33.629938 KDa

Sequence

String:

MAAAGQAEEC LPLPAAESSK TSLPTPPAVP AGKKPKKCLV YPHPPRSSRL SRSVLRWLQG LDLSFFPRNV TRDFSNGYLV AEIFCIYYP WDLRLSSFEN GTSLKVKLDN WAQIEKFLAK KKFKLPKELI HGTIHCKAGV PEILIQEIYT LLTHQEIRSI Q DDLANFTD YIYQMRLPLV PRNTVSKSIK NNIRLSELLS NPNVLSNELK IEFLILLQML QRKLSRKLNP GWFDVKPTVG EI TIDRLPA HSYKRRYKSR GSKEKAAQPL SKSDNDGNAR KEIHVKQSGN PCENTENL

UniProtKB: Spermatogenesis-associated protein 4

Macromolecule #2: Kinesin-like protein KIF9

• Macromolecule: Name: Kinesin-like protein KIF9 / type: protein_or_peptide / ID: 2 / Number of copies: 5 / Enantiomer: LEVO
• Source (natural): Organism: Mus musculus (house mouse)
• Molecular weight: Theoretical: 90.02307 KDa

Sequence

String:

MGTRKKVQAF VRVRPTDDFA HEMIKYGEDN KSIDIHLKKD TRRGVVNNQQ TDWSFKLDGV LHNASQDLVY ETVAKDAVSQ ALDGYNGTI MCYGQTGAGK TYTMTGATEN YKHRGILPRA LQQVFRMIEE RPTHAITVRV SYLEIYNENL FDLLSTLPYV G PSVTPMTI VENPQGIFIK GLSVHLTSQE EDAFSLLFEG ETNRIIASHT MNKNSSRSHC IFTIYMEAHS RTLSDEKYIT SK INLVDLA GSERLSKTGS EGRVLKEATY INKSLSFLEQ AIIALGDQNR DHVPFRQSKL THALKDSLGG NCNMVLVTNI YGE AAQLDE TLSSLRFASR MKLVTTEPAI NEKYDAERMV KNLEKELALL KQELAIHDSL SNRTLVNYDP MDEIQIAEIN SQVR RYLEG TLDEIDIINL RQIQEVFNQF RVVLSQQEQE VESALRRKYT LIDKNDFAAI SAVQKVGLMD IEGNLVGEPD GQSFG LGVA PFSVKPGKKP KTKKTPKDQF SSSARKEGAS SPVSGKDFDV ASISKTQLIP SSKDGDLKDM LARERETSSI EPLISD SPK EELRAPRPST PPSRTVAFEE FKNERGSEIN RIFKENKSIL NERKKRASET TQRINAIKQE IDETKDALNF QKSLREK QG EYENKGLMII DEEEFLLILK LKDLKKQYRN EYQELRDLRA EIQYCQRLVD QCRHRLLMEF DIWYNESFMI PEDVQVAL K LGSSIRPGMV PISRIVCLGE DDQDRFSHLQ QTVLPEGLDS ITFYNAKVKT DQKHNYMKTM VGLQQSHRK

UniProtKB: Kinesin-like protein KIF9

Macromolecule #3: Cilia- and flagella-associated protein 65

• Macromolecule: Name: Cilia- and flagella-associated protein 65 / type: protein_or_peptide / ID: 3 / Number of copies: 3 / Enantiomer: LEVO
• Source (natural): Organism: Mus musculus (house mouse)
• Molecular weight: Theoretical: 209.372391 KDa

Sequence

String:

MLIQKNQCHI TRTRENCDCT MNTVNEDLCL SASTLGSSSV TTQLVDPLDR KICLIRRQND VKKRVIWGIE VAEKLHWKGW ELGKETTRT LVLKNLSLKT QKMKYRPPKT KFFFTIIPQP IFLSPGITLT LPIVFRPLEA KEYTDQLWFE KEEGVFCVTL K ATLPCYKL DCPSSLQLPM CALGDTVETW FCLNNVGDLP TFFTWEVPAP FQILPTTGLL EPGLGCKIKV TFEPLIAVIH EV EALCWYG KGNKQKNSIN IQAAAKCAQL LVSIKHKGLE DQDQEGFQKV VHFGYVSVGS VAERQIRLYN PSAVNAPFKI EMA EHVLTK DPSFSCSTSQ GIVPPGEKKC LSLFFHPKTL DSRAIDYFSI IPSGCATKTL LQVVGFCRGP DAVLQHSCVN FHWV KLGER REQTLWIENQ SDCQAHFQFD IDCQESVFSI RPAFGTLAGK TRMTLHCAYQ PTHPIISFRR VACLIHHQDP LFLDL IGTC HSDSIKPAIL TPQHLTWYRT HLARGLTLYP PDILAAMLKE KKLERDEDGA LILPIESLPM QELEDLPDQK YPNIPP MTE YFFDGTRDLA IFPPAVCLEP IDVDFGACPG PEAPNPVPLC LRNYTKGKIT VVWTGRSDCP FWVTPVTSDV PPLKSIA LR LYFQPSSPNC LYAVELEAFA VYKVLQCYSN IEEDCTVVPS WCLKVRARGH SYSPALEHHI PHYSLDSPQT FPAVSPGK P SYRSLFLVNK GSMLMTFSLA PNSSSDITLR PSSGLIGPGA HQVFLISTYP KGTSWRQHIF YLNFNFYPQY LKEVSMQSR EEPLDLKLDT HKSIYFKPTW VGCSSTSNFT FHNPSRLPLQ FEWRVSQEHQ KVLAVQPSKG TIHPNENLTL TWIFSPLEEI KYLFRVGIW VWEARQSQKT KPQATVHYRI RLVGMGVTGC LSAKPVELDF GNVLVNSQEV KPLVLLNDGN CTLYYRLVLE Q HRPKGLHS DPCALEFDHS EGTMPPHSQD TIYLTARPKV RSQYSWTISY CLLSQRAPPT NSMDGKKKAL CHVSLAAAYP LL SVLDICS MGSTEGITRK HLWHLFSLDT LNSYLARDPT AKELTYKVPT RHSMSRTPPI FTPLKLDFNF GAAPHNALPS VVL LVLKNC GLVPLDWAFL FPSDQQLDLD LWVEQEDLNS NELHQMRAED NSLFSINPKT GSLNPGQEQM VEFTYRHLFV GTDR LSVLF KVSHGREILL QFIGVTVKLE QKYVHFTSTI HQFIPVPIGD TLPPRQIYEL YNGGSVPVTY EVQVSVLSKV QEKNF DHPI FCCLNPKGDI QPGTTARILW IFSPIEAKTY TVEVPIHIIG WNSAVVCFQG VGYDPCVMGD TAPFHSISSW DSSSIS SRL MVPGQNVFLS QSHISLGNIP VQSKCSRLFF LNNISKNETI VFTWKPRSLD FGEVTVSPME GEVGPEEGAP ILVTLKA SV HASFYSIDLI CKVYQRELMR QYHKELQEWN EEKARQEVEF TITDRKVKRR AYCAAHEPPK KYKTLPPITN QPPLNRPA T WNLKLAKKET SWPCPQPPVP GLLCLGLTAR AHATDYYLAN FFSEFPCHFL YRELPKKKSS KEESKSSEEL PDKKGPVSR QKQQLLVDCL TSIIRGLLED KNFHNAVDQN LVEQVPYFCQ FWNEQSARFL AQKSSLYLVP ILSLPPSYEG RKSKEQEEDL FGKMPGGQE DDEEEEEDEE EAEEEEEEIE EEMSKDEEDI DKDAKMTWSG IKVTETSQHS LQWQWQQDLK TIIKEETESD E KEAIGRLP AFANLQEAIL ENMIQNILVE ASRGEVVLTS RPRIIALPPV SMHRTDNLLQ MSQGDVLCSG MQHPDCLLVS AS SPSNMTT

UniProtKB: Cilia- and flagella-associated protein 65

Macromolecule #4: Cilia- and flagella-associated protein 70

• Macromolecule: Name: Cilia- and flagella-associated protein 70 / type: protein_or_peptide / ID: 4 / Number of copies: 6 / Enantiomer: LEVO
• Source (natural): Organism: Mus musculus (house mouse)
• Molecular weight: Theoretical: 128.422953 KDa

Sequence

String:

MDQTSSTTKI VHITVTNGYD LKGFKGDTPV TFVRAEFNQT VLGDSSKVTV SPEGTAKYNF TSNIDLSPDG GGALDDLAHK PLFLTVTEV LPKEKKQKDE KTLILGQAVV DLLPLLEGEE SFETTVPLHP VPGSPLETPL PGSKQCSLDV KVFVAEPLLT P AQVSASNL LKVTLEAAYS VPESFIPVGP QQNYMVGLQV PSVGEKDYTM IFKNGNLKLG GEKEPVPRPK KWPIANILAP GA SNIPDEF IVGGPYEEEE GELNHPEDRE FRNQAECTKK RIVWDLESRC FLHPFAVASF QKRIADCRLW PVEITRVPLV VMP KAKPGK LEKIDDENQL SFHGVAYINM VPLLYPGVKK IRGAFHVYPY LDGTVFEKTK CLFSLFRDTG HHLVQNNKAG GLNS PLSKP LSKNLKEEKP GKDKDTEGRP RLGELQAPSI KSQSSDTPLE SEAPLSHNLE GQQYIEAGTY IVLEIQLEKA LVPKR MPEE LARRVKEMIP PRPPLTRRTG GAQKAVSDYH TQIKSISRAI LNEYYRMFGK QGPKLESDID NETMEERKCQ LNYELN CSG KYFAFKEQLK HAVVKIVREK YLKTTAFESQ EELQTFISEL YVFLVDQMHV ALNQAVPDDV PSSTSTIQTS SEQLRLF AF EAEVNEKFEI AAMYYEERLV REPQNLENWL DYGAFCLLTE DNIKAQECFR KALSLNESHV DSLLLCGVLA ILLENYEQ A EIFFEDATCL EPTNVIAWTL LGLFYEIQNN DIRMEMAFHE AFKQLQARTL QTKLKSTVTI ENMEEGVKVE PSFGPWGVV QESTTAIKTE GLSGMRPQSS HQLSPHTNME LHPQPQGPNT ALSSLDEFLE ESPKAQSESQ EPMATGQPLE PSLVQRSSNA LLKELTSKK DISKCQDSSA FSPPTQHVIA QPPVTIFMET IRFLMKVNAV QFVHRVLAHE LLCPQGGPSC EYYLVLAQTH L LKKDFAKT EEYLQQAAQM DYLNPNVWGV KGHLYFLSGN HAEAKECYER TISFVVDASE MHFIFLRLGH IYLEEKEYEN AK RTYMHAC KRSPSCLTWL GLGIACYRLE ELTEAEDALS EANALNNCNA EVWAYLALVC LKVGRQLEAE QAYKYTIKLK LKD QALLEE IHTVQEMVGF GNPSF

UniProtKB: Cilia- and flagella-associated protein 70

Macromolecule #5: Protein FAM228B

• Macromolecule: Name: Protein FAM228B / type: protein_or_peptide / ID: 5 / Number of copies: 3 / Enantiomer: LEVO
• Source (natural): Organism: Mus musculus (house mouse)
• Molecular weight: Theoretical: 27.875152 KDa

Sequence

String:

MTTMKNRSQD DMVTGTLPKL KSSKEWLEPQ SLSFMEALAK EDTDAAVQSI LYRENYIMKE LDKYLHHQDF LNTRRKEMLY KKWVERVAD PLQKKIIEKV HSHKNIKKRR RQELDNFLKH SNKKGNAFIE HYDPKEYDPF YMSKEDPNFL KVIMPPFRDP L KKAQYDQD DEKRTLLQCE TGKIYTMKEF KEIEKAQLHS RFPSISNSRQ SMTPNGWLKV PMSYIESEFC KKSR

UniProtKB: Protein FAM228B

Macromolecule #6: Cilia- and flagella-associated protein 20

• Macromolecule: Name: Cilia- and flagella-associated protein 20 / type: protein_or_peptide / ID: 6 / Number of copies: 2 / Enantiomer: LEVO
• Source (natural): Organism: Mus musculus (house mouse)
• Molecular weight: Theoretical: 22.781389 KDa

Sequence

String:

MFKNTFQSGF LSILYSIGSK PLQIWDKKVR NGHIKRITDN DIQSLVLEIE GTNVSTTYIT CPADPKKTLG IKLPFLVMII KNLKKYFTF EVQVLDDKNV RRRFRASNYQ STTRVKPFIC TMPMRLDDGW NQIQFNLSDF TRRAYGTNYI ETLRVQIHAN C RIRRVYFS DRLYSEDELP AEFKLYLPVQ NKAKQ

UniProtKB: Cilia- and flagella-associated protein 20

Macromolecule #7: MYCBP-associated protein

• Macromolecule: Name: MYCBP-associated protein / type: protein_or_peptide / ID: 7 / Number of copies: 2 / Enantiomer: LEVO
• Source (natural): Organism: Mus musculus (house mouse)
• Molecular weight: Theoretical: 106.611914 KDa

Sequence

String:

MMKKITERQS PLKLLEKKRA KAPEQPTPPI QEEPEPVSNV LQGDDILALA IKKEDLRKQH VPQFEETGEK PVVTQKFIIR KLKPKDSSK RVYHLVAHPA TPDAATKPLD YSGPHDSFLS SGQILPHQIL GSLQDFKRIA VARGNTQLAK LIHIQPCLMT L ISAKEEPK PKPPKEEERP SPWAPPPQHN FLKNWRRHIA LRKKQQEALS KHLKKPASEL LMHTGESYRK IQEEREVIDR AL PTQHDGK ATSWFWSPLE YLGDEMTGLL MTKKKTQRGL VEPITHIRKP LSIQVETGLP AQKDAWYRYT WDRSLFLIYR RKE LQSIMA ELDFSQQDID GLEVVGHGKP FSSVTVEEHL PPEKIQKSSS EDTVFLDSLT NLSDMVPMPI LGPSLLFCGK PACW VRGSN PEDKKNIGIG VRLTFETLEG ERTSSELTVV NNGTVAIWYN WRRRPHQDFF QDLKQNKTQR FYFNNREGVI LPGET KHFT FFFKSLNAGI FRESWEFGTH PTLLGGAVLQ VTLHAISLTQ DIFMDERKLL ETKLAAHEAI TIAQSVLQDL LRGIST PER TPSPVDAYLT EEDLFNYRNP RLHYQHQVVQ NLHQLWQQYR KAKATQKETP SLRTPVPLLL VEKASGSISP RNLVSEY SQ LSPHQEMDTA RKTRDFFLSL KSSIGKKSVA RKSIMEELLV EEGPDRETTQ RPWALKSISP PKWNLCLEDF RQAVMTFP E ELQREDALIQ LNKAAMELCQ EQKPLQSDLL YQMCLQLWRD VIDSLVSQSL WLRNLLGLPE KETVYLDLPD EQGQKSPPV TESKVTSGKA GKEDRRGGAQ EKKQLGTKDK DDKRGSKTPG KEDRPNSKKL KPKDDKKVVK SASRDRLLSE DPPPDSTAPS QEPIDPLVM EKYTQRLHAE VYALLDNLVT DVMVLADELS STKNVEESLR FCS

UniProtKB: MYCBP-associated protein

Macromolecule #8: Cilia and flagella associated protein 46

• Macromolecule: Name: Cilia and flagella associated protein 46 / type: protein_or_peptide / ID: 8 / Number of copies: 2 / Enantiomer: LEVO
• Source (natural): Organism: Mus musculus (house mouse)
• Molecular weight: Theoretical: 302.995875 KDa

Sequence

String:

MDLIITQELA RARNQQDATA LRRAYELIKS ANLGKSELDP TESFSPDLFV LCAEQALKMK EPEISEDCIQ MYFKVKAPIT QFLGRAHLC RAQLCAPQSE ENVEEFENCV TQYMKAINFA KGEPRYYFLV FNASVLYWNM VRPFLKPGYH HLVIPSLSQI I TVLNQTEE EDKEWRAELM LELLECYLQA GRKEDATKFC LTAAPFVRTQ VPHKYRQMFS TMVRYEVLDD LMLREDKQQS II LSITYHI NSLKAKLDKN NLPENLEQIL RKMYRDLSQY HDQHVPTIRE EKILLLFELG RLCLTLKNEP IASDCLQYLK KME TEDTGK LLEMEGLECE LDALRLGSKL KMYLRGAVEE QLLIIKRMDN ILQRAIRLGN PTTIHVLCTA QWNICLPLLQ HNLR HHLRK PLTNIAEILE KVDSLMILLR CQVHMEMAYI EQDDDRVEPA IEHMQKAMRL DSLGIYRDKI KITYRRLQLG TMLYQ SPDR PEDKATMAIE QAKKATPKDS ARKKRAILVN AGLALAPDTF QIVLDSENES KVSIGKIKGR FTYLCAKARH HILSVD KAA GHLRRLGYEN DKDRIVIWAE LAKVAWQQDV WDVCRTASRF CLLYDNVKAK RSTKLKRGRK KKVIEGSMSD WAPSDMA MH KQMPPDLLRK IAKVLFISAE ATVHLLRSEG VQLNNQAIPP EDLSQHPAGY VPEPPESNSE WITYRTWIEN LSQYAMNN W MRAAEIGQEL GESWIVQNAV VYVLNHNRHL ILAGRQKELV ESLFHFLSII KIVGYTEDSV MLVMLCNALA RGLIMSWIP TQTPEKSKKN VRPTLVHGPL ESSTLSDIRA AVEVCEFALN LTNGNVPEDI VPTNVRQHLI ATWVKAKQLL QQQIGQRLGT DEQSTNEDI SSVTRVLVAL EMYSCNGLGL MDFTVPPLVQ VVKMASECNW SDHLVELQTL TRLTHFAYMA HDHEVTMACS Q NATQMGLK HLRSFEPSNA KLAAEMLCMV SCIQGRSIME NLKGRKQLRL AAAKAFVESA RFGGLANSNS LVMMAARHYW NT WLPLLSS PANRKKAKAS LQRIISIINK TENKKQETDK TLPLHQWPSA DFQTGGTGPE IPFLPGAEDD LTLRAALYTL LFN SHADRN DWEMGLKVLD EAVQVLPRTA HRLLIFKHMV IVKAKLGQNF TMEIQKFKDE KESYLASMWY RLAQNSKTVC GELS CYQNA IQALQKPENN WQKVDYIMEF SEWMYYKQFP LDDVFDHLDW AIEILLSMKP NEDALEPEPK KEGQASPAQS LTEST VPSN QTASLDQFRS VRQLEALARV HILRALMASP SASSYEDDCL MAYSFFKHIL QISLTEGVKL IPEKNLQAVS SQLLLT KKE KEKEKEKEKE REKKEKEKKE KKEKKEEKKE EKKEEKKEEK EEKEEKKEEK KEEKKEKEEE KEKKEKEKKE KEKEKKE KE KEREKEKVKD TKQISTSASN KPPDEIPTSI GEWASYSCSE DLLHVFKQDK SDCTINSSSF QKPTYSLYYI DHLAKALQ K MFLHELSIPI LQLGVLIAEA VVESKSLADL YHLRLLQVCS DLRLHYAATH HEEVIGQAYF GDMEQASCRK EIAFKKEKN KEPEMEDYLP TLHEQLTLSD SVEVKALIAQ DKILKINGET GKGLEGTSYP QLWLLKGEVL LELELHQPAR LLLSEAQWAF QELGDICSE AQSLLLLAEL ANKEKNHAQA MLMVERAQQL GGAEEFWYKS TLTLAEAILS SEDRRKEISV CSLFQKLIDT F RALQNERP NRVSLLEFLI MELEARCVKL RIQFACNLTD EEFNEHPFLL RELEDHLLEV EQNLIFGGYY KNYVDLKLDH AK IKRLCAQ KEKDEEQKTA YYLEMYSLSQ KAVSEEEEVF HRIQALLSLH DLQNINSPVM RRLARLKLSL AETCLDLLQL VCK EALDLQ MEQGSFEKLL ADFLQNTTDY TSIGLQWFFL KRTLPHLVLT QLESLQPLCV GCTDIRAQLL ILAGKALHLL YVQT DPVYP SFCWEEELLV GTKKDSLRSL ETDTEDRSVE TSSSAVFKEA PKEQSRKAEG LKKRMVLARG FLAQTSEVLL QCIQT SLSN NLLDIVASAS IEMVECIGIL DPITTCQFLT LSQSCSTSEM MRKVLLTATK NTGSSQLAAL LQLHQRLRQQ DKMSTS LFA SVEQKLASSF RAWQSLCVTE QHFSILNEIP PVFRILFLQH SQDRSCLYGA AFERPKTMPS PKGKLITVGG YCKVTRV AT SPTAISDLLT SIQWFQRQTR VKEQALCTQS LSSILEHMED YLKPITPQLT FPESRNQMPT AVGDAGKNKG REKERKIS L PSGQPDPEYL ILIVDKFLLE LPLEGLSMLN EVTSLSRDFS LQMLWNRLHK EEREGSMKKE VKSKDLKKKT PGKKALKSI MTRIIPPECN LIDSDTIKFV VDPYEEARGT ELMRPIEITQ EILEKYRDTF TGRWMGHLGN HNFPSQADWE QLLDSCRGFF FYGMETFLS HLEIERLVAM NLQECQMMIL LDLTRSSHSQ KRTIESSEGQ SASQRSLVKP IQTAILLSLV GVESIVDNQW P TLMQDNML RATILWDNLL AIGKPLGKTV RLIHKLCNEP GSQDEKPQVS KNEPLSELQP HHPESLTTAL NWVLYGLPHQ AI V

UniProtKB: Cilia and flagella associated protein 46

Macromolecule #9: Cilia- and flagella-associated protein 74

• Macromolecule: Name: Cilia- and flagella-associated protein 74 / type: protein_or_peptide / ID: 9 / Number of copies: 3 / Enantiomer: LEVO
• Source (natural): Organism: Mus musculus (house mouse)
• Molecular weight: Theoretical: 179.171109 KDa

Sequence

String:

MEEPTVQFSD EDLVDNFPPM DDERVQLEDL EFEVERPSEG LEDEGSHSSA KKESKGAEKM RKSTTKDQVQ AFHLRKSLNL LDKMHEEKD VFIQKTKGEL HICRQRMDLL NKQQESLAAE IATEKEANNM AAIGRLQAAS RRLQTELENE KDLQSKITAM L KDSENAMW HIEIQKGQFE DVRKHHEAEA EARQRGLEVH SARQLQRERE AMEKSEKNRL LRARKSLHTQ KELGLRHQKL VE DAQRNHR IAVKFLKASL GRVREREQKE EMESRTHMQR RMDAVLSLKN NITASRETLK KFQAWGQTRA DLAKQKALTE KEV ILSQGG DAFKYLFHQR RHQELEAQKR AFEEEQKLRK QEIVNRILKE EAEEEQRKRR QHPLSKPINR RTLRDKTWQY ISDF CEGKS VLTSQQERER ELLLYPKTVC VIKAISSESV QVDLGSISTE DEVLAEPDIS GLWNKESYQV PKEDMERKPV GGSKM EKDI LARTMEQLRS GVVQKQVVSG REFKGRPFNS KPEVIHFKDF DIGKVYKKKI TLINATYTIN YCKLVGVEEN LKDFIH IDF EPPGPMSAGM SCEVLVTFKP MINKDLEGNV SFLAQTGSFS VPLKCSTKKC SLSLDKELID FGTYVVGETT SRIITLT NV GGLGTKFKFL PDSEFYEMDE SQPAMKISSL FTCEEKIIYE KIMTSLSEQQ LEVNDSSLVD LQSLKESEKQ LDDPEVTT A AVSAMTMIPS EEQAEITLGE VTEGEIGPFS SVKVPITFTP VIPGEVQTKF KVMFKNPQSP PLYFRATGTA IDVPVWVPK ATVDLKICMY DRLYQDSITV HTRSKAALRL KFEVCKELRG HIELLPETGY IQAQSTYSVQ LKFLPRQSLP EDARKYFDPA SRVLEAPMT IRVADQIKPV RFTVQAIVTT SDLEINPSEI NFGYCTIYEA IRTEICLSNL SLLPQEFGFV GLPKYVDIQP N DGFGTILP LETLHLDVIF QPIKAKEYKF ELVCKSEINR CFKVSCQAVG VHPPLELSHY QIKFSATSLY DTSVSTLYVI NS HLSMNKM IHSLPRIGSE EAAPVGPTSF EFLLPPNSPI TISPSVGTVL PGKRCLIQVA FQPVLPKEII YKEASQILNK EIE TKPVSQ KEIVQRKELW KQSFSVVRVH NRDRPTRVST PQATELQRPV INSSSTEFQI AQATLSKAFQ GKFNRFVIPC VVAS GDIKD RKTAEPLSFS PHNTLYLELW CPAVAPFIVV TSHKGKTDFN FGDIAVGHRS VKKITLQNIC NEDLTLEYSV LNPNG PFVR LNPFNKLRSG ETQTLVLSFS PHENILAQET LDIITKRGTL SLTLFGMGVA SMITCSIDGN ILNMGYVLAR ESVSTN FKL QNESSLPIKF WVRLESLSRK KAEAHQQLPK FITSHEQRAE IVGTQNYNGQ SVFSIVPVEG LMFPGKAQEF TVTFSPD HE SLFFSDLLKV VLFEKKVSHQ ILLKGAAREH MMFVEGGDPL DVPVESLAVV TAFDTEHKEE AEELKPILVT LNYVQLDT D TTTSPATREL QVGCIRTTQP SPRRPDHPLM VSTLLQLRGD VKETYKVTFV AHVVTGL

UniProtKB: Cilia- and flagella-associated protein 74

Macromolecule #10: Coiled-coil domain containing 180

• Macromolecule: Name: Coiled-coil domain containing 180 / type: protein_or_peptide / ID: 10 / Number of copies: 2 / Enantiomer: LEVO
• Source (natural): Organism: Mus musculus (house mouse)
• Molecular weight: Theoretical: 196.116328 KDa

Sequence

String:

MREPPGLERR GIGPAVKMSP VGKVSQVQNG KVYQQIFQAQ VQLVQSLAAT RKQAAERSET QKNVKTPMMK KVPLPEGETM TPRQRKWVR SLPNDWVTEN PVLYREKEEA RKEKERLTDD MIASQEVQGL MDNIVPQLTE RVSNLQEQEE FKKRKYLSAL A SFQEELEQ IGVEMEPLIL EKGDLLLRKI SKSDEDVDML FKKVEGEPDL ESHTIETLLE LWEKVAERFM QQKQEIKELD EE LLALEVS RADKLKEVLK RYVGIIEKTS YILQPDVYRL IDKEAMAMNQ ALLGNRRAIA QLLVNLTEST LQQELDNRHR WQG LVDTWK ALKKEALIQS FSEFMASEEI QEPPEVKKKL EEMQKNQEML QSVRLDHLCT LCDLLPPNYN KTQLTEWYDS LTSL NKQLD TYHMDCMSLV HFLYEKIWQQ CLSHVQECKQ QLLNWKAFSE AEAESLVNPT FFLMVGEFQS KVEKQLELLD NSFED LARE TEWQSSDLFR YFQEAVKLWE GHQSVLMTQE LELEKRIEQH RQKHNQENQN QETLLDKLLD QLRQQSQEES LKAHME KAR TFLKNMKSRY ECFHLLLTKE VMEYPGLVLK ELNCYSFTLS RHFFIREIFE QNLSGEVIFK FRQPETHEKL FIQKIRK MK KKQRKRKGEE SIGQDLGSEK PTESMKEEGS GESEPSTAGE ALNQENKSPQ SDRVSEPRDG PSQEAEETLG VRETSSET S QDRENLKVQE EKEEIEEEEE EEEEEEEEEI KEERVEEEEK EEEEEEEEEI KEDEEEEDEY ENEDVLEYYQ ETYFMGQAE SREESDEIPY EEMEFFTTTS GNTYFAFLSV EDEQQIHSRP HSHHNLLNSF CTKYIEQVSI PQKLILKVKK GLRAGFFEHL EKWFDQCVL NARIIVASKV DELDSELELR LHLHKPRLEQ VEKDIHNVRA AELLLHQERL DSHCAGVIET LKKERLMFCQ F QEEQAVRS RNFRRKIYDM EHIFLNATRS QKLVSLTKTL HRELLSYVDV IQVSLRSFRQ YLEESLGKLR YTNIDFVKHC RL FSEGGNF SPEEVETLCH RLEKEATRIE FVESLIMIHM EKMETEYLDQ ANDVINKFES KFHNLSSDLI FVEKIQRLMT NLQ VNIKCQ EAKSNSQAEG LNSSLEQLQQ KIQTCQDHRG DKDIVTTDDL LAFVRSWKEK LSQRIKYLNC SLDMVSITQE VFTD TILAD TEVESDMHMS MEALEEDVKV GLVTPESFAQ PTRMGRPMIE DPAVDVVRRI LQISQAKSTC PCDKDRSQTA LKRRY RAEK ALKKALASAS VTSAGSMTRH PKYIRVDKKY QVLGEKPTSQ AEDFKGIILN LLWESNEHLM VVVEDFYRKE KRPVTR PEC MYESFDQCAD HISRKILEYH RQADEYHNSC LLELRAQVRR FEELLPQVCW LVTENYKEQH WGKFCASLKE VQEQFEQ QQ KQLELEKDEN ARKLHPNLGH PTYISQMESL QMAEELRQQE LNRMIHENQE KMEEFAKKYA RFFISNLASF TERFLMQL D EVITIDDIQV PRSEPPKQKV SILIRRKLAM LSLEEESEKP LIERGSRKWP GIKPNEITIQ NKILTRRTPS ITTNKTTLG HLAAIEARDA VYLKYLALFD KELKGIQDHF RKLLLESQRW KESWKRSLST IQTLYSTCSP LQLK

UniProtKB: Coiled-coil domain containing 180

Macromolecule #11: Cilia- and flagella-associated protein 54

• Macromolecule: Name: Cilia- and flagella-associated protein 54 / type: protein_or_peptide / ID: 11 / Number of copies: 2 / Enantiomer: LEVO
• Source (natural): Organism: Mus musculus (house mouse)
• Molecular weight: Theoretical: 354.209125 KDa

Sequence

String:

MASSRSSSSS SEESPDSETS VSPVHLPPTP PPTSTAVLKS PSESKSSSTD PPQCTHSEDS LPSAAFYGPL DSKNPLLASC EKEIRELLG FMKKKKALAT SMEQKYEFHR RCATTLFNIW TKYAPRLPSN YYNEKLLKVG DSLCQIKEYK LALLQCYGRY L QEFIADFD EHKEDVNHFK TVFFPKGFGD ETARLTFHAL SGKNICNYQL VCESDANLQN EESVRQCLHI LSSFRLIMQV AL PQEHLCW IIFNGTLYIY TICRKLMVIG QSSKALEFLL WASMCMESSV PLLSIRYLTW RATLYTAVCQ CHYDCQDGIH GEA FARRAL AKIDELRQLE LMSSSSSLET SRKYYREATI KMAVMIFKRG VFESRRKNKN VLRPKLRLNL KEAQSLPWPR TVTE RLLDE LLDSTSSRFL AVLEALSDSN RRILQTGPLV TDEMELRDVV SELFMAGKEL LILSNVRSNG KLDFPQTSLL EHVVE KRNA LSVGASVRFA KLAFTYEEWG LFESLAGQLI HFLQKQDNPQ SKKAEKDLIL LLAVEPLINV KRNRGLIFPL ETDKET QSI ENYLKHIACH ESCMRTTFTE DTFSLAAILH FCVCVPTQGV LPDKDIVVDI IGLLWQRCKL GIQRLNIPKN DFAKYSH KI STNKWVYLLW QISEVIHCYK LEDLDIVMVA EITLRLSEIL ESLGSPKRKF KKSADLSAKK GPDELPGTSK GVPEILPI L KRAPVEQLFY AYELLDKAII GMSWKCMLTT LSDGSSVIDH CYVKDSQDVD GDTYKPIASN SYTMDLHLEL IQAQHRIAV VLLDQLEVLQ APTVSTNTPA KGWEKVKKPR STECFTELTV MKKIKKNKLS KAIYLMQKAL LLFEKDAVCE TSRNLLMEAN ALIEKVEAE QNALYSYQKF LGSSKIKKSR IPPPPILLAR THCSVTLKPA PFISEVKASW YCILGCKADG SYGKVRLNNN H LPNSGEAI PADGRSFFEI KGLETNAQYC FAIAAYSSSG KLIGDAIGET TKPILIYPPL SAVTARMYLT QVAYQIGNYE MA KKVFSPV WDYFVASPLP DEQSVICLSN IMTITQKRLH SNILADTSSI LLYLFLRNIF VMSDIKIKEE NLFCDNIKGN EIF PAQQVA RLVECENVLV ALELSNFLND ANFALQAVTQ CYGLLAPIIY HNIVLVPVIQ ILIKCIVVLQ GIPSIIHSKK NISS FESIQ HMIACCIFYM TKILRSWKEY DLAIMLINYG KKMLDITSGC RSLFGIEQEE TAEEGVCSKK TSRTKKPQQV LLPEK INEQ LALLETHLLK TTKQINSAEL SGSEDPIFLY PIVLNWTVKG AMKEVMKFKQ RPRFLEFFTQ IMLKCMNDEK FHLMVE ISA PVYDFLKRRN ESLIGVKRIK YKETVISRRA LKSPSKFKAI VIEIGKSSDL TRRRRKKKKT LKDFFYKNPS IFDMAEL DR NKRTDVRKMA YRSLSDNLNP LILTYVRRKR FHQILLEELP WRAQMNLYLA NAHFHLFLQK LTERTKERLG SSYSSVSF R SCDPNLFSLF HSGTVLPTAK LTVDSYNAMM DALTVSKKKK HNQTTDTEDL SVLFNSKSDD NIPKMKTQTI YESDSQLGI GVNVREKDRT LVWGLDHFMK IFLCCRRAMV LAYRGGYWTL LQNCCRVFWN FSRELQILLK QTVASCKTFP VSQDNFLCIC VLPFYLGAE LLIDMLIKLQ STNSIKPFEE RGEFSIPSCY GNIKSDNGGS SLIFEHPLDD VNVVDLRWIH DFVLKSLEVL Y QVEKWETL VSLAIQFNII SHERYTEQVT PLLVYAQRQL VQRIKELNGP ELSRQACARY EAENGEKITC RNFIGKRLKI DS STPKNLA ELQGSSEPLK TLITSEQRLA KQLVSVPLDV NDTLRCFRET LEKSKYHNRS VRHSRKLLSL FLAQTQDVLQ TSN QRSLKV QSLHSLGSLL LFADKKRAAF KCWSQALDDI FRKPDVLHNW KEFGTSLPGA PSSSSPPGFK DYSEEFLSKF GIWG CLQAA MITAKIAQFI KTANVKKRIN CCILSALLFQ SLLRTTLPHP KAERNYAQYE ITQLLPGIEL FSDKFRADIC SVIAS LYYV IRELHYAKYN LIVLPLLALY QYFVSVICQD IVRNLEARIL KIEILIDLGF FSEAFYELFQ IYHGKNMPCA IPAGYK ATM KVKITQSFDS GKPLTHKDNM QALEELINRG LPHILVNLGY QHLLNKFNFA KSHFFISLAA TINCIPDPSP KIMYYQF IT ERSKPTPQNL KDNENSHGQF LRLRDDYNLN TIKSILLMEA EEKVNSLLSE TEHQCHRPLY LSSVLELEIM VEARLHLA A IALQRYRPAY STAILYSTLK LLQDSKVFKK KVPEESCSPT SPETSTTESK DDSEFLDPIS LNSREYFNIH LWLRCRLML VTSFIAQIRG IGIMKESELT DCLSLIDEVC TEAKSADDTE VLAEFLMQAV VLGLQEKHFK ADIIQKLKEI ISLLEGSEFL SPRSWLTLA KSLILMDDLT KAEKFKKASS KENKLIFLNQ AHRILIAQML TFGETIEFPL SDSDYASPLQ PLKNIYLPHV M LLAKVKLR IGHTMAKQVC SSSKKKDISK WLPVLHMFDM ALKVCKATAA EEYEVEAEIL FQKGRIERQM LMEEKTSIAH IE SFFEAIQ ISLKNDQNSG LIRDSYLEIA LVYFYLKKPK RKASATTLKP LPRRHSSVKD PVATQTEMYS SLAWIAIRAA AQV SESVLG INLLIGKKRA MIDKVNNITL PNIPEFATVD LLSSYTDYLL ENYQVVFQTS NSLMCENDDV YDCIDGRKRN LSKV DVTWI LLIRYYIHLQ RINNMSKLLA SATPVSGISL PDDTLLTSLY NSELILRQKE MHLFLKRFLQ LYSSSCIDGF PRELL QGLE NISLEKVLFE SSGKVHRDSS LQSDLSGKLT VCPSYTEISS EMAVQALNKE LCFQWYIPPL DKPLKDSEPM VLLLYA YNL KPLRILDIKV STGNSLYVGT SWIPLRSVIA VHQKLSNLAQ IAEISLPSVP EVTSEENIYE TIEPEDKPID TDLENMI LE CCSEIEALFS NNKDKDNEPP PPMTKVPFDV SLPAIFSLER LFDLANGCIV SVGSLFNWMV SIIQ

UniProtKB: Cilia- and flagella-associated protein 54

Macromolecule #12: Cilia- and flagella-associated protein 221

• Macromolecule: Name: Cilia- and flagella-associated protein 221 / type: protein_or_peptide / ID: 12 / Number of copies: 1 / Enantiomer: LEVO
• Source (natural): Organism: Mus musculus (house mouse)
• Molecular weight: Theoretical: 97.096742 KDa

Sequence

String:

MEVVKSPMQE LQQAKEPFDT MSPLLLKSLV EEPKKRTEVP NHLLESRVYA KLLNNKVIQA RPGIVHFGGY EIESKHQQIL NIANISDED THLHILPPQT KYFQINFEKK EHRLIPGLSL TVTITFSPDE WRYYYDCIRI HCKGDDTLLV PIHAYPVLNN L DFPTFINL SDVFLGESKS YVIPLQCSCP VDFEFHITLL RSHQAFTIEP KSGIIPANGK AKVTVKFTPI QYGMAQIKIQ LW ISQFNSQ PYECVFTGTC YPNMALPLEE FKRLNTRSKK VNVPLEKTTY VQFYPAPAKA KPQKLKEIDY QDLRFPADLS NPF AVATVL NQEPGKLKIK ELKQVLDQGD EISKTRQMKE AIFEQKVRQD ILTEIENHLK WQVHLGKEHT TYRFKRELTE EWKK ARAKY KQNRGDPVEG EELQRLQTEQ SQKRIVRDLK GKRQEFHPNF DPLVNNVWLT RHRAQRRFQQ AARKIMLERR LLSML GAIR GMDKESILRK IIQVNGKLIQ GENPSRGRRA HLKQEDNIWR YSLESEEVLH FAFPTDSESY NELALDGLGL VPIKSP EIQ IKHSYPYFTL KVPQLYKIKG YHPFSVNKSS TNYRLQKLAR PLKHGAEDEV TTIITIPKKD TTPLSAKPSI LSMKPPE GL AMSVEYDPLY IFNPSPGLFA VKHPLTYAET LIDYHLCSHP KYKYTQESHM GSSIPLTQRQ FLHHTDIIPG IMNWKKFQ P LVFSSMSDPS MVEATQRSDW YSSVMLPIDV PAPLEDLPEE DRLETTERDL CDQGIEVMLT PEMVQVEFPM LIHRDSKKE KDFKDSTQLP EKVGERVQEE MKNLRSKALN TYLILD

UniProtKB: Cilia- and flagella-associated protein 221

Macromolecule #13: Leucine rich repeat containing 72

• Macromolecule: Name: Leucine rich repeat containing 72 / type: protein_or_peptide / ID: 13 / Number of copies: 1 / Enantiomer: LEVO
• Source (natural): Organism: Mus musculus (house mouse)
• Molecular weight: Theoretical: 33.75927 KDa

Sequence

String:

MSRNRNSSSF VFPCTKVRKV SVENALPSSL KAVEDQLKIC GHKRDIDVLE LFLSKKELTE VIDLSRFKKL RYLWLHHNKL HGISFLTRN YCLTELYLNN NAIFEIEGLH NLPSLNILLL HHNELTNIDA TMKELKGMQN LRSLSLYQNP LSQYNLYRLY I IFHLPGLE LLDRKQITEK ERRYMITIFD HKKAHVIQSV AFGKRVDASW NPKLPIKQKR VKKPPSDFAF GDNVDKTLFD DP EDAVFVR STKRSLMTFT SMNWNTVLTR SEKYDQKKKS SAAEMLMISL R

UniProtKB: Leucine rich repeat containing 72

Macromolecule #14: Deleted in lung and esophageal cancer 1

• Macromolecule: Name: Deleted in lung and esophageal cancer 1 / type: protein_or_peptide / ID: 14 / Number of copies: 2 / Enantiomer: LEVO
• Source (natural): Organism: Mus musculus (house mouse)
• Molecular weight: Theoretical: 194.00275 KDa

Sequence

String:

MDSESKEEQQ CTASSAVMSS LETQFLSVPH QLESASLSWS IRKSLHSSTV LMDDCHFGFP TRSLRAGFHA LPPLPEPQTL RLRPASLRT QEISHLLARV FRNLYTAQVI GDDLSDSLIK ARGSEDARHE EFLDQLQQAR AIYKQRLDEA AMLERHIMQA R ARDIAETE HTTKQSRLQV VETPVKLPPV KTAFRWCLDS KLMRKHHLIS TEDYYTDPVP FCPAPKDKST LGCSKLTFSC EQ RFLRKSE LDREAEEHCR QLTECDDFEY TVDSLGSISK AKERTTDSVK KTSRPKNKKW MEHLQVPQRA LDRRLLASME NRN HFLKNP RFFPPNTPHG GKSLIVPLSK PERRASLNAE PEWSCTDAPV FLAKPSVGFF TDYEIGPVYE MVIALQNTTS TSRF LRVLP PSSPYFALGL GMFPGKGGIV APGMTCQYIV QFIPDCLGDF DDFILVETQS PHTLVIPLQA RRPPPVLTLS PVLDC GHCL IGGVKITKFI CKNVGFSVGK FCIMPQKSWP PPSFRAVATT GFVEQPPFGV MPSVFELAPG YAILLEVLFL PTGLGQ AEE TFIIVCDNCQ IKEVVVVGTG QLVALDLIHI SGGKNEPDPG ELKDLTAQYF IRFEPENVQS TAKKQLIIRN ATHVELA FH WQIMKPNLQP LMPGETHSSD SIKCHPDRET AFSIIPEKGI LESHSDQEFI LSFSPYKLKC FHSVLQMVLE AVPEPLSS G LENLGDYSYS VDDMIVLEIE VKGLAEPFQV LLEPYALIIP GENYIGITVK KDFKMWNNSK SPIRYMWGKI SHCHIIEVE PCTGVIEPNE VGDFELNLTG GVPGPTSQDL ECEIKDSPCP VVLHIEASFK GPALTIDVPA LQFGLLRLGK KASISIQIRN VSQLSAVWH LKESPVCLAE RDEDVSPFDI EPFCGQLLPL GECRVTITLE ASQCQRLQTV LELEVENGSG SYLPVYAEVQ Q PHVYLKNS HLEFSNLYLG VSTKSRTTLV NGTLLPTRFH WGKLLGPQAD LCTMTVSPTQ GLLGPSEELQ LTLELTTHTE EK LTNLVLL CHVSGMEKPL VLGISGKPLG LQVTISIVES DGSSTTSTTQ EELRLDFGSK VPLRTPVIRH IILTNCSPIQ TPF TLTLEY FGSSQDSLYK KTSVPDVPPA LLKTARIQQH VAKKERLDFV ESMLSHRKGA AFLPHISQGM LGAYQELCID ITGC ANMWG EYWDELLCVV GDLPVTVIPV YMAVVGCPIS SLRNTCYSVA PFQKEPITRF GTQISGGDTV TRSLRLYNSS HCDIR LDWE TYIPEEKADR LLELLVFYGP PFPLRDQDGS EIVCPETSEA SLPGSPCPSN VSVSSHTVPS TVSSGGGGGT RAEEQI MSV ILQRHEAVPA GHIYRISPKQ LVIPAGDHRT IYISFTPTVL DPGVMHKVGY TGYALGFMSL DKETDRQIPG RMRRLQD FA VSPLRLDLNG HVRHAQLHVE LDSSGYLEFW CQASDLIPQN PCSGVLSDRI TTRHLKLTNT TEILYDFQAR VSRPFFIS Q GGASWDSRAP HQCEEGTAST GQWLMIRPQD NMLVDVSFSL SLELLSYQKL SADQMLPGVD IQESENGERK MVFTQNLLL GFTNQTVQEV PLRAFVTLPA PQLSTSWVDF GTCLVNQQHT RQIYLMNLSC CLSYWTVLLG QEEPAREDHA FGVSPGSGLL EARATNAPP TSSPLQVFFN PRSSILYEST LVVEGVLSEK PCVLRLRGLG SYDERYVKFH EF

UniProtKB: Deleted in lung and esophageal cancer 1

Macromolecule #15: Sperm-associated antigen 16 protein

• Macromolecule: Name: Sperm-associated antigen 16 protein / type: protein_or_peptide / ID: 15 / Number of copies: 6 / Enantiomer: LEVO
• Source (natural): Organism: Mus musculus (house mouse)
• Molecular weight: Theoretical: 71.570812 KDa

Sequence

String:

MAAPSGVPPL RVLEELGIGL SPTGEVTEAV TSEGAYYLEQ VTITETSEDE CEYEEIPDDN FSIPEGEEDL EKAIHIIGEQ ARDIHILEQ QTILPARNVM QEAIEDFLCN FLIKMGMTRT LDCFQAEWYE LIQKKGSDFK GLGNVPDVYS QVMLLETENK N LKKELKHF KQAAEKAKED LLRTQKERDF HRMHHKRIVQ EKNKLIADLK GLKLHYASYE PTIRVLHEKH HALLKEKMLT SL ERDRAVG KISGLQATLK NIDMGHIQVP VIKGSYESAS ITRESGDRAG HSCEKENSSE GPTQKSLREA REEVGYKSKL KNE KKDSEF PVDMQPDPNV TSCTENVSAA KFDYKLNNIF RLHELPVSCI VMHPCRDYLI SCSEDRLWKM VGLPQGNVLL TGSG HTDWL SGCCFHPSGS KLATSSGDST IKLWDLNKGE CTLTLEGHNH AVWSCTWHSC GDFVASASLD MTSKIWDVNS ERCRY TLYG HTDSVNSIEF FPFSNILLTA SADKTLSVWD ARTGKCEQSL YGHMHSVNDA TFTPRGHIIA SCDARGVTKL WDFRKL IPI VSIDVGPSSG NEVNFDQSGR VLAQASANGI IHLLDLKSGQ IHKLVGHESE VHSVVFSHLG ENLYSGGSDG TIRLWI

UniProtKB: Sperm-associated antigen 16 protein

Macromolecule #16: Sperm-associated antigen 17

• Macromolecule: Name: Sperm-associated antigen 17 / type: protein_or_peptide / ID: 16 / Number of copies: 3 / Enantiomer: LEVO
• Source (natural): Organism: Mus musculus (house mouse)
• Molecular weight: Theoretical: 263.465531 KDa

Sequence

String:

MAPKKEKPTG SANYKIWEPS LIAAHLNQND WKASIAFVVG NRVEDDLLIH ALDLAVRLPQ RKLFSIVSWE DILQQMDEIQ SLAESASAK KGKKPTSVNL PLHYEVFLAA KIIMESGEKL TLPLIGKLLK CQLLHIKSKD QQRRENEKKM VEERTKSEKD K GKGKSPKE KKVASAKPGK GKSKDQPEAT VTVRKTTQLK RRGEDDEAKS YIDDEPDDGA QYYIIVVGFN NPQLLAIMTE LG IPITSVI KISSENYEPL QTHLAAVRQQ QEAVLQPEDI EAEKLKRKNS IKELEVFWKY LEPILNNEKL EIHLFDVARL QYM VKATYF PSDWSDNEQM LALGTEIFEN IACLMYDSLD WKRQHHHYLQ SMQLINVPQV VSEKTVLEAI TIPEPPPSTA PAPT GKKKA QYEESHAPPT VAFIITTEVD MRYYNDLLNP IPEEFISVSL ILHCMVEQVV ATEEDLIPPS LVEPAPRADG LDYRI AAHI VSILPSLCLS EKEKKNLREI FLTEGESESK ALPKGPLLLN YHDAHAHKKY ALKDQKNFDP VQVEQEMQSK LPLWEF LQF PLPPPWNSTK RLATIHELMH FCTNEVLSWN EVERAFKVFT FESLKLSEVD EEGRLKPTET TSDTDVENFN IPWDNPA RF AKLIRQRYIH RMSMQKAPPV VVEIENTERT LFVNKNFAKA EQDAQGDENS PNSDEPDAIS VTGSTSNSTK PWNSSNRQ F SEKETSGSMW PQPESMDQTM DTEIKDDAAT KDDSPEKKPK KMVVEADIED IKKTQQRSLM DWSFTEYFQP KVLLQVLQE AHQQYRCVDS YYHTQDNSLL LVFHNPMNLQ RLQCEHWNIA LHSNVGFRNY LELVAKSIED WVTQEEAKYQ EAKMAEELNR IRIELELKA TVKTSASKIP GPKRSKTNKV SSKTELSDQE KDKEKEKDKI PFVLEGSLKA WKEEQERLAE EERLKEEKKA E KKGKDTGK KKGKDKADKD DAKALKKKSS SKEKPKEEPA KTLEVIEETA PLPVPEVVYP FRGYNMGDIP IQISGTNYYL YP SDGGQIE VEKTRFERGS TFIKVKVKKD KHNFIIHLKD PKEIVKKEKE EKNSEEEEEE EEEKEEVEEK KPKEGEEEKV KQK VEMKRA QIEKEAVSKF GSFSATLENG ICLSISYYGS NGMAPEVINS ELEAMMNIPS AMTATVVPAV VTVPQGKGKA KPKG KEKHK DSIKEEELPK EEEKKNHIQE EVEPEIVIQE SPPYVPTFQN LNVSCPSGLL LTFIGQESTD YSIVDEEPTR NLMIR QSYP QRLKHYEFYK AVMPPLEQEA SRVVTSQGTV IKYMLDGSTQ ILFADGAVSS SPDSGPVYTS PELPTSPHNG DLVDSA SQP KSETGPEIII TKKGKGHKNQ TVANKSETHD IIPEVPPPTP VESHIGTWFT TTPDGRRIGT KGLEKIEDLK PYLFFQA TD PINGTVMTTR EDKVIIVEKK DGTRVVDHAD GTRITTFYQV YEDHITPSND EETTEGPRTV TRQVKCMRIE SSHYATII T NCEDSSCCAT FGDGTSIIAK PQGSYQVLPP NTGCLYIDKD CSATYCHESS NNLYHPFQKR EQLRASRYIM KHTSEVICE VQDPEGNTFQ VMADGSVSTT LPKKKLEDDF NVQMEGYESL SSLHLEKNHM QIYGEHVPRF FVVYTDGSGV ELLRDSDIEE YLSLAYGES TTVVLQEPVQ EYPGALSITV LRPFHEASQW IMKKELDTIV PPNLQSRSWE RFPSVEKKTP GPPFGTQIWK G LSIGSKQL TNIPAPILEG PKVLQMRQFI QHEVIKNEVK LKLQISLKDY INHILKKEDE LQEMTVKDSR TEEERGNAAD LL KLVMSFP KMEETTKSHM TKVAAHLTVL FKQSMASAPK CSPDSYSKEF LEKKWRSLSQ GTSWKEKLEQ QRNNIKKTQS YLM QIKTKE VTPYFKSELS SLFKSKYDYL EKFSKSLPPF VKKNEAKLMT AVPDLYSDST LTVDTEKEAS NTHPLLNQEV AENI QESPR EKETEYVNKS LQTSSSQNQY ENVTISPKES VYQSQTEIET KDTKESAIQN FTEKFKKYTK KSASQNEIED LIKST KESV SQRQTENVTR PPTEEPDIYM PIKIPTQSLL QDVTGQARKE KVRLPYYMMS SKPKSQPYAK VEDPVGGRVN TSSIAS AAM YNPNASPFGF HLLPPSVKFG VLKEGHTYAT IVKLKNVGVD FCRFRVKQPP PSTGLKVTYK PGPVAAGLQA ELKVELF AM AVGEDGAKGS AHISHNIEIM TEHDVLFLPV EATVLTSSNY DNRPKNLPQG KENPMVFRTS TISSSSLGVV MSQKATHH

UniProtKB: Sperm-associated antigen 17

Macromolecule #17: Tubulin beta-4B chain

• Macromolecule: Name: Tubulin beta-4B chain / type: protein_or_peptide / ID: 17 / Number of copies: 130 / Enantiomer: LEVO
• Source (natural): Organism: Mus musculus (house mouse)
• Molecular weight: Theoretical: 49.877824 KDa

Sequence

String:

MREIVHLQAG QCGNQIGAKF WEVISDEHGI DPTGTYHGDS DLQLERINVY YNEATGGKYV PRAVLVDLEP GTMDSVRSGP FGQIFRPDN FVFGQSGAGN NWAKGHYTEG AELVDSVLDV VRKEAESCDC LQGFQLTHSL GGGTGSGMGT LLISKIREEY P DRIMNTFS VVPSPKVSDT VVEPYNATLS VHQLVENTDE TYCIDNEALY DICFRTLKLT TPTYGDLNHL VSATMSGVTT CL RFPGQLN ADLRKLAVNM VPFPRLHFFM PGFAPLTSRG SQQYRALTVP ELTQQMFDAK NMMAACDPRH GRYLTVAAVF RGR MSMKEV DEQMLNVQNK NSSYFVEWIP NNVKTAVCDI PPRGLKMSAT FIGNSTAIQE LFKRISEQFT AMFRRKAFLH WYTG EGMDE MEFTEAESNM NDLVSEYQQY QDATAEEEGE FEEEAEEEVA

UniProtKB: Tubulin beta-4B chain

Macromolecule #18: Tubulin alpha-3 chain

• Macromolecule: Name: Tubulin alpha-3 chain / type: protein_or_peptide / ID: 18 / Number of copies: 130 / Enantiomer: LEVO; EC number: Hydrolases; Acting on acid anhydrides; Acting on GTP to facilitate cellular and subcellular movement
• Source (natural): Organism: Mus musculus (house mouse)
• Molecular weight: Theoretical: 50.012359 KDa

Sequence

String:

MRECISIHVG QAGVQIGNAC WELYCLEHGI QPDGQMPSDK TIGGGDDSFN TFFSETGAGK HVPRAVFVDL EPTVVDEVRT GTYRQLFHP EQLITGKEDA ANNYARGHYT IGKEIVDLVL DRIRKLADLC TGLQGFLIFH SFGGGTGSGF ASLLMERLSV D YGKKSKLE FAIYPAPQVS TAVVEPYNSI LTTHTTLEHS DCAFMVDNEA IYDICRRNLD IERPTYTNLN RLIGQIVSSI TA SLRFDGA LNVDLTEFQT NLVPYPRIHF PLATYAPVIS AEKAYHEQLS VAEITNACFE PANQMVKCDP RHGKYMACCM LYR GDVVPK DVNAAIATIK TKRTIQFVDW CPTGFKVGIN YQPPTVVPGG DLAKVQRAVC MLSNTTAIAE AWARLDHKFD LMYA KRAFV HWYVGEGMEE GEFSEAREDL AALEKDYEEV GVDSVEAEAE EGEEY

UniProtKB: Tubulin alpha-3 chain

Macromolecule #19: Sperm-associated antigen 6

• Macromolecule: Name: Sperm-associated antigen 6 / type: protein_or_peptide / ID: 19 / Number of copies: 27 / Enantiomer: LEVO
• Source (natural): Organism: Mus musculus (house mouse)
• Molecular weight: Theoretical: 55.329016 KDa

Sequence

String:

MSQRQVLQVF EQYQKARTQF VQMVAELATR PQNIETLQNA GVMSLLRPLL LDVVPTIQQT AALALGRLAN YNDDLAEAVV KGDILPQLV YSLAEQNRFY KKAAAFVLRA VGKHSPQLAQ AIVDCGALDT LVICLEDFDP GVKEAAAWAL GYIARHNTEL S QAVVDAGA IPLLVLCIQE PEIALKRIAA SALSDISKHS PELAQTVVDA GAIAHLAQMI LNPDAKLKRQ VLSALSQIAK HS VDLAEMV VEAEIFPVVL TCLKDKDEYV KKNACTLIRE IAKHTPELSQ LIVNAGGVAA VIDCIGSCKG NIRLPGIMML GYV AAHSEN LAMAVIISKG VPQLSICLSE EPEDHIKAAA AWALGQLGRH TPEHARAVAV TNTLPVLLSL YMSPESSEDL QLKS KKAIK NILQKCTYLP ALEPFLYDAP PNILKHVVGQ FSKVLPHDSK ARRLFVTSGG LKKVQEIKAE PGSLLQEYIN SINNC YPEE IVRYYSPGYS DTLLQRVDSY QPL

UniProtKB: Sperm-associated antigen 6

Macromolecule #20: Calmodulin-1

• Macromolecule: Name: Calmodulin-1 / type: protein_or_peptide / ID: 20 / Number of copies: 7 / Enantiomer: LEVO
• Source (natural): Organism: Mus musculus (house mouse)
• Molecular weight: Theoretical: 16.852545 KDa

Sequence

String:

MADQLTEEQI AEFKEAFSLF DKDGDGTITT KELGTVMRSL GQNPTEAELQ DMINEVDADG NGTIDFPEFL TMMARKMKDT DSEEEIREA FRVFDKDGNG YISAAELRHV MTNLGEKLTD EEVDEMIREA DIDGDGQVNY EEFVQMMTAK

UniProtKB: Calmodulin-1

Macromolecule #21: Cilia- and flagella-associated protein 69

• Macromolecule: Name: Cilia- and flagella-associated protein 69 / type: protein_or_peptide / ID: 21 / Number of copies: 3 / Enantiomer: LEVO
• Source (natural): Organism: Mus musculus (house mouse)
• Molecular weight: Theoretical: 106.368562 KDa

Sequence

String:

MSTAEASATT ADAAEAGGRT KTGSPRTIPV FGVAIPDGEM QGIFKPMDLN RIIKVLEEED KDVSEEKQLN YIKKLIHCYQ NGFPLRDLA QIFKILSLCA EKIEKQPCFV EPASDIIKLC GLPFLKKKVS DEITYTEDTA NSFALLGELM KIPSSALRIQ I CKCIVDFY HAEPLKKHIP GYQQVSSSYK IKMVEVGGLA KAMVQSALLL ENQLVEKLWV LKVLQHLSTS GVNCTLMVKA QA ASGICAH LNDPDPSGQL LFRSSEVLWN LLEKSSKEEI IQQLSNLECL LALKEVFKNL FVRGHSHYER QLRNDILVIT TII AQNPGA PMIECGFTRD LILFATFNEV KSQNPLVKSL KLFNCYEDFE LKKLLFNIIV ILCKDLATVQ LLIDGKVILA LFTY VKKPE RLKIMEWSAA QYEELQLHAI ATLSSVAPLL IEEYMSCHGN SRILAFLEWC GHEDSYFIHG NSFHGTGGRG NKFAQ MRYT LRLLRAMVYL EDETVNKDLC ERGVIHQLIE IFKTMMSRPA EKEEAIALEI QSDTLLILSG LCENYIQRKE MFGTEG VDI VLHVMKTDPK NLQRGLGYNV LLFSTLDSIW CCILGCYDSE DYFLEKEGIF LLLDILALNQ KKFCNLILGI MVEFCDN PK TSAHVNAWRG KKDLTAASLL IKLWRKEEKE LGVKRDRNGK IVDTKRPLFT SFQEEQKTMP LPANCPSIAV MDVAENIR A KIYAVLDKLD FENLPGLSAE DFVTLCIIHR YFDFKIGEIW NEVSEEIKLE KLRLVTTDEK SLNSIIAATE NIGKMVASL QSEMIENQAL QDVQNEQRVY AKIQATHKQR EQANKSWENF LARTSNAKTL KKAKKLQEKA IESSRYTERP QNATFHQTVI KGLNTTVPS GRVVTVQSTP TRLLGGPLAD TDIALKKLPI RGGALQRVKV KPPLNDPKKS IPT

UniProtKB: Cilia- and flagella-associated protein 69

Macromolecule #22: Sperm acrosome-associated protein 9

• Macromolecule: Name: Sperm acrosome-associated protein 9 / type: protein_or_peptide / ID: 22 / Number of copies: 58 / Enantiomer: LEVO
• Source (natural): Organism: Mus musculus (house mouse)
• Molecular weight: Theoretical: 19.512373 KDa

Sequence

String:

MNEVKESLRS IEQKYKLFQQ QQFTFIAALE HCRENAHDKI RPISSIEQVQ SYMEHYCNNS THRRILIMFM DICSELSKLC QHFEALHSG TPVTNSLLEK CKTLVSQSND LSSLRAKYPH EVVNHLSCDE ARNHYGGVVS LIPIVLDFMK EWIAHSEKLP R KVLQHGTT

UniProtKB: Sperm acrosome-associated protein 9

Macromolecule #23: Protein dpy-30 homolog

• Macromolecule: Name: Protein dpy-30 homolog / type: protein_or_peptide / ID: 23 / Number of copies: 6 / Enantiomer: LEVO
• Source (natural): Organism: Mus musculus (house mouse)
• Molecular weight: Theoretical: 11.224607 KDa

Sequence

String:

MESEQMLEGQ TQVAENPHSE YGLTDSVERI VENEKINAEK SSKQKVDLQS LPTRAYLDQT VVPILLQGLA VLAKERPPNP IEFLASYLL KNKAQFEDRN

UniProtKB: Protein dpy-30 homolog

Macromolecule #24: Unknown1

• Macromolecule: Name: Unknown1 / type: protein_or_peptide / ID: 24 / Number of copies: 1 / Enantiomer: LEVO
• Source (natural): Organism: Mus musculus (house mouse)
• Molecular weight: Theoretical: 4.868993 KDa

Sequence

String:

(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK)(UNK)(UNK) (UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK)(UNK)(UNK) (UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)

Macromolecule #25: Spermatogenesis-associated protein 17

• Macromolecule: Name: Spermatogenesis-associated protein 17 / type: protein_or_peptide / ID: 25 / Number of copies: 2 / Enantiomer: LEVO
• Source (natural): Organism: Mus musculus (house mouse)
• Molecular weight: Theoretical: 45.57916 KDa

Sequence

String:

METNSNNFGE LQELKDMATL AKLLARAPFL ESQYYFRNRA VDSFRKFEND AAVMIQSWFR GCQVRAYMRH LNRVVTIIQK WWRSYLGRK FYQLVVEAAY YTMKMNLYNE MAVRIQRRWR GFRIRKYCFN YYYLKEYLRA VSETNDAIRE ALEEFAEMKE R EERKVLLE REEKQKDYQA RKMHYLLSTK QISGIYNSPF REHPDPWELR LQKAKPLGHQ KYTAEKGKTS QSPSNWLACT SV HSFPQSE SLPPISRKRC QGPFRDINEV LEQRYKPLEP TLRVAEPINH LRLAREAFKQ EERMRNVQDK MFLPFSSYHK KEK YIPMIH SSSAYNSDSY GQKHFRSQDS KKWISDKDFQ TVLPSFQLFS KYGKLYSKAG EIV

UniProtKB: Spermatogenesis-associated protein 17

Macromolecule #26: Cilia- and flagella-associated protein 119

• Macromolecule: Name: Cilia- and flagella-associated protein 119 / type: protein_or_peptide / ID: 26 / Number of copies: 6 / Enantiomer: LEVO
• Source (natural): Organism: Mus musculus (house mouse)
• Molecular weight: Theoretical: 37.912082 KDa

Sequence

String:

MITPSSSQSL GMKVQMESEQ SPKLQEELDR SPSSVDGSAI RNGTDMQTES PAEATSSPVE VAEDPGANLF PPPLPQPRIC MWKYLDIHS MHRLEKAATV EKMREVLAEL LELGFPEQSL RDAIILDLFS HALIFCRQQG FSPEQTSAAC AMLQDLHKAC V ATPLGNVE ECYRYFTSVL FCHGIRRPPF SIDLFKEEQL LALADYVVNT YFRHFKLYKY VFTPQVRLDL SLTYTGLQPL TL WPEEKEN EEMMVVEQVA TPQEEEPETV TEPEQQPSEV CILQTYIKSQ LSKELRQLQQ LVEERLKESE ERLSSKLAAL EQP FQTPPS KGKTKTK

UniProtKB: Cilia- and flagella-associated protein 119

Macromolecule #27: MORN repeat containing 2

• Macromolecule: Name: MORN repeat containing 2 / type: protein_or_peptide / ID: 27 / Number of copies: 3 / Enantiomer: LEVO
• Source (natural): Organism: Mus musculus (house mouse)
• Molecular weight: Theoretical: 16.815422 KDa

Sequence

String:

MASLGESQSR ESLSFTSPST SSEVYKIKFI FPNGDTYDGD CTRTTSGICE RNGTGTHTTP NGIVYTGSWK DDKMNGFGRL EHFSGAVYE GQFKDNMFHG LGTYTFPTGA KYTGNFNENR VEGEGEYTDT QGLQWCGNFH FTAAPGLKLK LYM

UniProtKB: MORN repeat containing 2

Macromolecule #28: Unknown2

• Macromolecule: Name: Unknown2 / type: protein_or_peptide / ID: 28 / Number of copies: 2 / Enantiomer: LEVO
• Source (natural): Organism: Mus musculus (house mouse)
• Molecular weight: Theoretical: 8.698714 KDa

Sequence

String:

(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK)(UNK)(UNK) (UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK)(UNK)(UNK) (UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK)(UNK) (UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK)(UNK)(UNK)(UNK) (UNK)(UNK)(UNK)(UNK)(UNK) (UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK) (UNK)(UNK)(UNK)(UNK)(UNK)(UNK)

Macromolecule #29: Unknown3

• Macromolecule: Name: Unknown3 / type: protein_or_peptide / ID: 29 / Number of copies: 3 / Enantiomer: LEVO
• Source (natural): Organism: Mus musculus (house mouse)
• Molecular weight: Theoretical: 12.188016 KDa

Sequence

String:

(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK)(UNK)(UNK) (UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK)(UNK)(UNK) (UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK)(UNK) (UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK)(UNK)(UNK)(UNK) (UNK)(UNK)(UNK)(UNK)(UNK) (UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK) (UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK) (UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK)(UNK)(UNK)(UNK)(UNK) (UNK)(UNK)(UNK)(UNK) (UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK)

Macromolecule #30: Unknown4

• Macromolecule: Name: Unknown4 / type: protein_or_peptide / ID: 30 / Number of copies: 1 / Enantiomer: LEVO
• Source (natural): Organism: Mus musculus (house mouse)
• Molecular weight: Theoretical: 4.613678 KDa

Sequence

String:

(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK)(UNK)(UNK) (UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK)(UNK)(UNK) (UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK)(UNK)(UNK)(UNK)(UNK)(UNK)

Macromolecule #31: Unknown5

• Macromolecule: Name: Unknown5 / type: protein_or_peptide / ID: 31 / Number of copies: 1 / Enantiomer: LEVO
• Source (natural): Organism: Mus musculus (house mouse)
• Molecular weight: Theoretical: 1.549902 KDa

Sequence

String:

(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK)(UNK)

Macromolecule #32: Unknown6

• Macromolecule: Name: Unknown6 / type: protein_or_peptide / ID: 32 / Number of copies: 1 / Enantiomer: LEVO
• Source (natural): Organism: Mus musculus (house mouse)
• Molecular weight: Theoretical: 4.017944 KDa

Sequence

String:

(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK)(UNK)(UNK) (UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK)(UNK)(UNK) (UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)

Macromolecule #33: Cilia and flagella-associated protein 47

• Macromolecule: Name: Cilia and flagella-associated protein 47 / type: protein_or_peptide / ID: 33 / Number of copies: 2 / Enantiomer: LEVO
• Source (natural): Organism: Mus musculus (house mouse)
• Molecular weight: Theoretical: 360.784406 KDa

Sequence

String:

MDAERGSVAP RDIDTLKKEV QLRVNPLVLK FQDAVSGKVY RLPLTVHNLG RWNQKIRFQE PSKPQFKLLL TSLDKELASG LQMTAMVEY HPNKNEDMSD HIFISVGNKV LDIPLFGLIP VCQLEIVPVV DFGTLVANSK VHCKEITIIN RGKAPGKFKA E YQGQLPIV ISPSSGIVKA KTSMVIKVDF CADQAQIVNE MARVSLQGCP ETFLNIKVRV VEQIIELFHM NSERKLECIR FG SVFFGTS KLEHALLYNN SPESINWVAI MQDDCVGEEL GTNIHQRTDI AINNISYLNK IKKIDMTDFM SCVPNEGTLL PYQ KIVITF CFSPKLVVDT KKDVGPSHRQ DYALFVRFDS VGSKDGFLRD DNSNTMKSNR LQKVELALTG SGLPVILQFD PGKS LTFAP CHMGEHSDIL CIVKNQSISL PVMYHFKKTA HFKMDPERGK IDEGCIQNVI CSFVPHQIGV FKVKQVIEII GPVAD DNLR SLSMKPFLYI HLNFSSTCKA FTRKVGVKIN PGISPLISNP TRHFVAKDSE KKDDLPPVAA MLQSTATKLH DHCLKD EST KNALIAFPND RATSIRSGDH HEHFRTIFTK IPRYDYTDPD YEYTDLEKLE RKAHRDYYTN YINNLRTIRL RKEAQRE RK FPVNEVDIGM LPLSGLKSPP LSQSEIEEEI PPSLKASSLK ANRLLSTKKI ASRESECLQR KITRGLKSKP TTHQEKQE C SKVLTPKQIH QVIVGPSVLN FGNICVKSTN THLLHIVNML PMYILIQLDV DFEELQKTKQ FSYVIPPTSS TYISMVFES STSGKFWKSF TFKINNIPGG HILVMAAILP VKLELSSNEI VLRPQSFLLK TCFRGTVRLY NHLNCPAQFG WKPVTTLRGI AFTICPAQG TVDPYCSLEC EVTWQPGFSS PDKGEFLLQV SGGNTLTLKC IAHVGHTKVT FLEPRILFSN CSQGLTTWRK A ILHNIGQN HAYFKVCDQS LLSTINIVPS EGIIPFGGIT VLNISCTPSV AEKFDTRAKV AIHHANVIDL RIGGSVEIPD VE ILPSTFN FSGTYVGTTE IIPFIIKNRG VTRARVEFNL KEFPLFAMDF KGNAGECKNV EGPYMYAIEV EEGTSAECGI TFS PVEVAT YDFSFPVLIN SFKASDLYCE YLSQQKVLMP RVSPLIPPCF VQATVLRAPL ELSSTVFLFK IPLYEFQHNK EVTR IQDLV LHNISKKTVL WSLDIGRIDK YFKSGIFKFT ALIGSLKPNE KYTISIHFCP KQTITYLADV AIRLNDNLFD YRILH LIGE IQLPKISFDP SFICFTPVPL DVTTGVDIRI LPQNYFSNST LHFKIPTAKL LDNDEIHPLT VTFPNGRVIK GSNTGL NDE ILCHLSFSSS KPVSFFANLF FSDDRNNWFS LPVTATSENC ILTIYLYLAV HLDTQRVVLK EEKQGNIKKP RGSFLVP RR DSKSFASQKM KRGSLVPKFN DAEVICGNLF VGMEISRDYF DSDESIAEKL YAKYLEKEEK CQQFFAPEEG SKAFDYFQ K VVNAAQTWFS LFGWPEGPHS LSIPETIRRD VQKIQFYSTS SPPKKFSRQS DFSKYNKTIY DVILHLSGKL PPGINAGQS LPVDNVERVM QLHLQHASLL DFITAQGGCI SHVLPEFLLE PKDYMKWLEI TTATKSTALS TLKGNYSVNI DMDNFEAWSK RAWTDVFLQ IYKVTILSRV TPHCTSSMPI LHGENKSKIS PCFASSNIYS DSERILLSWL NTNYESQRTS IWKNNKSDVP P GRWIVNFD SDLLDGLVFA TQLAAYCPFL IETYFINMYT KPKRPEQYLH NCLIIINSLR EIGFDLNIQA IDICDPNPVL ML MLCVYLY ERLPTYLPKK VVPFSCTLYD VVVGQILLKN PSLKNLVYTA TIVGRDANNF CLAQTGNVVT IGPKNHIVLV VKF VSRFLH PAEATLLLIS RPKCGIGGST LAFALKGEIR NFKAIDVIKC KAPCYQWKEV TVNVKNPFPS GGDFHVILVE STTL MYLPA QVTDSSKVSV MPDHMRSSDY AADQSSSHAE NGLRTSIKSN FIREFFCSST TLSLRPKTSS SIDVYYLPFD MHVRY CAII LSNKDIGDLI YIIEGRGLIP LPSNFLPLEP PSPIDYSTSL EEDKEDPILY LNCKPHQILD MDLKIPLTNE AKEKAL AFA AQQQMSTLEY ERRAISGTLE SSTIRAAVAL LGLTKIECLL LFNMSKLKKP KSILYTTELS LPAHFNIPRK IYIPQIP EP PDFHMQSLQI KPQIVSGERP FQKPLPSIQA ALEGTVSIPL RFAPLGSGRY PCKLLLLSRH DVRVYLLEGI VNEEVPEA E LLFKTPAFQP LTQNIPIKNE SKKLSKFHVK IEGEWFHGPP ILHVGPGETI QYPLTFKPIL ECEIMGKLTL QNEVDGMAH IVEIDGIGTK PIALDHIIID CKVGKVTDKS IIVPNYTKSL LTFKVTSDLS IVWGNSFITI EPDDSIPYTL HVCPWKRGTF KGAIMFFVK SRDEEESQEE TDTEKDFSSQ ETPSDQSTII FEEYSEEKVK ALKIWYHLEI RSSPGPPVDI IELHCIALET T CIEIPISN SKNQPVCLDV KLTCSALNGP VEMTLAPLES VTYIVWYSPA TTGYKEESII FQPEMGEEFW YLLKLTTELP KP KEIPEMQ CDLGKKIIQT LPLYNPTHET LELRIRNSNP INFVIELNRK LPLVLLPHST TELSVYFHPS GLGRHGHETC INF YCTQFK EWKFYLFGVG LYPRPIELKR VTTILGLQAS VMVHFRNPTS EDVSVDLILT NKEQPKGLAI DQCWKTFLHE NAAF RFSSL RRTHGIIVPP KGNLDIPVLF IPSTMTLYKT MVIVKMKRTN KKNWLIDNFD ELSAETKRYM GVGYGEIQAI HWMYP IIGL PQAPPPKSSP VIIRCQANKQ REEKVEVSML GSFFNTHPKP DMTEFLVFPK RNVYKSIYED VDVNSKRREF EYEIEF ESE DVKSNLDSFV TLYLFRKHFN VKSEIISLIF NVIFTPRKPF RANVTLNVEC ITEGIWKFPI TLIATEPEVE DVINIHG IG LFKTSETEFR LTSQTRYYEP FVAHFLPGSD QEFFVKPQSG ELPPFYTKGI VIIVGFKPRM YSKKYQATLV IQTDEIYW L YEINGLAPSS KSLTHVTAKV DATSKIYDCM PPIQRNFIRE NAKLRSTAVS STVKGAPLFK KHK

UniProtKB: Cilia and flagella-associated protein 47

Macromolecule #34: Hydrocephalus-inducing protein

• Macromolecule: Name: Hydrocephalus-inducing protein / type: protein_or_peptide / ID: 34 / Number of copies: 5 / Enantiomer: LEVO
• Source (natural): Organism: Mus musculus (house mouse)
• Molecular weight: Theoretical: 582.208875 KDa

Sequence

String:

MTLKIKCVAN YIKEKIPNVL FLCDPEARLQ QLTASVPLCE QRKYFKQTNK RLEESMGAMH RKMAKVISGL QSKVLPPMSP KVVTEEEVN RMLTPSEFLK EMSLTTEQKL ASTRIICRPQ ITELLDMGET THQKFSRVDL DQALFQPFPS EIIFQNYSPC E VYEVPLVL RNNDKIPRMV KVVEESSPYF KIISPKDIGH KVAPGVPSVF RILFTPEENK DYAHMLTCIT EREKFIVPVK AR GARAILD FPDELNFSTC PVKYNTQKVL LVRNIGNKDS MFHLKTRSPY SVEPTGGILN VGESMQLEVD FEPQTVGSHD GKL IVTYDT GEMVFVCLYG VAIDVNIRLD KNSLIMEKTY ISLANQRSIT IHNRTNIIAH FQWKVFATEE EEDKEKYKIC DGLN KEEKQ ETSMILEDSV LDPSLRERLS IISRTFENQR KLVQGDSMLF LDHVFTIEPP EGDVWPNSSA EITVYFNPLE AKLYQ QTVY CDISGREIRL PLRIRGEGMG PKLHFNFELL DIGKVFIGSA HCYEAILSNK GSIDALFNVI PPTSALGACF VFNPKE GII EPSGVQAVQI SFSSTILGYF EEEFLIDVNG SPEPVKMTIR GCVIGPTFHF NVPALNFGNV SYGFPHTLMC SLNNTSL VP MTFKLRVRGD GEGMSSIPSY SQESDSKQWS GINTEMPTTK PKEFTISPNS GTIRAQGFTA IKVTLCSNTV QKYELALV V DVEGIGEEVL ALLITARCVV PKLQLVTTEV DFGRCFLKYP YEKTIQLVNH DDLPGCYKVL PQLYENSPPV LLSSPSPCG VISPHSTVSI PLALETQVIG AHRSIVYISV FGSQEAPLAC NIQSIGEGPV IFIHPTQIDF GNIYVLKDTS RILQLSNQSF IPAVFRVRM ANKKSLWTVK PSEGAVPAED DIPLTLTANL DDIVTFKDTV ILEIKHSNTY RIPIQATGIG STIVSDKPFA P ELNLGAHF SLDTHYYRFK LTNKGRRVQQ LFWMNDDFRP KEKQSKKEPG KKGSTSSSRR QSKASQEPTD NGNPVFQLYP VR MELYPGQ TIDVILEGYS ATPKKVKEKL VCQAIVGTQK GKSLLMSVNI ICEFIAPIIQ LSAKQLLYRL EKKPNSNLES DYQ SLVIKN ITTLPVNMLL STTRPFFICE TDKSLLPATP KPIKLEVDEE KHLLIKFDPS YRNDLNNWVA EEVLSIKYLE HPQV DNLGL RAEVHYPNLS FEVMDIDFGC ILNDTEVIRY IMITNCSPLV VKFRWFFLVD EEENQIRFAP CMKPYSAFLS QMESI AATS VTASSLAAPH TVEYTEMDFS DSIKTILMDD EAGPEEIKKP ATSTMVSEAI KYSSAGTERS QSQPDYPECM WIYEQD EML SIGIEEVFDI LPLYGVLRPY SSHQISFTFY GHCDIIARAK ALCEVEGGPT YEVLLKGEAS LVNYSFDTKD INYGLQL FD HVTEREITLK NTGKVGFEFN VLSNYRSSQR NLLPGVPLIL PLSGFIQSNK EQVLKVYYLP GIPEVFQRNF QIQIAHLV P ENITLYGEGI FPRISLDLHR NLQGNEKYEH FLEQAKKNVE KEYTKYEAVD QYEVMAEELP EEETAEISAH VQMEVERLI VQDYALEHQR SISNNTEDIY FSQRSCRKLT KVQLPEYILD FGYIVLGDVR THIVKITNTS HFPVSFHAEK QVLHETGFST ELDRVKNLP YYETETFEVR CDPQGANLPV GNKEVILPIK VYGGPTIHLC LQATVIIPSM TLSCNKIEFA TIQCGQCMVE T IQLSNHLQ VPCEWFVHTP KSTNKLDKHM PKYLRRKLQA EMIPKSRIFE IQPTSGILDP GERANVQVKF MPKEEKLYSQ SL LFQIGQS SQKLTLLAQG QGLEPRLEFS PSVLELGPLL PFASGDEAEV IVRNPCNFPI EFYSLEFDQQ YLLEEKMLRQ LKG YDSYNT LLLPPRNPGE KLPPEVYDYF KEMKKSKEEH MKAKYMENLE NEEEEMNTSD QGTTSTKRTS ISRGISVTSN LEER HLTIE AKNYLDEDDY EESLEKLTFQ TDKMQSTDSH SVEEVGEVES NPVSKAIARH LGIDISAEGR LAKNRKGIAI IVHGT PLSG KTANAISMAK FYNAACLNID SIVLEALSDT NNILGIRARE LCIRAAIEQS MREAEESAHE SSMTQNTVVP ARLSTE NLG RFTSELTLIT QEYKVPKTVR GSVMLPKGKA DSHFTGSQKQ HHQHQSETPQ VQISSSPLLP GPTHRRLSVS ASIGGET GL MSCVLPDDLL IQILAERIQL SNCFRGVVFD GLDTLFARNA PSALHCLLKA IGSREHIYVI NMSQDYVVMK AQEKAKKE Q EENKRKEALA KEKERLQTLD EDEYDALTAE EKVAFDRDVR QALRERKKRE LERLAKEMQE KKLQQELERQ KEEDELKRK VKRPKAGPAA KEEPPLKKAQ GATNKQLAAV AKIELKMESI ERKVSVREHA TLEETTRKKK AMTEYPLLIP ISQEQEDSEG DFLKDSDKN LAQKFKIYDM CLKDVQNILM YWDRKQGMMV PHTGTDEMSH EADDQRQAPS GGGGRKGRKD RERERLEKER A EKERLERE KAERERLEKL KALEERSDVE GEGEEEHEGK KDLGVPFINI QSPDFEGVSW KQALESDKLP KGDQILDILG LG SSGPPIP PPVLFSIISY PAKRQSLVAT EILKHFVFVI PPNDDIPLMD EKKDPEGDSD IFLNTIITKA QEEQPSPPKG SKQ KLKDKP EQVRETQKEK RRTYSSRKGL PGGTSGSIVP MSDIDQNSFD GEHSQEKFIR LNHFRWIVPP NGEVTLRVHF SSLD VGNYD QTFNFELLGT RRQYQLYCRG VCTYPYICRD PKVVFSQRKK DMKLKEVVVK KYVVSMEKFY FGPLLCGKSR DKYKS SLFP GNMETLTILN DSPMVVEAYF CFQHDIKAST YFLEPVNMTL KPNEKQALNV WAYPTAVGIF EDSIVCCIKE NPEPAI FKL SCQGIRPEIE VEPRQLHFDR LLLHRKETKI VILRNVTPLP VAWRISNLEH LGEDFTVSMM QGTMLPKGEY GLQVHFQ PS KPVNIKKAIR IEVLDAENLV GVVQIENILI FAESYDIALD ITFPKGAEGG LDFGTLRVME EVKQTLQLKN RGKYEIIF S FTVDTLGVLP TNLSSMISVQ PKRGTLASID KPTTVQVFFR ARKEVKIDCQ PILRCQIIEP TLPEGEIIAS IPIKFSVNA VYSKFTISPS SIINFGALIC GTRKSITFTI ENQGIIDFKY ALYRLTGESP ILQKKITSHM RHGRTRESES FYKPGATKMA KFSDTVQKD TNIANQARFT HGMFTVYPGF GSIPSGGQQV ITIECFADPV GRCEEFLAID ISDRDPRENP AGIPYTLLAE A CLPAFVTD NNILIFEEHQ ICTSPNLYHI LQTIQSGGLF VEDENKFIFC NVLVGHQAKA RFKISNVGKI SCDINIVIKP IS NKPANRI TDTFDVEPSK MCIGSRSHAF VTVLFTPQTM QTYQCIFEAT LDGLPSNIAR SRGLVFDIVG EGTLPRVTVI RPT LYNQHG NPLLLFKRLL LGHSEKLPLI LKNNGTIPAQ LHVDLRDQLG VFSLKGRPTT SYIYIMEENK PNEKVKKAHT ASLV VSPGD TAEFDVFFHS NKIGRMTGTI HLSVINNQYE ETMIHLVGES YEDDITLDNI HGLISSTSQE SSDKSEVIEI AEEST MEDL VTAALMEHIQ FGYCHIGISY NVSFTITNHS QVNVIRFEWP LLATLSFSPQ IGHLHPGCSK DVVVTLKSES PITLKK MCV KCKLSKIMFQ LPVDQVPDWD DRMRTVKWVD APRNTPLTLN TKRKVIEMDP EPAHSVVEEN YRELRIQFSA NVDFASY QC ETTEVFFKET LVYQTRVFEF DLVNTGQVLL EFCWISEEAS KAVSFAMPER QGSSQKELSQ GSGSSLDSAL DRWTEASP S PFSVEPPSGV VPVGKTQKLK VKFSPMDIGE FESSLYCQIP NLPLGEQGPI LITKGRSVLP FCHFDLKESD YISGHRRNP ELRGPGAGPL EPNTRVIEFT SVGIGGKNVQ TFTILNPTNS TYSFCWTSEE TESLQHPPAF VCLTEKGIIH PEKKAEIIFQ FLPAHLDIT EEFWTFSIPE HNISVPFLLV GKTTDPLISL DKSHLNFSSL LIGREARETV KIINKEEQGF NFAFQDNSRY S EGFNNSLI VCPMEGWIPP LSRFPVDIFF TPKQEGDVNF NLICNIKKKA HPLTLNVKAE GYTMNAEVKC RDRMGTTILL TS TQVNTIN FYEVELNECV QCEFSFINTG KFNFSYQAEL SGPKLLLQYL DFTPTDSSVD VGQSEPANLS FQPYQKCVLK GLE LKIKIS HGPTFVCNIL GCAVSPAVHF SFTSHNFGTC FIYQAGMPPY KQILVVTNKE ETSMSLDCLY TNTPHIEVNF NVDV IKPGK TLEIPITFYP REAISYRELI PFEINGLSQQ TVEIKGKGTE MKLLVLDPAN RIVKLGAVLP GQVVRKTVSL VNNSL AQLT FNHSVLFSIP ELQEAKVITL EPFHTITMKP KEVCKLEITF APKKRVPPFS EEVFMEWMGL LRPLFLLSGC CQALEI SLD QEHLPFGPVV YQTQATRRIL IMNTGDVGAR FKWDVKKLKP HFSISPEEGY IISGTEVALE VTYHPTEIGK ESLYKNI LC FIQGGNPLCL TLSGTCVGPP VVKEVVNFNC QVRSRHTQTI LLSNRSNQTW NLHPIFEGEH WEGPEFITLE AHQQNKPY E ITYKPRTMNL ENRKHQGTLF FPLPDGTGWL YALHGTAELP KAVANIYREV PCKTPYTELL PISNWLNKPQ RFRVIVEIL KPEKTDLSVT LKGLDYIDVL SGSKKDYKLN FFSYKEGLYT AKVIFRNEVT NEFLYYTVSF RVTPSGIIKT IQMTSPVRQS VSASIKLEN PLPYSVTFST ECKLSDISLP SQFAVPPNSE GTFSFEFQPL KAGELCGRLT LHNSDLGYYQ YELALKALPA P PEKPVHFQ TVLGSSQSIL AKFTNYTRLK TEYYCKTDCS DFHTEKVINA APGAQGGTEV SVEVFFEPSH LGETKGILCL SS LIGGEYI IPLFGIALPP KPQGPFLIRA GYNIIIPFKN VFLHATSFSF IVENPAFSIR AAETVRPKKI NNITVYFEGN PSG SKTPIT SKLIVTCPQC EGTESGIKWV YYLKGITP

UniProtKB: Hydrocephalus-inducing protein

Macromolecule #35: Germ cell-less protein-like 1

• Macromolecule: Name: Germ cell-less protein-like 1 / type: protein_or_peptide / ID: 35 / Number of copies: 4 / Enantiomer: LEVO
• Source (natural): Organism: Mus musculus (house mouse)
• Molecular weight: Theoretical: 59.72298 KDa

Sequence

String:

MGALSSRVLR PAGRTEQPEP TPGAGGAARR SDAGEDAGHS FCYCPGGRKR KRSSGTFCYC HPDSETDDDE DEGDEQQRLL NTPRRKKLK STSKYIYQTL FLNGENSDIK ICALGEEWSL HKIYLCQSGY FSSMFSGSWK ESSMNIIELE IPDQNIDIEA L QVAFGSLY RDDVLIKPSR VVAILAAACM LQLDGLIQQC GETMKETISV RTVCGYYTSA GTYGLDSVKK KCLEWLLNNL MT HQSVELF KELSINVMKQ LIGSSNLFVM QVEMDVYTAL KKWMFLQLVP SWNGSLKQLL TETDVWFSKW KKDFEGTTFL ETE QGKPFA PVFRHLRLQY IISDLASARI IEQDSLVPSE WLAAVYKQQW LAMLRAEQDS EVGPQEINKE ELEGNSMRCG RKLA KDGEY CWRWTGFNFG FDLLVTYTNR YIIFKRNTLN QPCSGSVSLQ PRRSIAFRLR LASFDSSGKL ICSRATGYQI LTLEK DQEQ VVMNLDSRLL IFPLYICCNF LYISPEKRTE SNRHPENPGH

UniProtKB: Germ cell-less protein-like 1

Macromolecule #36: Sperm flagellar protein 2

• Macromolecule: Name: Sperm flagellar protein 2 / type: protein_or_peptide / ID: 36 / Number of copies: 3 / Enantiomer: LEVO
• Source (natural): Organism: Mus musculus (house mouse)
• Molecular weight: Theoretical: 198.248422 KDa

Sequence

String:

MSEILCQWLN QELRVSRTVS PKSFAKAFSN GYLIGEVLFK FELQSDFAEF SESRGSTAKL NNFSRLQPTL HLLGLQFDQN VAQSIITEK PGAATKLLYQ LYIALQKKKK TGLTGLEIQT MQPQTNLRLQ TLKSEAFREQ RLNRRRQNEI MAKIQAAIIQ I PKPESNRT LKAIEAQKLM KKKKEAEDVA NEIKKFEALI KKDLQIKESV SKTSLETTDQ TTAELLNTYS DDDYIKKIQK RL EEDAFAR EQREKRRRRL LMDQLMAHEA QEEAYREEQL IHRLMRQSQQ ERRIAVQLMH VRHEKEVLWQ NRIFREKQFE ERR LKDFQD ALDREAALAK QAKIDFAEQT LREKEIHEKI SVERAQQRYK KHYGICAEIL DQMLDLCTKV ADYRLLTNNL IPHK MMHDW KELFFSGIPI YEQTSLTHGQ TEPTEDHRAE VKKRNLLDSK DYEDYKNMVG EWALPEDMVN SSPPSNNSIL GHVLL RLIE KADPSASNAE ATELPSLAVK GCILGKTLSG KTTVLKSLQN DFPVHVLSID TLVQEAIQAF HERQKSGKTP PTQEDD KRD PVVNQEKVSK TQDKNVLAVS PVPGDRTSQK EGVKINEFEQ FRSSDSFLSL SMRAQLGAKS ELMLRRGKSI PDILLVS IL VNAIKEIPVD QSWVLDGFPI TLNQAKLLEE ALTGYKRKFL QLKKKKEQMP TLALDPSTST EVSLLPSALD FVILLDIS D NSSLARTNDI IAKEISHEIS HENVGRPGTG TSQDNKSEDR NLRDHIQHRI VGFLDNWPLL EEWFTQPKNI LTKVNAEID EALLCQKVKE IFATETVNKK IKVEKTLEEK ETEKKAGAPP AEPPAMSPPL SSEAEKDKEL HQAKTPGKGK TQSVSPKGKA QGGKVSVKK SPVGSAEVSP TPTAPPPPKA GTEEWVYVNE PIPEELPSFL VPYWELIEKS YINHIKTVLR HLRERQHNVL S YLYETRTS FQEFLRRPDH KQDFVSQWQA DFNSVPEDLW EDEETKAELH QRVNDLRDRL WDICEARKEE AEQERLDIIN ES WLQDSIG ITMNHFFSLM QAEVNRFQDT KRLLQDYYRA MESKIPLEDS KKFTRVPLVQ LDGKEISESQ LRIPLVPRIS NSP ENSAVK PKVGTFLKGR SDPPLEVLEA NFEIDEKILL DTWQQASLAI SNMVAAEVHQ RLTEEEKEPP QLDSKEKSPQ SGAN KKAKK EKEAPKKKKT DKKGKGKSSP VAEVSPVTVT PEEMAEMEKR NELRLRIKEE HLAALQTEEQ AAQFRLELIK LKALS VLED LVTKVIDVYR LMEKWLGKRY LNEMASIQKL TELARYHIET ATKIQNEIYL SQEDFYINGD IKVFPDPSPP TRPPPV ERE ENGTLTIEQL DNLRDQFLDM APKGIIGNKA FSDILLDLIT LNLGTNNFPS SWMHLSQLDL QEITSLLTVN TEFVDWR KF LMVTAMPWPM ALEDELLDTL QRFKALDEAQ TGTITYEQYK QAGLWFSGDE DIKIPENPLE PLPFNRQEHL IEFFFRLF A DCEKEPPQLD YTQMLLYFAC HPDTLEGVYR ALSVAVGTHI FRQVETPMLM AEKTSISTVS PIEEFPETEE SSAKEDREL KEEKDDQKEE EIPENANTEK ISMETLLKVF GGGNEVLDAN RFASYLKSEN IYAENFIKTF QDLGARNLEP IAVNILLKHP YIQDLIANY VDYKFPDIKM ILQRSEHAQG SDGERSPSRL TDEKK

UniProtKB: Sperm flagellar protein 2

Macromolecule #37: Leucine-rich repeat and guanylate kinase domain-containing protein

• Macromolecule: Name: Leucine-rich repeat and guanylate kinase domain-containing protein; type: protein_or_peptide / ID: 37 / Number of copies: 3 / Enantiomer: LEVO
• Source (natural): Organism: Mus musculus (house mouse)
• Molecular weight: Theoretical: 93.30468 KDa

Sequence

String:

MAAFERNPSR WKGTRFRRGL GASRIAAQAI LSLTEKQSQG RWPSFPLGLK SKGTFRSASS YLLHQLIHRS HEAEAEQEEK QQEDGESEE SEESEMQNLE DKYDGILREE TVAEAITGLG WSGRGTEQVY LNLNLSHCEL VDISILCGYV HLQKLNLSGN R IEDLSCVS CMPYLLELNA SQNKLTTFFN FKPPQNLKKV DFSSNLISEM YDLSAYHTLT QLILDNNEIE EITGLENCIS LT HLSLAGN KITTIKGLGT LPIKVLSLSN NMIETITGLE ELKALQNLDL SHNQISSLQG LENHDLLEVI NLEDNKIKEL SEI EYIENL PILRVLNLLR NPIQTKPEYW FFVIYMLLRL TELDQQKIKV EEKVFAVNKY DPPPEVVAVQ DHMTHVVNSM SQPQ RIWDS TLPSLDAPYP MLILTGPAAC GKRELAHRLC RQFSTYFRYG ACHTTRPPYF GEGDRVDYHF ISQEVFDEML NMGKF ILTF NYGNHNYGLN RDTIEGIARD GLASCIHMEL EGVRSLKYSY FEPRYILVVP MDKEKYEGYL RRKGLFSRAE IEIAVS RVD LYVKVNQKYP GYFDAVINAD DMDIAYQKLS ELIREYLGLT ETAAKTLAPT ADTKTSYLKC EDYSRKSSTV EFLDSTD RN YFTKLWAKLS SKKSPVERES LHRQHEAARQ ALMGKTPRDH TLLFQRGPVP IPTVSGQQYF ATIDELQKTF ELSDDLFK T PSGTYPETSK DSNISKRYST YFHTCPWSKE LPFQLPEGGI SSRPGSAGSD EVDGALKALR VASSMQEKVA QHKRLSAIT IMDPGSNTKP TLPPIPHGRR

UniProtKB: Leucine-rich repeat and guanylate kinase domain-containing protein

Macromolecule #38: Putative aspartate aminotransferase, cytoplasmic 2

• Macromolecule: Name: Putative aspartate aminotransferase, cytoplasmic 2 / type: protein_or_peptide / ID: 38 / Number of copies: 6 / Enantiomer: LEVO / EC number: aspartate transaminase
• Source (natural): Organism: Mus musculus (house mouse)
• Molecular weight: Theoretical: 45.505746 KDa

Sequence

String:

MTSLSVFRDV PTAQKLEGSL LKIYRQDGYP SKLFLAYKVC MTEEGHPWVS LVVHKTRLQI AEDPSLDYEY LPLVGLKSFI QSSLELLFG KHSEAIAEKR VGGVHIVGES GAFQLGAQFL KTWRKNVKIV CIVSCQKEQC GLIFQDMGFI VYEYSIWNAS D LCSDPSMF VEVLQHIPVG SILVIGNITD CKFTQNQWTK LMSIIKSKQI FPFFDIPCQG LSTGDLEEDT KILQYFVSLG LE FFCSQSL SKNFGIYDEG VGILVVAALS NQHLLCVLSQ LMDYVQALWG NPPATGARII TSILCNPALF GEWKQSLKGV VEN MMLIKE KVKEKLRLLG TPGSWDHITR QSGTHGYLGL TYQQVEFLVK KKHIYLPKTS RINFTCINAR NIDYITQSIH EAVM LTEG

UniProtKB: Putative aspartate aminotransferase, cytoplasmic 2

Macromolecule #39: Leucine-rich repeat and death domain-containing protein 1

• Macromolecule: Name: Leucine-rich repeat and death domain-containing protein 1; type: protein_or_peptide / ID: 39 / Number of copies: 2 / Enantiomer: LEVO
• Source (natural): Organism: Mus musculus (house mouse)
• Molecular weight: Theoretical: 97.243797 KDa

Sequence

String:

MSEDGSNVEP GGFPRFESLE EPGSEISDLL DEASPYSKSK DSNQIYEANP SKDTEQSAAS FTSQLDRNEE KNTGIPFSET NIADIIPLS IEESLQSSGS SETKMAEDYY PVKFPTGRKF RGRIFNGNQK GLDMKSDNFT VNLDAKGLQE FPVDIVKVKY V KYLYLDKN QIKNFQGIDP GDLLGLEILS LQENGLSSIP LEIQLFHNLK ILNASYNEIS QIPKELLQLE NMRQLLLNSN HI DTLPSGL EHLRYLETLS LGKNMLTYIP DSLSSLKNLR ILNLEYNQLT IFSKSLCFLP KLNSLNLTGN MIGSLPKEVR ELK NLESLL MDHNKLTFLA VEIFQLPKIK ELHLADNKLE AISPKIENFK ELRLLNLDKN LLQSIPKKIS HCVNLESLSL SDNN IEELP KKIRKLKNLR QLHVNRNKMI TMTEEISHLS NIHILEFSGN QITHVPIEIK NCRKITRVEL NYNNIMYFPV GLCAL QSLD YLSFNGNYIS EIPVDMSFSK QLLHLELNRN KLTVFSKHLC SLTNLEYLDL AKNQIMTIPS CISAMVSLHV LILSDN KFE SFPKELCSLK NLRVLDISEN KLQKIPLEIS KLKRIQKLNL SNNIFTNFPV ELCQLQTLEE LNISQTSGKK LTRLPEE VS HMTQLKILNI SNNAIKDIPK NIGELRSLVS FYASNNQISS LPSSFLSLEV LQSLDLRGNN MTALPSGIYK LSSLKEIN F DDNPLMRPPM EICKGKEMHM ITCYLQRADE RDEKILEKIF NIVANSITET NFEFLQQKLN MASSANNMPV RPTTPLNER IYQALIKWKA EKDVQFTATA LRDKLFRALN MIGAYDIMDK ITALNLYTSA IKL

UniProtKB: Leucine-rich repeat and death domain-containing protein 1

Macromolecule #40: G protein-coupled receptor kinase 3

• Macromolecule: Name: G protein-coupled receptor kinase 3 / type: protein_or_peptide / ID: 40 / Number of copies: 1 / Enantiomer: LEVO / EC number: beta-adrenergic-receptor kinase
• Source (natural): Organism: Mus musculus (house mouse)
• Molecular weight: Theoretical: 79.774852 KDa

Sequence

String:

MADLEAVLAD VSYLMAMEKS KTAPAARASK KVVLPEPSIR SVMQRYLAER NEITFDKIFN QKIGFLLFKD FCLNEIGEAV PQVKFYEEI KEYEKLDNEE DRLRRSRQMY DAYIMRELLS STHQFSKQAV EHVQSHLSKK QVTATLFQPY IEEICESLRG D IFQKFMES DKFTRFCQWK NVELNIHLSM NDFSVHRIIG RGGFGEVYGC RKADTGKMYA MKCLDKKRVK MKQGETLALN ER IMLSLVS TGDCPFIVCM TYAFHTPDKL CFILDLMNGG DMHYHLSQHG VFSEKEMRFY ASEIILGLEH MHTCFVVYRD LKP ANILLD EYGHVRISDL GLACDFSKKK PHASVGTHGY MAPEVLQKGT CYDSSADWFS LGCMLFKLLR GHSPFRQHKT KDKH EIDRM TLTVNVQLPD AFSPELRSLL EGLLQRDVSQ RLGCGGGGAR ELKEHIFFKG IDWQHVYLRK YPPPLIPPRG EVNAA DAFD IGSFDEEDTK GIKLLDCDQD LYKNFPLVIS ERWQQEVVET IYDAVNADTD KIEARRKAKN KQLGQEEDYA MGKDCI MHG YMLKLGNPFL TQWQRRYFYL FPNRLEWRGE GESRQSLLTM EQIMSVEETQ IKDRKCILLR IKGGKQFVLQ CESDPEF AQ WLKELTCTFN EAQRLLRRAP KFLNKPRAAI LEFSKPPLCH RNSSGL

UniProtKB: G protein-coupled receptor kinase 3

Macromolecule #41: Serine/threonine-protein phosphatase PP1-gamma catalytic subunit

• Macromolecule: Name: Serine/threonine-protein phosphatase PP1-gamma catalytic subunit; type: protein_or_peptide / ID: 41 / Number of copies: 1 / Enantiomer: LEVO / EC number: protein-serine/threonine phosphatase
• Source (natural): Organism: Mus musculus (house mouse)
• Molecular weight: Theoretical: 37.030777 KDa

Sequence

String:

MADIDKLNID SIIQRLLEVR GSKPGKNVQL QENEIRGLCL KSREIFLSQP ILLELEAPLK ICGDIHGQYY DLLRLFEYGG FPPESNYLF LGDYVDRGKQ SLETICLLLA YKIKYPENFF LLRGNHECAS INRIYGFYDE CKRRYNIKLW KTFTDCFNCL P IAAIVDEK IFCCHGGLSP DLQSMEQIRR IMRPTDVPDQ GLLCDLLWSD PDKDVLGWGE NDRGVSFTFG AEVVAKFLHK HD LDLICRA HQVVEDGYEF FAKRQLVTLF SAPNYCGEFD NAGAMMSVDE TLMCSFQILK PAEKKKPNAT RPVTPPRGMI TKQ AKK

UniProtKB: Serine/threonine-protein phosphatase PP1-gamma catalytic subunit

Macromolecule #42: Microtubule-associated protein 1S

• Macromolecule: Name: Microtubule-associated protein 1S / type: protein_or_peptide / ID: 42 / Number of copies: 2 / Enantiomer: LEVO
• Source (natural): Organism: Mus musculus (house mouse)
• Molecular weight: Theoretical: 103.058219 KDa

Sequence

String:

MAAVMAAPEA VEAPSSLLLL VVGGECGCPG LLAYVMEELE RGVRSWEDVD PAVCSLDEQL KAFVSRHSAT FSSIVKGQRS LHHRGETLE TLVLLNPSDK SLCDELRNLL MDPAPHKLLV LAGPCLEETG ELLLQTGGFS AHHFLQVLGD KEVQDALASA P AAPALTVS CPTFGDWALL GPVPGLQLRL NPPAQLPASE GLRAFLEYVA ESLEPPSPFE LLEPPAAGGF LRLARPCCYV FP GGLGDAA FFAVNGFTVL VNGGSNPKSS FWKLVRHLDR VDAVLVTHAG ADSLPGLNSL LRRKLAEREA AAGPQGQHEE RLR RLLSPA LGVVFLNARE AASRLRGGED EAVCARSLLR SLGIAPLPLQ RGPQPSCPTV LFEKLGVGRL ELFVLHPPPG DPAA PACAL LVWQPAAPGD KVVRVLFPGR TPPARLLDGL QRLQHLPCLR RPVVTTHDLE APSRANSQDS LASRDSARKE PVRGT VGSI ANRSTVRREP ALATRDQKKD TRSGPTQPTA RDTRRSGPGV VNTKPRVSQN GPRAPVLAAP LTAPVAECPG EAENIL ESE RPPAPSPTLS PAQSPPPTAP GNSPERLSLS PLRPEPAPDA SPSATTPTLT TPSLPAELGS PHSTEVDESL SVSFEQV LP AGDPGLSLPL RLARRSTSPH DVDLCLVSPC EFSHRKPPPP ASPGSSDSSA RSQERPPETP PTSVSESLPT LSDSDPVP V ADSDDDAGSE SAARDPPPTP RVPPPLPDVP GICMVDPEAL PPRARQPLNT TNPSRSRKAP ARPSSASATP RAATVAAKT KGPAGDRNRP LSARSEPADR PGRVPLTRKP SVPKTVPKMA SATRLSSGPS GRPAPLAAGS PVYLDLAYLP GGGAGHLDQN FFLRVRALC YVISGQGQRQ EEGLRAVLDA LLAGKRQWDL DLQVTLIPTF DSAVMHRWYE ETHAQHQALG IRVLGSGSLV S MQDEAFPA CKVEF

UniProtKB: Microtubule-associated protein 1S

Macromolecule #43: Cilia and flagella associated protein 99

• Macromolecule: Name: Cilia and flagella associated protein 99 / type: protein_or_peptide / ID: 43 / Number of copies: 3 / Enantiomer: LEVO
• Source (natural): Organism: Mus musculus (house mouse)
• Molecular weight: Theoretical: 76.053766 KDa

Sequence

String:

MTYYEKCIEI VIKQLDKFKP GKDNPEQFVE TVFTSLQQTL SPQKFGFVLE VLSGCLEYHK LLTIVVDAFY ARDGHTCLWS DYSLFEVIC YLAIFQLEEL GFQLFCSIIK SQPVRKMCKF LRFFFNPLNL SSWIKDEWSL IYETAHVMEN WIDPLLRWQP E VQKLIKQL EGVPTDQIPV LKTKAKVTVP KEFNLTVPRP RAITMPEPVP TMDKPRPVPQ STYKEPKEQK LLQIIKTCNR RT AEELLLK ANMEELQCAM PRVQREPQEQ DVEKQLWHQS VPHIRRTPNL TFYKPNNLPV KLNTATILRE GALYQRQVEK ELQ RVDKLV DGAGDFSEFL KWQKKMQAQD LEEQLAAGEC RRLQGKLSHE EAILARQNLM QENKQKADRQ KEETAELMLQ CAER RLQEE KAMKELVEQV TEAQKNVKIV QTKLVKGRQQ IVQEVIEESR ELLQRSAKEA KEEQKRRCEL IAHLRAMETQ PTRKG KLVD LTQIPGYGLE GEMSVVELRE RLAMLKETQK REQEEKRDQI IQDKRAKSQM IQNTVEQISL CRAAMGRTAA LRWEEK KAQ ATSPGTPSQD ERVLELKRKM EERAAERRRQ TAPQLTSPPR ALRPNQRAQE EMQHWLELDQ SRERRLRARQ EANRTCH AT HHLEAS

UniProtKB: Cilia and flagella associated protein 99

Macromolecule #44: Ankyrin repeat and MYND domain-containing protein 1

• Macromolecule: Name: Ankyrin repeat and MYND domain-containing protein 1 / type: protein_or_peptide / ID: 44 / Number of copies: 1 / Enantiomer: LEVO
• Source (natural): Organism: Mus musculus (house mouse)
• Molecular weight: Theoretical: 102.124492 KDa

Sequence

String:

MKLGYGEFSW PTGEAYHGQF YRDHFHGLGT YTWPDGSSFT GTFYLSQREG YGTMHTKTML FQGLYKEDQR FGPGIETYPD GSQDVGLWF REYLLKLCTR VPSGFSLVNY PEFLAFLTKS RRRLDLSDEK VELGLSEEQD PFFYDYKQYL LNDELKLPPE M HVYSTDNS HLPMTDSLRQ ELDDHIFMNE IPPFIEDEEP WLITNETPLL VKIQKQTYKF RNKDAHTSWN IPAILEGNRS RF GPSGPKE QISKKMIMKA EEGDYNWIFG ILRDNLACAD VADSKGYTVL AAAAMHSHLD IVNLLLDFGA DVNKRSDEGI TPL SMCFLQ YYPCKSFHPN IAERTLLQES PKSLVTPKIS FLLADANIDY LYDVGMPIAG GDELKTSSLD DSLASMQTPE SSNM LHKEE VSPVKTVSTD VEKESEGAAE NVDASTLYSV DTNFESTKCL RNYTINVSRD IMEKSAQAYS SLPQHPCFPY KGTVR KMAQ SMVERRNRWM TITLLLRRGA DPNLCQVPMQ ALFLAVKAGD VEGVRLLLMS GAQTDIQFPP QLQSLTPLHI AVSLPG EEG VKITELLLHV ITNVDAKAAD EDYVYKGGKA DLLPSSLKLN NEPGPPKSFY STHTFIPEEG GRTALHVACE REDNKKC AR DIVRLLLSHR ANPNVLWSGH SPLSLAIASG NDLVVKELLS QGADPNLPLT KGLGTALCVV CDLVYEQQRS VENKIALI D RLISYGADVL NPVTLVQGDR TAVGTAVDYG YFKFFQDRKI AHCPFHALMP AEREVFMARK RLLEYLGLQL RLAVLSKES RLDTKALYLS KRAELAPCHR LKKKGSSSVR TQSSEKQSIP FYKFCYQCGR SIGVRLSPCP RCYGILTCSK YCKTKAWIEF HKKDCNDIM AMIPHLEGSA WRVAESP

UniProtKB: Ankyrin repeat and MYND domain-containing protein 1

Macromolecule #45: Leucine-rich repeat-containing protein 43

• Macromolecule: Name: Leucine-rich repeat-containing protein 43 / type: protein_or_peptide / ID: 45 / Number of copies: 1 / Enantiomer: LEVO
• Source (natural): Organism: Mus musculus (house mouse)
• Molecular weight: Theoretical: 75.038453 KDa

Sequence

String:

METSESSTSD YRQTEGEGEG VPGTLSTAVC EHLRKLCLRE FPCGIGSWNK SRFLPQKCRV WRELVPKEEE TLVPEEETVE ALLGLVRSN HSPWAMLKDA SAEDRFLREL AIQNPLMIKD TFFYSYFRSL RVVNKGVSLV DKDLLKFLKL EELVLSANKI E EIDANNLP PTLKVLELYG NLIASMECLC SAPPPRLQHL GLGHNKLLGP LESLYVTSHN WPQLVSLDLG FNNLTDLQNM IL GLSTLRH LRLLVLQGNP LSLVPYYRGF TIDSLAHLCV LDDITVSPNE KHQFRGLNIH GDLLAREAQF VVTIGNVRGV LDS SILDPE PGPDGPFISY SYYVTYDFVE DEDMERNVSG LVEATHHDSV LDEIDKHFSG TDEEDQQEDP LDGRHRHRGR QRFH PGSTE EMSKELSEFI AKEMSQMAEG SVESGITEVD WSETSISIHS APLPQSIDSS EELAKLRPKI DIQLCPSPGT VLFNT VHKP WSDVIPCTYE MKHTLKELIR VKAFLLAGTT VSIVEEKILS WPVVPTPVES PLPAKKGKDN NKKKEPAKDK VHKKKK EPP RELRQDPPVL TVLGSGLVYL EPLLAGEAVV STVCNFGVVR TLETDRLTHA RDSKKVKKSL KKDRSKTVPP TMESGYQ PE PLSVEVQIQL HQYRSVEEAF LSLID

UniProtKB: Leucine-rich repeat-containing protein 43

Experimental details

Structure determination

• Method: cryo EM
• Processing: subtomogram averaging
• Aggregation state: cell

Sample preparation

• Buffer: pH: 7
• Vitrification: Cryogen name: ETHANE

Electron microscopy

• Microscope: FEI TITAN KRIOS
• Image recording: Film or detector model: GATAN K2 QUANTUM (4k x 4k) / Detector mode: SUPER-RESOLUTION / Average electron dose: 3.0 e/Ų
• Electron beam: Acceleration voltage: 300 kV / Electron source: FIELD EMISSION GUN
• Electron optics: Illumination mode: SPOT SCAN / Imaging mode: BRIGHT FIELD / Cs: 2.7 mm / Nominal defocus max: 5.0 µm / Nominal defocus min: 1.0 µm
• Experimental equipment: Model: Titan Krios / Image courtesy: FEI Company

Image processing

• Final reconstruction: Resolution.type: BY AUTHOR / Resolution: 7.7 Å / Resolution method: FSC 0.143 CUT-OFF / Number subtomograms used: 19000
• Extraction: Number tomograms: 1889 / Number images used: 105000
• CTF correction: Type: PHASE FLIPPING AND AMPLITUDE CORRECTION
• Final angle assignment: Type: MAXIMUM LIKELIHOOD