登録情報 | データベース: EMDB / ID: EMD-54262 |
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タイトル | Cryo-EM structure of TCRpub/pMHC |
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マップデータ | |
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試料 | - 複合体: Cryo-EM structure of TCRpub/pMHC
- タンパク質・ペプチド: TCRpub alpha chain
- タンパク質・ペプチド: TCRpub beta chain
- タンパク質・ペプチド: MHC class I antigen
- タンパク質・ペプチド: ORF3a protein
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キーワード | complex / IMMUNE SYSTEM |
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機能・相同性 | 機能・相同性情報
host cell lysosome / symbiont-mediated activation of host reticulophagy / Maturation of protein 3a / SARS-CoV-2 modulates autophagy / inorganic cation transmembrane transport / voltage-gated calcium channel complex / host cell endoplasmic reticulum / monoatomic ion channel activity / SARS-CoV-2 targets host intracellular signalling and regulatory pathways / voltage-gated potassium channel complex ...host cell lysosome / symbiont-mediated activation of host reticulophagy / Maturation of protein 3a / SARS-CoV-2 modulates autophagy / inorganic cation transmembrane transport / voltage-gated calcium channel complex / host cell endoplasmic reticulum / monoatomic ion channel activity / SARS-CoV-2 targets host intracellular signalling and regulatory pathways / voltage-gated potassium channel complex / molecular function activator activity / cytoplasmic side of plasma membrane / host cell endosome / Translation of Structural Proteins / Virion Assembly and Release / Induction of Cell-Cell Fusion / Attachment and Entry / host cell endoplasmic reticulum membrane / SARS-CoV-2 activates/modulates innate and adaptive immune responses / host cell plasma membrane / virion membrane / extracellular region / identical protein binding / membrane / plasma membrane類似検索 - 分子機能 Protein 3a, betacoronavirus / 3a-like viroporin, transmembrane domain, alpha/betacoronavirus / 3a-like viroporin, cytosolic domain, alpha/betacoronavirus / Betacoronavirus viroporin / Coronavirus (CoV) 3a-like viroporin trans-membrane (TM) domain profile. / Coronavirus (CoV) 3a-like viroporin cytosolic (CD) domain profile. / MHC class I alpha chain, alpha1 alpha2 domains / Class I Histocompatibility antigen, domains alpha 1 and 2 / : / MHC class I-like antigen recognition-like ...Protein 3a, betacoronavirus / 3a-like viroporin, transmembrane domain, alpha/betacoronavirus / 3a-like viroporin, cytosolic domain, alpha/betacoronavirus / Betacoronavirus viroporin / Coronavirus (CoV) 3a-like viroporin trans-membrane (TM) domain profile. / Coronavirus (CoV) 3a-like viroporin cytosolic (CD) domain profile. / MHC class I alpha chain, alpha1 alpha2 domains / Class I Histocompatibility antigen, domains alpha 1 and 2 / : / MHC class I-like antigen recognition-like / MHC class I-like antigen recognition-like superfamily / MHC classes I/II-like antigen recognition protein / Immunoglobulin/major histocompatibility complex, conserved site / Immunoglobulins and major histocompatibility complex proteins signature. / Immunoglobulin C-Type / Immunoglobulin C1-set / Immunoglobulin C1-set domain / Ig-like domain profile. / Immunoglobulin-like domain / Immunoglobulin-like domain superfamily / Immunoglobulin-like fold類似検索 - ドメイン・相同性 |
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生物種 | Homo sapiens (ヒト) /  Severe acute respiratory syndrome coronavirus 2 (ウイルス) |
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手法 | 単粒子再構成法 / クライオ電子顕微鏡法 / 解像度: 3.26 Å |
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データ登録者 | Akil C / Zhu Y / Hardenbrook N / Zhang P |
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資金援助 | 中国, 英国, 2件 Organization | Grant number | 国 |
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Chinese Academy of Sciences | 2024-I2M-2-001-1 | 中国 | Wellcome Trust | 203141/Z/16/Z | 英国 |
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引用 | ジャーナル: To Be Published タイトル: Cryo-EM structure of TCRpub/pMHC 著者: Akil C / Zhu Y / Hardenbrook N / Zhang P |
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履歴 | 登録 | 2025年7月3日 | - |
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ヘッダ(付随情報) 公開 | 2025年8月13日 | - |
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マップ公開 | 2025年8月13日 | - |
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更新 | 2025年8月13日 | - |
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現状 | 2025年8月13日 | 処理サイト: PDBe / 状態: 公開 |
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